What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,298 2,485
Depressed mood 1,865 1,037
Major Depressive Disorder 1,376 807
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 678 358
Generalized Anxiety Disorder 659 470
Pain 503 285

Show all 321 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 774
Moderate 822
Mild 939
None 1,278

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Nausea 240
Weight gain 227
Sex drive (libido) decreased 151
Dizziness 145
Dry mouth 128
Sweating increased 97

Show all 657 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 294
30 mg daily 134
120 mg daily 75
90 mg daily 52
60 mg twice daily 43
20 mg daily 31
30 mg twice daily 20
40 mg daily 16
120 mg twice daily 6
20 mg twice daily 3

See all 40 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1570
Did not seem to work 1332
Doctor's advice 509
Expense 412
Other 378
Personal research 148
Change in health plan coverage 141
Course of treatment ended 60
See all 3044 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
1 - 6 months 45
6 months - 1 year 65
1 - 2 years 119
2 - 5 years 198
5 - 10 years 214
10 years or more 78

Stopped taking Duloxetine

Duration Patients
Less than 1 month 645
1 - 6 months 902
6 months - 1 year 491
1 - 2 years 437
2 - 5 years 441
5 - 10 years 118
10 years or more 26
Adherence
Adherence Evaluations
Always 3216
Usually 342
Sometimes 57
Never taken as prescribed 198
Burden
Burden Evaluations
Very hard to take 237
Somewhat hard to take 303
A little hard to take 463
Not at all hard to take 2810
Cost per month
Cost per month Evaluations
$200+ 116
$100-199 170
$50-99 389
$25-49 589
< $25 1127
Not specified 1422

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 73
Venlafaxine (Effexor XR) 61
Fluoxetine (Prozac) 60
Sertraline (Zoloft) 54
Citalopram (Celexa) 47

Show all 55 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 43
Pregabalin (Lyrica) 35
Bupropion (Wellbutrin XL) 24
Gabapentin (Neurontin) 23
Sertraline (Zoloft) 23

Show all 53 treatments patients report switching to

Last updated:

315 patient evaluations for Duloxetine

3,035 members have decided to share their profiles only with other members of PatientsLikeMe.

MakeMeWell
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MakeMeWell
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: Most
Sleep: Some
Stiffness: Some
function: Some
external_stress: Some
Stickman: some
Description:F59y
FM:16y Dx
I am: g
I have:
Fibromyalgia

See MakeMeWell's full Duloxetine history

Jan 22, 2012 (Started Jul 15, 2009)

  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Advice & Tips: I was told to take this medication in the morning instead of at night. After a day or two, I started having strange and weird dreams. They were vivid and scary at times. I would find myself falling out of bed. I fell out of bed several nights that week. I finally got tired of doing that and returned back to taking it at night. The bad dreams stopped and so did the falling out of bed.
Cost: $25-49 monthly

  • 0 helpful marks
Aztek350
41345 thumb
Aztek350
Gender: F
Data Quality: 0 stars
Depression: 2
Mania: 0
Emotional: 1
Anxiety: 0
Compulsion: 1
External Stress: Low
61 F
Function: High
Distress: Low
I am: g
I have:
Persistent depressive disorder (dysthymia)

See Aztek350's full Duloxetine history

Jan 22, 2012 (Started Jul 01, 2010)

  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Constipation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Ladywolf319
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Ladywolf319
Data Quality: 1 star
  • Gender: F
  • Age: 32
Condition: CRPS II 29 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Moderate
I am: vb
I have:
CRPS II

See Ladywolf319's full Duloxetine history

Jan 20, 2012 (Started Dec 09, 2010)

  • Effectiveness
    None (for Fibromyalgia)
  • Effectiveness
    None (for Depressed mood)
  • Effectiveness
    Moderate (for Generalized Anxiety Disorder)
  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Effectiveness
    None (for Pain in upper back)
  • Effectiveness
    None (for Pain in lower abdomen)
  • Side effects
    Mild (Weight gain, Fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly

Dec 27, 2011 (Started Dec 09, 2010)

  • Effectiveness
    Can’t tell (for Fibromyalgia)
  • Effectiveness
    None (for Depressed mood)
  • Effectiveness
    Can’t tell (for Generalized Anxiety Disorder)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Effectiveness
    Can’t tell (for Pain in upper back)
  • Effectiveness
    None (for Pain in lower abdomen)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 315 patient evaluations for Duloxetine