What is Sulfasalazine?

Category: Prescription Drugs

Most popular types: Salazopyrin Sulfazine Azulfidine Show all

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Sulfasalazine is a 5-aminosalicylic acid derivative used primarily for ulcerative colitis and rheumatoid arthritis. It has many other uses including ankylosing spondylitis, collagenous colitis, Crohn's disease, psoriasis, psoriatic arthritis, juvenile chronic arthritis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 337 140
Crohn's disease 69 20
Psoriatic arthritis 52 17
Ulcerative colitis 50 21
Ankylosing spondylitis 28 13

Show all 33 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 52
Moderate 44
Mild 52
None 89

Commonly reported side effects and conditions associated with Sulfasalazine

Side effect Patients
Nausea 25
Headaches 14
Nausea and vomiting 7
Rash 7
Stomach pain 6
Diarrhea 5

Show all 118 reported side effects

Dosages

Based on patients currently taking Sulfasalazine

Dosage Patients
1,000 mg twice daily 16
2,000 mg daily 9
500 mg twice daily 5
1,500 mg twice daily 5
3,000 mg daily 4
1,000 mg daily 3
1,000 mg three times daily 2
1.5 g daily 1
500 mg daily 1
2,000 g daily 1

See all 11 dosages

Why patients stopped taking Sulfasalazine

Multiple reasons could be selected

Reason Patients
Did not seem to work 130
Side effects too severe 121
Doctor's advice 83
Other 35
Course of treatment ended 18
Personal research 9
Expense 5
Change in health plan coverage 3
See all 287 patients who've stopped taking Sulfasalazine

Duration

Currently taking Sulfasalazine

Duration Patients
1 - 6 months 1
6 months - 1 year 6
1 - 2 years 6
2 - 5 years 15
5 - 10 years 14
10 years or more 8

Stopped taking Sulfasalazine

Duration Patients
Less than 1 month 61
1 - 6 months 78
6 months - 1 year 40
1 - 2 years 36
2 - 5 years 47
5 - 10 years 12
10 years or more 13
Adherence
Adherence Evaluations
Always 184
Usually 33
Sometimes 7
Never taken as prescribed 13
Burden
Burden Evaluations
Very hard to take 21
Somewhat hard to take 18
A little hard to take 49
Not at all hard to take 149
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 1
$50-99 2
$25-49 14
< $25 96
Not specified 123

What people switch to and from

Patients started taking Sulfasalazine after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 17
Hydroxychloroquine (Plaquenil) 7
Mesalamine (Pentasa) 6
Adalimumab (Humira) 5
Prednisone (Deltasone) 5

Show all 18 treatments patients report switching from

Patients stopped taking Sulfasalazine and switched to:

Treatment Patients
Mesalamine (Pentasa) 7
Methotrexate (Apo-Methotrexate) 6
Adalimumab (Humira) 5
Infliximab (Remicade) 5
Etanercept (Enbrel SureClick) 3

Show all 16 treatments patients report switching to

Last updated:

18 patient evaluations for Sulfasalazine

Apr 5, 2017 (Started Feb 09, 2009)

  • Effectiveness
    Can’t tell (for rheumatoid arthritis)
  • Side effects
    Mild (Feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 3000 mg Daily
Cost: < $25 monthly

Jun 7, 2013 (Started Feb 09, 2009)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Mild (Feeling sick)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Sulfasalazine seems to build up in my body, so it does not help if I only took the med before bedtime. Even the side effect is rather mild, it is present 24/7 and I can't have it.

Mar 18, 2013 (Started Feb 09, 2009)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    Mild (Feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily

Dec 3, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: Det var en ubetinget succes at gå ned til 500mg. Det kunne kun lade sig gøre fordi jeg satte mtx dosis op til 9 pr uge. En dag tager jeg mod til mig og dropper Sulfasalazine fuldstændigt som forsøg.

Oct 5, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (Feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily
Advice & Tips: I 7 uger har jeg kun taget 2 stk (1000mg) og det har reduceret kvalmen ganske betydeligt. På mandag sætter jeg det ned til 1 stk (500mg)

Jul 6, 2012 (Started Feb 09, 2009)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    Mild (Feeling sick)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: Take quarter dose in the morning, quarter in the evening and half before bedtime

  • 0 helpful marks

Jan 15, 2016 (Started Jan 15, 2015)

  • Effectiveness
    Can’t tell (for ankylosing spondylitis)
  • Side effects
    Moderate (Diarrhea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1500 mg Twice daily

  • 0 helpful marks

Jul 1, 2014 (Started Feb 15, 2012)

  • Effectiveness
    Moderate (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: RA went into remission.

Jul 1, 2013 (Started Feb 15, 2012)

  • Effectiveness
    Major (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 18 patient evaluations for Sulfasalazine