What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,345 2,517
Depressed mood 1,869 1,040
Major Depressive Disorder 1,397 822
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 678 359
Generalized Anxiety Disorder 662 471
Pain 504 285

Show all 321 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 787
Moderate 827
Mild 952
None 1,296

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Nausea 245
Weight gain 232
Sex drive (libido) decreased 152
Dizziness 146
Dry mouth 130
Sweating increased 97

Show all 660 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 323
30 mg daily 132
120 mg daily 72
90 mg daily 56
60 mg twice daily 43
20 mg daily 32
30 mg twice daily 25
40 mg daily 18
120 mg twice daily 6
30 mg three times daily 4

See all 42 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1580
Did not seem to work 1345
Doctor's advice 509
Expense 414
Other 379
Personal research 148
Change in health plan coverage 142
Course of treatment ended 61
See all 3064 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 4
1 - 6 months 48
6 months - 1 year 74
1 - 2 years 126
2 - 5 years 207
5 - 10 years 221
10 years or more 82

Stopped taking Duloxetine

Duration Patients
Less than 1 month 656
1 - 6 months 904
6 months - 1 year 493
1 - 2 years 438
2 - 5 years 445
5 - 10 years 118
10 years or more 26
Adherence
Adherence Evaluations
Always 3252
Usually 347
Sometimes 57
Never taken as prescribed 206
Burden
Burden Evaluations
Very hard to take 240
Somewhat hard to take 306
A little hard to take 471
Not at all hard to take 2845
Cost per month
Cost per month Evaluations
$200+ 116
$100-199 171
$50-99 391
$25-49 594
< $25 1151
Not specified 1439

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 78
Venlafaxine (Effexor XR) 64
Fluoxetine (Prozac) 62
Sertraline (Zoloft) 56
Citalopram (Celexa) 50

Show all 55 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 44
Pregabalin (Lyrica) 36
Bupropion (Wellbutrin XL) 25
Gabapentin (Neurontin) 25
Sertraline (Zoloft) 23

Show all 53 treatments patients report switching to

Last updated:

315 patient evaluations for Duloxetine

3,079 members have decided to share their profiles only with other members of PatientsLikeMe.

eman
14444 thumb
eman
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: mild
Upper limb: none
Walking: mild
I am: n
I have:
MS

See eman's full Duloxetine history

May 18, 2010 (Started May 18, 2007)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: No biggie. Easy. worth it.
Cost: < $25 monthly
Side effects: Weight gain

  • 1 helpful mark
Txredhead
25564 thumb
Txredhead
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: All
Sleep: All
Stiffness: All
function: None
external_stress: All
Stickman: all
Description:F55y
FM:26y Dx
CFS:28y Dx
I am: vb
I have:
Fibromyalgia

See Txredhead's full Duloxetine history

Jul 22, 2010 (Started Jun 15, 2009)

  • Effectiveness
    Major (for Fibromyalgia)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Dry throat, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta was a like a miracle drug for me when I first started taking it. I can tell if I have forgotten to take it or haven't refilled my script. I highly recommend it for treatment of Fibromyalgia. I still experience some depression, but that is probably normal for someone living in chronic pain.
Cost: $100-199 monthly
Side effects: Dry mouth, Dry throat

  • 1 helpful mark
Babystars
1954 thumb
Babystars
Sex: F
Data Quality: 1 star
Relapse: Moderate
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: none
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See Babystars's full Duloxetine history

Aug 1, 2010 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Pain)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I believe this med was great for me..in order to manage other symptoms as well i was taken off this med and put on another to see if other symptoms were helped.
Cost: < $25 monthly

Aug 20, 2008 (Started Jun 03, 2008)

  • Effectiveness
    Moderate (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Take it as prescribed and it helps the pain.If you stop taking it for a couple of days you will definitly feel the difference!!So keep taking it.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 315 patient evaluations for Duloxetine