What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,887 2,900
Depressed mood 1,957 1,107
Major Depressive Disorder 1,661 1,011
Generalized Anxiety Disorder 718 506
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 686 369
Pain 518 291

Show all 345 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 863
Moderate 920
Mild 1,069
None 1,555

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 276
Nausea 273
Dizziness 157
Sex drive (libido) decreased 154
Dry mouth 152
Sweating increased 100

Show all 713 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 507
30 mg daily 221
120 mg daily 127
60 mg twice daily 93
90 mg daily 91
20 mg daily 73
30 mg twice daily 49
40 mg daily 34
120 mg twice daily 24
20 mg twice daily 9

See all 59 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1655
Did not seem to work 1441
Doctor's advice 538
Expense 428
Other 407
Personal research 159
Change in health plan coverage 151
Course of treatment ended 63
See all 3256 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 10
1 - 6 months 101
6 months - 1 year 184
1 - 2 years 240
2 - 5 years 354
5 - 10 years 332
10 years or more 134

Stopped taking Duloxetine

Duration Patients
Less than 1 month 708
1 - 6 months 931
6 months - 1 year 533
1 - 2 years 464
2 - 5 years 478
5 - 10 years 128
10 years or more 30
Adherence
Adherence Evaluations
Always 3708
Usually 385
Sometimes 63
Never taken as prescribed 251
Burden
Burden Evaluations
Very hard to take 270
Somewhat hard to take 342
A little hard to take 517
Not at all hard to take 3278
Cost per month
Cost per month Evaluations
$200+ 122
$100-199 186
$50-99 416
$25-49 652
< $25 1387
Not specified 1644

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 126
Fluoxetine (Prozac) 97
Venlafaxine (Effexor XR) 89
Sertraline (Zoloft) 81
Escitalopram (Lexapro) 73

Show all 67 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 60
Venlafaxine (Effexor XR) 55
Gabapentin (Neurontin) 39
Bupropion (Wellbutrin XL) 30
Sertraline (Zoloft) 30

Show all 66 treatments patients report switching to

Last updated:

315 patient evaluations for Duloxetine

3,571 members have decided to share their profiles only with other members of PatientsLikeMe.

eman
14444 thumb
eman
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: mild
Upper limb: none
Walking: mild
I am: n
I have:
MS

See eman's full Duloxetine history

May 18, 2010 (Started May 18, 2007)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: No biggie. Easy. worth it.
Cost: < $25 monthly
Side effects: Weight gain

  • 1 helpful mark
Txredhead
25564 thumb
Txredhead
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: All
Sleep: All
Stiffness: All
function: None
external_stress: All
Stickman: all
Description:F55y
FM:26y Dx
CFS:29y Dx
I am: vb
I have:
Fibromyalgia

See Txredhead's full Duloxetine history

Jul 22, 2010 (Started Jun 15, 2009)

  • Effectiveness
    Major (for Fibromyalgia)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Dry throat, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta was a like a miracle drug for me when I first started taking it. I can tell if I have forgotten to take it or haven't refilled my script. I highly recommend it for treatment of Fibromyalgia. I still experience some depression, but that is probably normal for someone living in chronic pain.
Cost: $100-199 monthly
Side effects: Dry mouth, Dry throat

  • 1 helpful mark
Babystars
1954 thumb
Babystars
Sex: F
Data Quality: 1 star
Relapse: Moderate
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: none
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See Babystars's full Duloxetine history

Aug 1, 2010 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Pain)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I believe this med was great for me..in order to manage other symptoms as well i was taken off this med and put on another to see if other symptoms were helped.
Cost: < $25 monthly

Aug 20, 2008 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Take it as prescribed and it helps the pain.If you stop taking it for a couple of days you will definitly feel the difference!!So keep taking it.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 315 patient evaluations for Duloxetine