What is Acetaminophen (paracetamol)-diphenhydramine-phenylephrine?

Category: Over the Counter Drugs

Most popular types: Benadryl Allergy Sinus Headache Robitussin Peak Cold Nighttime Multi-Symptom Cold


This combination product contains acetaminophen (a pain reliever and fever reducer) along with phenylephrine (a nasal decongestant) and diphenhydramine (an antihistamine). These three agents may be used to treat the pain and discomfort of allergies and sinus congestion as well as headache.

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 0
Moderate 0
Mild 0
None 1

Commonly reported side effects and conditions associated with Acetaminophen (paracetamol)-diphenhydramine-phenylephrine

Side effect Patients


Based on patients currently taking Acetaminophen (paracetamol)-diphenhydramine-phenylephrine

Dosage Patients
2 x 325-25-5 mg daily 1

Why patients stopped taking Acetaminophen (paracetamol)-diphenhydramine-phenylephrine

Multiple reasons could be selected

Reason Patients
Course of treatment ended 1
Other 1
See all 2 patients who've stopped taking Acetaminophen (paracetamol)-diphenhydramine-phenylephrine


Currently taking Acetaminophen (paracetamol)-diphenhydramine-phenylephrine

Duration Patients
6 months - 1 year 1

Stopped taking Acetaminophen (paracetamol)-diphenhydramine-phenylephrine

Duration Patients
Less than 1 month 1
6 months - 1 year 1
Adherence Evaluations
Always 1
Usually 0
Sometimes 0
Never taken as prescribed 0
Burden Evaluations
Very hard to take 0
Somewhat hard to take 0
A little hard to take 0
Not at all hard to take 1
Last updated:

1 patient evaluation for Acetaminophen (paracetamol)-diphenhydramine-phenylephrine

Feb 4, 2010 (Started Jul 01, 2009)

  • Effectiveness
    Major (for Pre-Medication For Rebif Shot (Tues. Thurs. Sat))
  • Side effects
  • Adherence
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks
Last updated:
Showing 1 of 1 patient evaluation for Acetaminophen (paracetamol)-diphenhydramine-phenylephrine