What is Sulfasalazine?

Category: Prescription Drugs

Most popular types: Salazopyrin Sulfazine Azulfidine Show all

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Sulfasalazine is a 5-aminosalicylic acid derivative used primarily for ulcerative colitis and rheumatoid arthritis. It has many other uses including ankylosing spondylitis, collagenous colitis, Crohn's disease, psoriasis, psoriatic arthritis, juvenile chronic arthritis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 378 156
Crohn's disease 76 24
Psoriatic arthritis 55 16
Ulcerative colitis 53 24
Ankylosing spondylitis 31 13

Show all 33 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 57
Moderate 46
Mild 53
None 106

Commonly reported side effects and conditions associated with Sulfasalazine

Side effect Patients
Nausea 28
Headaches 17
Rashes (redness, swelling) 8
Diarrhea 7
Stomach pain 7
Fatigue 5

Show all 100 reported side effects

Dosages

Based on patients currently taking Sulfasalazine

Dosage Patients
500 mg twice daily 16
1,500 mg twice daily 13
1,000 mg twice daily 9
2,000 mg daily 6
3,000 mg daily 5
500 mg daily 3
1,000 mg daily 3
500 mg four times daily 2
1,000 mg three times daily 2
1.5 g daily 1

See all 15 dosages

Why patients stopped taking Sulfasalazine

Multiple reasons could be selected

Reason Patients
Did not seem to work 144
Side effects too severe 130
Doctor's advice 87
Other 38
Course of treatment ended 18
Personal research 10
Expense 5
Change in health plan coverage 4
See all 315 patients who've stopped taking Sulfasalazine

Duration

Currently taking Sulfasalazine

Duration Patients
Less than 1 month 1
1 - 6 months 11
6 months - 1 year 8
1 - 2 years 6
2 - 5 years 13
5 - 10 years 19
10 years or more 11

Stopped taking Sulfasalazine

Duration Patients
Less than 1 month 72
1 - 6 months 77
6 months - 1 year 46
1 - 2 years 39
2 - 5 years 52
5 - 10 years 15
10 years or more 14
Adherence
Adherence Evaluations
Always 205
Usually 34
Sometimes 8
Never taken as prescribed 15
Burden
Burden Evaluations
Very hard to take 22
Somewhat hard to take 23
A little hard to take 52
Not at all hard to take 165
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 2
$50-99 2
$25-49 15
< $25 101
Not specified 141

What people switch to and from

Patients started taking Sulfasalazine after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 19
Hydroxychloroquine (Plaquenil) 9
Mesalamine (Pentasa) 9
Adalimumab (Humira) 7
Leflunomide (Arava) 5

Show all 18 treatments patients report switching from

Patients stopped taking Sulfasalazine and switched to:

Treatment Patients
Mesalamine (Pentasa) 10
Methotrexate (Apo-Methotrexate) 10
Infliximab (Remicade) 7
Adalimumab (Humira) 6
Leflunomide (Arava) 6

Show all 19 treatments patients report switching to

Last updated:

18 patient evaluations for Sulfasalazine

Apr 5, 2017 (Started Feb 09, 2009)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 3000 mg Daily
Cost: < $25 monthly

Jun 7, 2013 (Started Feb 09, 2009)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Sulfasalazine seems to build up in my body, so it does not help if I only took the med before bedtime. Even the side effect is rather mild, it is present 24/7 and I can't have it.

Mar 18, 2013 (Started Feb 09, 2009)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily

Dec 3, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Det var en ubetinget succes at gå ned til 500mg. Det kunne kun lade sig gøre fordi jeg satte mtx dosis op til 9 pr uge. En dag tager jeg mod til mig og dropper Sulfasalazine fuldstændigt som forsøg.

Oct 5, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily
Advice & Tips: I 7 uger har jeg kun taget 2 stk (1000mg) og det har reduceret kvalmen ganske betydeligt. På mandag sætter jeg det ned til 1 stk (500mg)

Jul 6, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: Take quarter dose in the morning, quarter in the evening and half before bedtime

  • 0 helpful marks

Jan 15, 2016 (Started Jan 15, 2015)

  • Effectiveness
    Can't tell (for ankylosing spondylitis)
  • Side effects
    Moderate (diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Twice daily

  • 0 helpful marks

Jul 1, 2014 (Started Feb 15, 2012)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: RA went into remission.

Jul 1, 2013 (Started Feb 15, 2012)

  • Effectiveness
    Major (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 18 patient evaluations for Sulfasalazine