What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,276 1,287
Depressed mood 1,610 795
Persistent depressive disorder (dysthymia) 397 324
Mild depression 153 65
Anxious mood 122 65

Show all 195 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
272
Moderate
379
Mild
612
None
1,126

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 106
Anxious mood 71
Weight gain 57
Insomnia 50
Headaches 48
Constipation 43

Show all 444 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 182
150 mg daily 144
100 mg daily 68
300 mg/24 hours daily 65
450 mg daily 52
75 mg daily 49
150 mg twice daily 34
200 mg daily 32
100 mg twice daily 30
150 mg/24 hours daily 26

See all 71 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 656
Side effects too severe 554
Doctor's advice 426
Other 276
Course of treatment ended 91
Expense 81
Personal research 71
Change in health plan coverage 43
See all 1598 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 51
6 months - 1 year 98
1 - 2 years 110
2 - 5 years 220
5 - 10 years 191
10 years or more 169

Stopped taking Bupropion

Duration Patients
Less than 1 month 354
1 - 6 months 356
6 months - 1 year 232
1 - 2 years 230
2 - 5 years 280
5 - 10 years 124
10 years or more 60
Adherence
Adherence Evaluations
Always 1868
Usually 356
Sometimes 54
Never taken as prescribed 111
Burden
Burden Evaluations
Very hard to take 83
Somewhat hard to take 147
A little hard to take 341
Not at all hard to take 1818
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 26
$50-99 86
$25-49 174
< $25 1153
Not specified 937

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 89
Venlafaxine (Effexor XR) 72
Citalopram (Celexa) 53
Duloxetine (Cymbalta) 48

Show all 57 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 50
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 32
Fluoxetine (Prozac) 31

Show all 47 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 15, 2017 (Started Jun 01, 2006)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (insomnia, hot flashes, feeling tense or on edge, feeling feverish, facial flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: If you are taking the generic extended release make sure it is not dose dumping - releasing too much medicine at once causing side effects. My MS doctor, PCP, and I thought I was in menopause with all the hot flashes and fevers of 99.6! Even kept going in to see if I had a UTI bc of the fevers! What a waste of my time and money!!!
Cost: < $25 monthly

  • 0 helpful marks

Dec 1, 2017 (Started Jul 01, 2007)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion