What is Linaclotide?

Category: Prescription Drugs

Most popular types: Linzess Constella

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Linaclotide is a medication used to control abdominal pain in patients with irritable bowel syndrome.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Constipation 48 25
Irritable bowel syndrome 34 20
Bowel problems 16 10
Chronic constipation 4 3
Bowel irritability 2 1
Abdominal pain 1 0

Show all 9 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
8
Moderate
5
Mild
15
None
11

Commonly reported side effects and conditions associated with Linaclotide

Side effect Patients
Diarrhea 11
Abdominal bloating 5
Bowel irritability 2
Abdominal cramps 1
Constipation 1
Diabetes insipidus 1

Show all 14 reported side effects

Dosages

Based on patients currently taking Linaclotide

Dosage Patients
0.145 mg daily 12
0.29 mg daily 6
290 mg daily 5
0.072 mg daily 3
1 capsule(s) daily 2
290 mcg m,w,f 2
145 mcg daily 2
0.145 mg weekly 1
145 capsule(s) daily 1
290 mcg daily 1

See all 11 dosages

Why patients stopped taking Linaclotide

Multiple reasons could be selected

Reason Patients
Side effects too severe 8
Did not seem to work 6
Change in health plan coverage 1
Doctor's advice 1
Expense 1
Other 1
See all 17 patients who've stopped taking Linaclotide

Duration

Currently taking Linaclotide

Duration Patients
1 - 6 months 3
6 months - 1 year 8
1 - 2 years 7
2 - 5 years 18

Stopped taking Linaclotide

Duration Patients
Less than 1 month 7
1 - 6 months 6
6 months - 1 year 1
1 - 2 years 3
Adherence
Adherence Evaluations
Always 24
Usually 10
Sometimes 3
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 5
A little hard to take 4
Not at all hard to take 30
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 5
$50-99 1
$25-49 8
< $25 9
Not specified 15

What people switch to and from

Patients started taking Linaclotide after stopping:

Treatment Patients
Lubiprostone (Amitiza) 3
Dicyclomine (Bentyl) 1
Lactulose (Generlac) 1
Lorazepam (Ativan) 1
Polyethylene Glycol 3350 (MiraLax) 1

Patients stopped taking Linaclotide and switched to:

Treatment Patients
Lubiprostone (Amitiza) 5
Last updated:
There are no evaluations for Linaclotide.