What is Peginterferon beta-1a?

Category: Prescription Drugs

Most popular types: Plegridy

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Peginterferon beta-1a may be used for adults with relapsing forms of MS, in which interferon beta-1a is pegylated to extend its half-life which allows less frequent dosing. It is administered once every 14 days via subcutaneous route.

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 7
Moderate 14
Mild 11
None 7

Commonly reported side effects and conditions associated with Peginterferon beta-1a

Side effect Patients
Injection site redness 3
Extreme flu like malaise 2
Fatigue 2
Fever 2
Headaches 2
Whole body joint ache 2

Show all 24 reported side effects

Dosages

Based on patients currently taking Peginterferon beta-1a

Dosage Patients
125 mcg every other week 5
0.126 mg every other week 4
0.25 mg every other week 2
0.188 mg every other week 1
10 mcg every other week 1
125 mcg weekly 1

Why patients stopped taking Peginterferon beta-1a

Multiple reasons could be selected

Reason Patients
Side effects too severe 12
Did not seem to work 2
Doctor's advice 2
Other 2
Change in health plan coverage 1
See all 19 patients who've stopped taking Peginterferon beta-1a

Duration

Currently taking Peginterferon beta-1a

Duration Patients
6 months - 1 year 1
1 - 2 years 5
2 - 5 years 8

Stopped taking Peginterferon beta-1a

Duration Patients
Less than 1 month 5
1 - 6 months 8
6 months - 1 year 5
1 - 2 years 1
Adherence
Adherence Evaluations
Always 35
Usually 0
Sometimes 3
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 4
A little hard to take 5
Not at all hard to take 30
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 0
$50-99 3
$25-49 1
< $25 21
Not specified 12

What people switch to and from

Patients started taking Peginterferon beta-1a after stopping:

Treatment Patients
Interferon beta-1a IM Injection (Avonex) 14
Dimethyl fumarate (Tecfidera) 10
Interferon beta-1a SubQ injection (Rebif) 10
Glatiramer acetate (Copaxone) 5
Natalizumab (Tysabri) 5

Show all 9 treatments patients report switching from

Patients stopped taking Peginterferon beta-1a and switched to:

Treatment Patients
Teriflunomide (Aubagio) 6
Glatiramer acetate (Copaxone) 4
Dimethyl fumarate (Tecfidera) 2
Interferon beta-1a IM Injection (Avonex) 2
Fingolimod (Gilenya) 1

Show all 7 treatments patients report switching to

Last updated:

1 patient evaluation for Peginterferon beta-1a

Jan 6, 2016 (Started Apr 15, 2015)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 63 mL Every Other Week

Sep 7, 2015 (Started Apr 15, 2015)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 125 mL Every Other Week
Advice & Tips: With not taking this med but once every two weeks I did miss taking one does by two days once. That just means that I had to move the day of my shot out two days from now on. Not a big deal. These needles are like the needles they use for Diabe tics and are so small that they don't hurt at all. Also a Medicare will let you do these at home. So I give them to myself and the spots to give them are 6 instead of just the top of your thighs so you don't get needle fatigue. Love it.

  • 2 helpful marks
Last updated:
Showing 1 of 1 patient evaluation for Peginterferon beta-1a