What is Sulfasalazine?

Category: Prescription Drugs

Most popular types: Salazopyrin Sulfazine Azulfidine Show all

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Sulfasalazine is a 5-aminosalicylic acid derivative used primarily for ulcerative colitis and rheumatoid arthritis. It has many other uses including ankylosing spondylitis, collagenous colitis, Crohn's disease, psoriasis, psoriatic arthritis, juvenile chronic arthritis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 359 151
Crohn's disease 75 22
Psoriatic arthritis 54 17
Ulcerative colitis 50 22
Ankylosing spondylitis 30 13

Show all 33 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 55
Moderate 45
Mild 53
None 99

Commonly reported side effects and conditions associated with Sulfasalazine

Side effect Patients
Nausea 27
Headaches 16
Rashes (redness, swelling) 8
Nausea and vomiting 7
Stomach pain 7
Diarrhea 6

Show all 118 reported side effects

Dosages

Based on patients currently taking Sulfasalazine

Dosage Patients
1,000 mg twice daily 11
2,000 mg daily 10
1,500 mg twice daily 8
500 mg twice daily 7
1,000 mg daily 5
3,000 mg daily 5
500 mg daily 4
2,500 mg daily 2
1,000 mg three times daily 2
1.5 g daily 1

See all 12 dosages

Why patients stopped taking Sulfasalazine

Multiple reasons could be selected

Reason Patients
Did not seem to work 141
Side effects too severe 127
Doctor's advice 86
Other 36
Course of treatment ended 18
Personal research 10
Expense 5
Change in health plan coverage 4
See all 308 patients who've stopped taking Sulfasalazine

Duration

Currently taking Sulfasalazine

Duration Patients
Less than 1 month 2
1 - 6 months 3
6 months - 1 year 3
1 - 2 years 9
2 - 5 years 15
5 - 10 years 17
10 years or more 10

Stopped taking Sulfasalazine

Duration Patients
Less than 1 month 69
1 - 6 months 77
6 months - 1 year 46
1 - 2 years 39
2 - 5 years 50
5 - 10 years 13
10 years or more 14
Adherence
Adherence Evaluations
Always 197
Usually 34
Sometimes 7
Never taken as prescribed 14
Burden
Burden Evaluations
Very hard to take 22
Somewhat hard to take 20
A little hard to take 49
Not at all hard to take 161
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 2
$50-99 2
$25-49 14
< $25 102
Not specified 131

What people switch to and from

Patients started taking Sulfasalazine after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 17
Hydroxychloroquine (Plaquenil) 9
Mesalamine (Pentasa) 8
Adalimumab (Humira) 6
Prednisone (Deltasone) 5

Show all 17 treatments patients report switching from

Patients stopped taking Sulfasalazine and switched to:

Treatment Patients
Mesalamine (Pentasa) 9
Methotrexate (Apo-Methotrexate) 9
Infliximab (Remicade) 7
Adalimumab (Humira) 6
Hydroxychloroquine (Plaquenil) 5

Show all 16 treatments patients report switching to

Last updated:

18 patient evaluations for Sulfasalazine

Apr 5, 2017 (Started Feb 09, 2009)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 3000 mg Daily
Cost: < $25 monthly

Jun 7, 2013 (Started Feb 09, 2009)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Sulfasalazine seems to build up in my body, so it does not help if I only took the med before bedtime. Even the side effect is rather mild, it is present 24/7 and I can't have it.

Mar 18, 2013 (Started Feb 09, 2009)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily

Dec 3, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Det var en ubetinget succes at gå ned til 500mg. Det kunne kun lade sig gøre fordi jeg satte mtx dosis op til 9 pr uge. En dag tager jeg mod til mig og dropper Sulfasalazine fuldstændigt som forsøg.

Oct 5, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily
Advice & Tips: I 7 uger har jeg kun taget 2 stk (1000mg) og det har reduceret kvalmen ganske betydeligt. På mandag sætter jeg det ned til 1 stk (500mg)

Jul 6, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (feeling sick)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: Take quarter dose in the morning, quarter in the evening and half before bedtime

  • 0 helpful marks

Jan 15, 2016 (Started Jan 15, 2015)

  • Effectiveness
    Can't tell (for ankylosing spondylitis)
  • Side effects
    Moderate (diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Twice daily

  • 0 helpful marks

Jul 1, 2014 (Started Feb 15, 2012)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: RA went into remission.

Jul 1, 2013 (Started Feb 15, 2012)

  • Effectiveness
    Major (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 18 patient evaluations for Sulfasalazine