What is Vortioxetine?

Category: Prescription Drugs

Most popular types: Trintellix

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Vortioxetine is a novel and atypical antidepressant used for the treatment of major depressive disorder. The drug acts as a modulator and stimulator of serotonin, a chemical in the body generally associated with well-being and happiness.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 137 124
Generalized anxiety disorder 37 35
Depressed mood 29 17
Bipolar II disorder 8 7
Post-traumatic stress disorder 4 1
Fibromyalgia 3 6

Show all 29 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 26
Moderate 33
Mild 43
None 50

Commonly reported side effects and conditions associated with Vortioxetine

Side effect Patients
Nausea 22
Anxious mood 5
Decreased sex drive (libido) 5
Diarrhea 5
Headaches 5
Constipation 4

Show all 62 reported side effects

Dosages

Based on patients currently taking Vortioxetine

Dosage Patients
20 mg daily 26
10 mg daily 21
5 mg daily 9
15 mg daily 3
2.5 mg daily 1
5 mg twice daily 1
30 mg daily 1

Why patients stopped taking Vortioxetine

Multiple reasons could be selected

Reason Patients
Did not seem to work 39
Side effects too severe 28
Doctor's advice 22
Expense 13
Other 12
Personal research 5
Change in health plan coverage 2
Course of treatment ended 1
See all 77 patients who've stopped taking Vortioxetine

Duration

Currently taking Vortioxetine

Duration Patients
1 - 6 months 8
6 months - 1 year 10
1 - 2 years 20
2 - 5 years 24
10 years or more 1

Stopped taking Vortioxetine

Duration Patients
Less than 1 month 22
1 - 6 months 27
6 months - 1 year 17
1 - 2 years 6
2 - 5 years 5
Adherence
Adherence Evaluations
Always 134
Usually 11
Sometimes 2
Never taken as prescribed 5
Burden
Burden Evaluations
Very hard to take 7
Somewhat hard to take 5
A little hard to take 9
Not at all hard to take 131
Cost per month
Cost per month Evaluations
$200+ 8
$100-199 8
$50-99 19
$25-49 12
< $25 63
Not specified 42

What people switch to and from

Patients started taking Vortioxetine after stopping:

Treatment Patients
Venlafaxine (Effexor XR) 20
Sertraline (Zoloft) 16
Bupropion (Wellbutrin XL) 13
Escitalopram (Lexapro) 13
Citalopram (Celexa) 12

Show all 28 treatments patients report switching from

Patients stopped taking Vortioxetine and switched to:

Treatment Patients
Duloxetine (Cymbalta) 8
Sertraline (Zoloft) 6
Escitalopram (Lexapro) 5
Bupropion (Wellbutrin XL) 4
Fluoxetine (Prozac) 4

Show all 19 treatments patients report switching to

Last updated:

4 patient evaluations for Vortioxetine

Jun 22, 2018 (Started Mar 01, 2015)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: This has proven to be a very effective antidepressant for me. I am very pleased with my mild, infrequent, mostly "life stuff" depressions.
Cost: < $25 monthly

Nov 29, 2015 (Started Mar 01, 2015)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I ran out of Brintellix for several days. The result was obvious increase in depression and increased emotional disarray. It took only two-three days to feel better after starting back up. This anti-depressant is proving as effective as Pristiq and Cymbalta were for me. (Those two lost efficacy with me after 3-4 years. Hopefully this one will be long-standing.
Cost: < $25 monthly

Sep 5, 2015 (Started Mar 01, 2015)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: When I first started Brintellix I was on 10 mg. for a month. Also, I had nausea and vomited three=four times the first couple months. That side effect dissipated.
Cost: < $25 monthly

  • 0 helpful marks

Feb 21, 2018 (Started Jun 15, 2016)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily

  • 0 helpful marks

Feb 5, 2018 (Started Dec 19, 2017)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: It seem to take a long time, about two months, before I notice any positive change. But after about two months I am feeling better. I wanted to increase the dosage to fast, and I started going manic, so I had to bring the dosage back down.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 4 patient evaluations for Vortioxetine