What is Nintedanib?

Category: Prescription Drugs

Most popular types: Ofev IPF Phase III Nintedanib (BIBF1120)

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Nintedanib is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF). Nintedanib is a kinase inhibitor that blocks multiple pathways that may be involved in the scarring of lung tissue.

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
19
Moderate
32
Mild
57
None
38

Commonly reported side effects and conditions associated with Nintedanib

Side effect Patients
Diarrhea 76
Nausea 41
Decreased appetite 39
Abdominal pain 34
Indigestion 32
Vomiting 26

Show all 45 reported side effects

Dosages

Based on patients currently taking Nintedanib

Dosage Patients
150 mg twice daily 47
100 mg twice daily 10
300 mg daily 6
300 mg twice daily 3
100 mg daily 1
150 mg daily 1
200 mg twice daily 1

Why patients stopped taking Nintedanib

Multiple reasons could be selected

Reason Patients
Side effects too severe 20
Doctor's advice 10
Other 6
Did not seem to work 2
Expense 1
See all 29 patients who've stopped taking Nintedanib

Duration

Currently taking Nintedanib

Duration Patients
1 - 6 months 2
6 months - 1 year 10
1 - 2 years 22
2 - 5 years 36

Stopped taking Nintedanib

Duration Patients
Less than 1 month 5
1 - 6 months 16
6 months - 1 year 7
1 - 2 years 1
Adherence
Adherence Evaluations
Always 131
Usually 13
Sometimes 0
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 11
A little hard to take 30
Not at all hard to take 100
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 1
$50-99 6
$25-49 16
< $25 48
Not specified 62

What people switch to and from

Patients started taking Nintedanib after stopping:

Treatment Patients
Pirfenidone (Esbriet) 23
Azathioprine (Imuran) 2
Clindamycin (Clindamycin PH 1% Gel) 1
Doxycycline (Doxylin) 1
Fluticasone (Flovent HFA) 1

Show all 9 treatments patients report switching from

Patients stopped taking Nintedanib and switched to:

Treatment Patients
Pirfenidone (Esbriet) 12
Azathioprine (Imuran) 1
Mycophenolate mofetil (CellCept) 1
Oxygen therapy (Homozon Oxygen Therapy) 1
Last updated:
There are no evaluations for Nintedanib.