What is Linaclotide?

Category: Prescription Drugs

Most popular types: Linzess Constella

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Linaclotide is a medication used to control abdominal pain in patients with irritable bowel syndrome.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Constipation 52 20
Irritable bowel syndrome 38 15
Bowel problems 16 5
Chronic constipation 4 3
Bowel irritability 2 1
Abdominal pain 1 0

Show all 11 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 8
Moderate 5
Mild 10
None 13

Commonly reported side effects and conditions associated with Linaclotide

Side effect Patients
Diarrhea 10
Abdominal bloating 5
Bowel irritability 2
Abdominal cramps 1
Chronic diarrhea 1
Diabetes insipidus 1

Show all 17 reported side effects

Dosages

Based on patients currently taking Linaclotide

Dosage Patients
0.145 mg daily 11
0.29 mg daily 4
290 mg daily 4
1 capsule(s) daily 2
0.145 mg weekly 1
0.072 mg daily 1
0.58 mg twice daily 1
10 mg daily 1
290 mcg m,w,f 1
145 capsule(s) daily 1

See all 12 dosages

Why patients stopped taking Linaclotide

Multiple reasons could be selected

Reason Patients
Side effects too severe 9
Did not seem to work 8
Other 3
Doctor's advice 2
Change in health plan coverage 1
Expense 1
See all 22 patients who've stopped taking Linaclotide

Duration

Currently taking Linaclotide

Duration Patients
1 - 6 months 3
6 months - 1 year 1
1 - 2 years 5
2 - 5 years 19
5 - 10 years 1

Stopped taking Linaclotide

Duration Patients
Less than 1 month 7
1 - 6 months 7
6 months - 1 year 3
1 - 2 years 4
2 - 5 years 1
Adherence
Adherence Evaluations
Always 23
Usually 8
Sometimes 4
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 5
A little hard to take 2
Not at all hard to take 29
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 4
$50-99 1
$25-49 3
< $25 10
Not specified 17

What people switch to and from

Patients started taking Linaclotide after stopping:

Treatment Patients
Lubiprostone (Amitiza) 3
Dicyclomine (Bentyl) 1
Docusate (Stool Softener) 1
Lactulose (Generlac) 1
Lorazepam (Ativan) 1

Show all 6 treatments patients report switching from

Patients stopped taking Linaclotide and switched to:

Treatment Patients
Lubiprostone (Amitiza) 5
Last updated:
There are no evaluations for Linaclotide.