What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,300 3,169
Depressed mood 2,057 1,205
Major depressive disorder 1,873 1,132
Generalized anxiety disorder 789 552
Myalgic encephalomyelitis/chronic fatigue syndrome 696 387
Pain 534 313

Show all 326 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
922
Moderate
1,002
Mild
1,133
None
1,727

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 315
Nausea 286
Dry mouth 166
Dizziness 158
Decreased sex drive (libido) 153
Sweating increased 100

Show all 747 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 444
30 mg daily 172
120 mg daily 129
90 mg daily 76
60 mg twice daily 76
20 mg daily 71
30 mg twice daily 31
40 mg daily 22
120 mg twice daily 16
20 mg twice daily 13

See all 45 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1740
Did not seem to work 1530
Doctor's advice 579
Expense 444
Other 427
Personal research 169
Change in health plan coverage 159
Course of treatment ended 69
See all 3451 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
1 - 6 months 53
6 months - 1 year 101
1 - 2 years 165
2 - 5 years 331
5 - 10 years 337
10 years or more 147

Stopped taking Duloxetine

Duration Patients
Less than 1 month 809
1 - 6 months 931
6 months - 1 year 542
1 - 2 years 489
2 - 5 years 511
5 - 10 years 153
10 years or more 33
Adherence
Adherence Evaluations
Always 4005
Usually 423
Sometimes 73
Never taken as prescribed 283
Burden
Burden Evaluations
Very hard to take 299
Somewhat hard to take 365
A little hard to take 558
Not at all hard to take 3562
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 191
$50-99 430
$25-49 686
< $25 1547
Not specified 1804

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 124
Venlafaxine (Effexor XR) 121
Sertraline (Zoloft) 108
Citalopram (Celexa) 95

Show all 75 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 78
Venlafaxine (Effexor XR) 68
Gabapentin (Neurontin) 58
Escitalopram (Lexapro) 36
Sertraline (Zoloft) 36

Show all 77 treatments patients report switching to

Last updated:

319 patient evaluations for Duloxetine

May 18, 2010 (Started May 18, 2007)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: No biggie. Easy. worth it.
Cost: < $25 monthly
Side effects: weight gain

  • 1 helpful mark

Jul 22, 2010 (Started Jun 15, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (dry throat, dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta was a like a miracle drug for me when I first started taking it. I can tell if I have forgotten to take it or haven't refilled my script. I highly recommend it for treatment of Fibromyalgia. I still experience some depression, but that is probably normal for someone living in chronic pain.
Cost: $100-199 monthly
Side effects: dry mouth, dry throat

  • 1 helpful mark

Aug 1, 2010 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for pain)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I believe this med was great for me..in order to manage other symptoms as well i was taken off this med and put on another to see if other symptoms were helped.
Cost: < $25 monthly

Aug 20, 2008 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Take it as prescribed and it helps the pain.If you stop taking it for a couple of days you will definitly feel the difference!!So keep taking it.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 319 patient evaluations for Duloxetine