What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
fibromyalgia 6,017 3,004
Depressed mood 1,980 1,134
major depressive disorder 1,732 1,057
generalized anxiety disorder 748 528
myalgic encephalomyelitis/chronic fatigue syndrome 691 375
Pain 520 296

Show all 352 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 884
Moderate 954
Mild 1,093
None 1,616

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 291
Nausea 281
Dizziness 158
Dry mouth 156
Sex drive (libido) decreased 155
Sweating increased 99

Show all 726 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 542
30 mg daily 230
120 mg daily 133
90 mg daily 111
60 mg twice daily 101
20 mg daily 83
30 mg twice daily 58
40 mg daily 40
120 mg twice daily 24
20 mg twice daily 16

See all 57 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1678
Did not seem to work 1463
Doctor's advice 550
Expense 433
Other 412
Personal research 165
Change in health plan coverage 153
Course of treatment ended 66
See all 3310 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 3
1 - 6 months 98
6 months - 1 year 213
1 - 2 years 266
2 - 5 years 392
5 - 10 years 362
10 years or more 145

Stopped taking Duloxetine

Duration Patients
Less than 1 month 715
1 - 6 months 944
6 months - 1 year 540
1 - 2 years 472
2 - 5 years 489
5 - 10 years 134
10 years or more 32
Adherence
Adherence Evaluations
Always 3817
Usually 400
Sometimes 68
Never taken as prescribed 262
Burden
Burden Evaluations
Very hard to take 283
Somewhat hard to take 352
A little hard to take 535
Not at all hard to take 3377
Cost per month
Cost per month Evaluations
$200+ 122
$100-199 188
$50-99 422
$25-49 659
< $25 1452
Not specified 1704

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 132
Fluoxetine (Prozac) 106
Venlafaxine (Effexor XR) 99
Sertraline (Zoloft) 87
Citalopram (Celexa) 79

Show all 70 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 66
Venlafaxine (Effexor XR) 56
Gabapentin (Neurontin) 44
Bupropion (Wellbutrin XL) 32
Sertraline (Zoloft) 31

Show all 69 treatments patients report switching to

Last updated:

315 patient evaluations for Duloxetine

eman
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eman
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: mild
Upper limb: none
Walking: mild
I am: n
I have:
MS

See eman's full Duloxetine history

May 18, 2010 (Started May 18, 2007)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: No biggie. Easy. worth it.
Cost: < $25 monthly
Side effects: Weight gain

  • 1 helpful mark
Txredhead
25564 thumb
Txredhead
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: All
Sleep: All
Stiffness: All
function: None
external_stress: All
Stickman: all
Description:F55y
FM:26y Dx
CFS:29y Dx
I am: vb
I have:
Fibromyalgia

See Txredhead's full Duloxetine history

Jul 22, 2010 (Started Jun 15, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Dry throat, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta was a like a miracle drug for me when I first started taking it. I can tell if I have forgotten to take it or haven't refilled my script. I highly recommend it for treatment of Fibromyalgia. I still experience some depression, but that is probably normal for someone living in chronic pain.
Cost: $100-199 monthly
Side effects: Dry mouth, Dry throat

  • 1 helpful mark
Babystars
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Babystars
Sex: F
Data Quality: 1 star
Relapse: Moderate
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: none
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See Babystars's full Duloxetine history

Aug 1, 2010 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Pain)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I believe this med was great for me..in order to manage other symptoms as well i was taken off this med and put on another to see if other symptoms were helped.
Cost: < $25 monthly

Aug 20, 2008 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Take it as prescribed and it helps the pain.If you stop taking it for a couple of days you will definitly feel the difference!!So keep taking it.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 315 patient evaluations for Duloxetine