What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,199 2,397
Depressed mood 1,850 1,024
Major Depressive Disorder 1,345 783
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 679 354
Generalized Anxiety Disorder 652 462
Pain 500 280

Show all 321 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 759
Moderate 808
Mild 911
None 1,227

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Nausea 234
Weight gain 220
Sex drive (libido) decreased 151
Dizziness 138
Dry mouth 124
Sweating increased 96

Show all 655 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 250
30 mg daily 119
120 mg daily 64
90 mg daily 49
60 mg twice daily 33
20 mg daily 29
30 mg twice daily 18
40 mg daily 11
20 mg twice daily 5
120 mg twice daily 5

See all 36 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1555
Did not seem to work 1311
Doctor's advice 504
Expense 409
Other 380
Personal research 146
Change in health plan coverage 141
Course of treatment ended 61
See all 3016 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 8
1 - 6 months 46
6 months - 1 year 39
1 - 2 years 90
2 - 5 years 179
5 - 10 years 196
10 years or more 63

Stopped taking Duloxetine

Duration Patients
Less than 1 month 635
1 - 6 months 901
6 months - 1 year 484
1 - 2 years 430
2 - 5 years 437
5 - 10 years 118
10 years or more 26
Adherence
Adherence Evaluations
Always 3134
Usually 330
Sometimes 55
Never taken as prescribed 186
Burden
Burden Evaluations
Very hard to take 228
Somewhat hard to take 292
A little hard to take 453
Not at all hard to take 2732
Cost per month
Cost per month Evaluations
$200+ 114
$100-199 169
$50-99 386
$25-49 580
< $25 1067
Not specified 1389

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 61
Venlafaxine (Effexor XR) 56
Fluoxetine (Prozac) 52
Escitalopram (Lexapro) 47
Sertraline (Zoloft) 46

Show all 53 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 42
Pregabalin (Lyrica) 30
Bupropion (Wellbutrin XL) 23
Sertraline (Zoloft) 22
Gabapentin (Neurontin) 21

Show all 51 treatments patients report switching to

Last updated:

317 patient evaluations for Duloxetine

2,940 members have decided to share their profiles only with other members of PatientsLikeMe.

eman
14444 thumb
eman
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: mild
Upper limb: none
Walking: mild
I am: n
I have:
MS

See eman's full Duloxetine history

May 18, 2010 (Started May 18, 2007)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: No biggie. Easy. worth it.
Cost: < $25 monthly
Side effects: Weight gain

  • 1 helpful mark
Txredhead
25564 thumb
Txredhead
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: All
Sleep: All
Stiffness: All
function: None
external_stress: All
Stickman: all
Description:F55y
FM:25y Dx
CFS:28y Dx
I am: vb
I have:
Fibromyalgia

See Txredhead's full Duloxetine history

Jul 22, 2010 (Started Jun 15, 2009)

  • Effectiveness
    Major (for Fibromyalgia)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Dry throat, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta was a like a miracle drug for me when I first started taking it. I can tell if I have forgotten to take it or haven't refilled my script. I highly recommend it for treatment of Fibromyalgia. I still experience some depression, but that is probably normal for someone living in chronic pain.
Cost: $100-199 monthly
Side effects: Dry mouth, Dry throat

  • 1 helpful mark
Babystars
1954 thumb
Babystars
Sex: F
Data Quality: 1 star
Relapse: Moderate
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: none
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See Babystars's full Duloxetine history

Aug 1, 2010 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Pain)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I believe this med was great for me..in order to manage other symptoms as well i was taken off this med and put on another to see if other symptoms were helped.
Cost: < $25 monthly

Aug 20, 2008 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Take it as prescribed and it helps the pain.If you stop taking it for a couple of days you will definitly feel the difference!!So keep taking it.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 317 patient evaluations for Duloxetine