What is Imipramine?

Category: Prescription Drugs

Most popular types: Tofranil Tofranil-PM Tolerade

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Imipramine is a tricyclic antidepressant used for the treatment of depression; treatment of nocturnal enuresis in children. It may also be used as an analgesic for certain chronic and neuropathic pain; panic disorder; and attention-deficit/hyperactivity disorder (ADHD).

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 29 9
Fibromyalgia 16 6
Major depressive disorder 8 17
Pain 8 3
Bladder problems 7 9

Show all 57 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 8
Moderate 11
Mild 12
None 33

Commonly reported side effects and conditions associated with Imipramine

Side effect Patients
Dry mouth 11
Constipation 3
Difficulty with orgasm 3
Blurry vision 2
Drowsiness 2
Dry eyes 2

Show all 32 reported side effects

Dosages

Based on patients currently taking Imipramine

Dosage Patients
25 mg daily 4
10 mg daily 3
0.5 mg daily 1
20 mg daily 1
30 mg daily 1
50 mg daily 1
25 mg three times daily 1
75 mg daily 1

Why patients stopped taking Imipramine

Multiple reasons could be selected

Reason Patients
Did not seem to work 20
Side effects too severe 10
Other 8
Doctor's advice 6
Course of treatment ended 4
Change in health plan coverage 2
Expense 2
Personal research 1
See all 42 patients who've stopped taking Imipramine

Duration

Currently taking Imipramine

Duration Patients
6 months - 1 year 2
1 - 2 years 3
2 - 5 years 2
5 - 10 years 6
10 years or more 1

Stopped taking Imipramine

Duration Patients
Less than 1 month 7
1 - 6 months 10
6 months - 1 year 8
1 - 2 years 4
2 - 5 years 6
5 - 10 years 4
10 years or more 3
Adherence
Adherence Evaluations
Always 61
Usually 3
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 2
A little hard to take 4
Not at all hard to take 56
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 0
$25-49 9
< $25 33
Not specified 22

What people switch to and from

Patients started taking Imipramine after stopping:

Treatment Patients
Nortriptyline (Pamelor) 2
Bupropion (Wellbutrin XL) 1
Citalopram (Celexa) 1
Clomipramine (Anafranil) 1
Desipramine 1

Show all 9 treatments patients report switching from

Patients stopped taking Imipramine and switched to:

Treatment Patients
Amitriptyline (Elavil) 2
Carbamazepine (Tegretol) 2
Citalopram (Celexa) 1
Duloxetine (Cymbalta) 1
Fluoxetine (Prozac) 1

Show all 7 treatments patients report switching to

Last updated:

3 patient evaluations for Imipramine

Mar 25, 2016 (Started Dec 24, 2008)

  • Effectiveness
    Major (for sleep problems)
  • Effectiveness
    Major (for nocturia)
  • Effectiveness
    Major (for bladder problems)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: This remains an effective treatment that allows me to sleep through the night, without needing to pee.
Cost: < $25 monthly

Sep 19, 2015 (Started Dec 24, 2008)

  • Effectiveness
    Major (for sleep problems)
  • Effectiveness
    Major (for nocturia)
  • Effectiveness
    Major (for bladder problems)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Taking 2 pills a night remains very effective.
Cost: < $25 monthly

Jan 24, 2012 (Started Dec 24, 2008)

  • Effectiveness
    Major (for bladder problems)
  • Effectiveness
    Major (for minimize night time bathroom trips)
  • Effectiveness
    Major (for prolong sleeping time periods)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Increasing the dosage to 20mg a night has enabled me to sleep uninterrupted for a significantly longer time period. I now usually stay asleep for between six to ten hours. Plus I don't have to immediately pee upon waking.
Cost: < $25 monthly

Jun 24, 2011 (Started Dec 24, 2008)

  • Effectiveness
    Major (for bladder problems)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I'm using this to cut down on the number of night time bathroom visits I need, which helps me have a longer, more restful sleep. Next month I should be able to split my Vesicare dosage (daytime bladder control), so I will see if the delayed second dose, will extend its benefits to the evening as well.
Cost: < $25 monthly

Jan 13, 2009 (Started Dec 24, 2008)

  • Effectiveness
    Major (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: Just one 10mg pill each evening, has decreased my night time bathroom trips from 4 to 1. Before starting treatment, I had to get up and go every 2 hours. This lengthened to every 4 hours, after about a week and now after a month I'm good for 6 - 8 hours.
Cost: < $25 monthly

  • 0 helpful marks

Oct 23, 2010 (Started Jan 01, 2009)

  • Effectiveness
    Major (for sleep problems)
  • Effectiveness
    Can’t tell (for bipolar mixed episodes)
  • Side effects
    Severe (sudden onset of sleep, morning sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: When this medication is increased by even 50mg, I fall asleep without knowing it within an hour from the drowsiness/grogginess. It had meant I need to make sure I'm not holding anything I can spill or break, or a lit cigarette. This small increase also means the hangover effect is more severe on waking. (Of course, if I were able to stay asleep more than 2-4 hours, the hangover effect would probably not be so strong.) ;)
Cost: < $25 monthly
Side effects: sudden onset of sleep, morning sleepiness

Jul 27, 2010 (Started Jan 01, 2009)

  • Effectiveness
    Moderate (for sleep problems)
  • Effectiveness
    Moderate (for bipolar mixed episodes)
  • Side effects
    Mild (sudden onset of sleep, morning sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Although an "older" antidepressant, the side effect of drowsiness helps with sleep.
Cost: < $25 monthly
Side effects: sudden onset of sleep, morning sleepiness

  • 0 helpful marks

Dec 18, 2009 (Started Feb 14, 2008)

  • Effectiveness
    Can’t tell (for Don't know)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: Another med to take as part of migraine regimen. I didn't want so many meds in my system.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Imipramine