What is Fludrocortisone?

Category: Prescription Drugs

Most popular types: Florinef

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Fludrocortisone is a synthetic corticosteroid. It is used primarily to replace the missing hormone aldosterone in various forms of adrenal insufficiency such as Addison's disease and congenital adrenal hyperplasia. It is the first line of treatment for orthostatic intolerance.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Postural orthostatic tachycardia syndrome 74 39
Addison's disease 32 15
Orthostatic hypotension 31 22
Orthostatic postural hypotension 27 14
Multiple system atrophy 25 12

Show all 49 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
12
Moderate
20
Mild
19
None
49

Commonly reported side effects and conditions associated with Fludrocortisone

Side effect Patients
Weight gain 10
Fluid retention weight gain 6
Headaches 5
Dry mouth 2
Fatigue 2
Migraine headaches 2

Show all 33 reported side effects

Dosages

Based on patients currently taking Fludrocortisone

Dosage Patients
0.1 mg daily 12
0.1 mg twice daily 4
0.2 mg daily 4
0.05 mg daily 3
0.15 mg daily 2
0.025 mg daily 1
0.1 mg every other day 1
0.05 mg twice daily 1
0.1 mg three times daily 1
0.2 mg twice daily 1

See all 12 dosages

Why patients stopped taking Fludrocortisone

Multiple reasons could be selected

Reason Patients
Side effects too severe 22
Did not seem to work 16
Doctor's advice 15
Other 7
Course of treatment ended 5
Personal research 4
See all 54 patients who've stopped taking Fludrocortisone

Duration

Currently taking Fludrocortisone

Duration Patients
1 - 6 months 2
1 - 2 years 5
2 - 5 years 12
5 - 10 years 7
10 years or more 6

Stopped taking Fludrocortisone

Duration Patients
Less than 1 month 14
1 - 6 months 16
6 months - 1 year 8
1 - 2 years 8
2 - 5 years 6
5 - 10 years 4
Adherence
Adherence Evaluations
Always 82
Usually 15
Sometimes 0
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 6
A little hard to take 12
Not at all hard to take 80
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 1
$50-99 0
$25-49 4
< $25 43
Not specified 51

What people switch to and from

Patients started taking Fludrocortisone after stopping:

Treatment Patients
Midodrine (ProAmatine) 6
Prednisone (Deltasone) 2
Pyridostigmine (Mestinon) 1

Patients stopped taking Fludrocortisone and switched to:

Treatment Patients
Midodrine (ProAmatine) 3
Droxidopa (Northera) 1
Irbesartan (Avapro) 1
Prednisone (Deltasone) 1
Propranolol (Inderal) 1
Last updated:

7 patient evaluations for Fludrocortisone

Feb 22, 2010 (Started )

  • Effectiveness
    Moderate (for orthostatic hypotention)
  • Side effects
    Mild (acne breakout)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Side effects: acne breakout

  • 0 helpful marks

Sep 5, 2009 (Started Jul 17, 2009)

  • Effectiveness
    Slight (for orthostatic postural hypotension)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily

  • 0 helpful marks

Apr 15, 2009 (Started Apr 15, 1998)

  • Effectiveness
    Major (for low blood pressure)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 7 patient evaluations for Fludrocortisone