What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,110 3,075
Depressed mood 2,000 1,150
Major depressive disorder 1,775 1,088
Generalized anxiety disorder 759 536
Myalgic encephalomyelitis/chronic fatigue syndrome 693 380
Pain 523 301

Show all 354 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 899
Moderate 975
Mild 1,111
None 1,657

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 300
Nausea 289
Dizziness 159
Dry mouth 159
Sex drive (libido) decreased 157
Sweating increased 100

Show all 727 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 478
30 mg daily 182
120 mg daily 131
90 mg daily 93
60 mg twice daily 86
20 mg daily 80
30 mg twice daily 51
40 mg daily 32
120 mg twice daily 21
20 mg twice daily 16

See all 53 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1700
Did not seem to work 1490
Doctor's advice 561
Expense 439
Other 418
Personal research 167
Change in health plan coverage 156
Course of treatment ended 66
See all 3364 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 5
1 - 6 months 94
6 months - 1 year 107
1 - 2 years 206
2 - 5 years 396
5 - 10 years 345
10 years or more 144

Stopped taking Duloxetine

Duration Patients
Less than 1 month 727
1 - 6 months 951
6 months - 1 year 552
1 - 2 years 482
2 - 5 years 497
5 - 10 years 139
10 years or more 32
Adherence
Adherence Evaluations
Always 3893
Usually 408
Sometimes 68
Never taken as prescribed 273
Burden
Burden Evaluations
Very hard to take 293
Somewhat hard to take 359
A little hard to take 543
Not at all hard to take 3447
Cost per month
Cost per month Evaluations
$200+ 124
$100-199 187
$50-99 428
$25-49 672
< $25 1489
Not specified 1742

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 147
Fluoxetine (Prozac) 111
Venlafaxine (Effexor XR) 107
Sertraline (Zoloft) 89
Citalopram (Celexa) 85

Show all 70 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 72
Venlafaxine (Effexor XR) 60
Gabapentin (Neurontin) 51
Sertraline (Zoloft) 35
Bupropion (Wellbutrin XL) 32

Show all 70 treatments patients report switching to

Last updated:

318 patient evaluations for Duloxetine

May 18, 2010 (Started May 18, 2007)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: No biggie. Easy. worth it.
Cost: < $25 monthly
Side effects: Weight gain

  • 1 helpful mark

Jul 22, 2010 (Started Jun 15, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Dry throat, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta was a like a miracle drug for me when I first started taking it. I can tell if I have forgotten to take it or haven't refilled my script. I highly recommend it for treatment of Fibromyalgia. I still experience some depression, but that is probably normal for someone living in chronic pain.
Cost: $100-199 monthly
Side effects: Dry mouth, Dry throat

  • 1 helpful mark

Aug 1, 2010 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Pain)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I believe this med was great for me..in order to manage other symptoms as well i was taken off this med and put on another to see if other symptoms were helped.
Cost: < $25 monthly

Aug 20, 2008 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Take it as prescribed and it helps the pain.If you stop taking it for a couple of days you will definitly feel the difference!!So keep taking it.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 318 patient evaluations for Duloxetine