What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,198 2,398
Depressed mood 1,852 1,026
Major Depressive Disorder 1,345 784
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 679 354
Generalized Anxiety Disorder 652 463
Pain 500 280

Show all 321 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 758
Moderate 809
Mild 913
None 1,231

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Nausea 234
Weight gain 220
Sex drive (libido) decreased 151
Dizziness 138
Dry mouth 123
Sweating increased 96

Show all 657 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 249
30 mg daily 112
120 mg daily 65
90 mg daily 49
60 mg twice daily 34
20 mg daily 31
30 mg twice daily 19
40 mg daily 12
120 mg twice daily 5
20 mg twice daily 4

See all 36 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1553
Did not seem to work 1311
Doctor's advice 504
Expense 410
Other 380
Personal research 146
Change in health plan coverage 142
Course of treatment ended 61
See all 3016 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 6
1 - 6 months 49
6 months - 1 year 39
1 - 2 years 87
2 - 5 years 179
5 - 10 years 198
10 years or more 62

Stopped taking Duloxetine

Duration Patients
Less than 1 month 634
1 - 6 months 900
6 months - 1 year 484
1 - 2 years 432
2 - 5 years 437
5 - 10 years 118
10 years or more 26
Adherence
Adherence Evaluations
Always 3138
Usually 331
Sometimes 55
Never taken as prescribed 187
Burden
Burden Evaluations
Very hard to take 228
Somewhat hard to take 293
A little hard to take 455
Not at all hard to take 2735
Cost per month
Cost per month Evaluations
$200+ 114
$100-199 169
$50-99 386
$25-49 580
< $25 1072
Not specified 1390

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 61
Venlafaxine (Effexor XR) 56
Fluoxetine (Prozac) 52
Escitalopram (Lexapro) 47
Sertraline (Zoloft) 47

Show all 53 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 42
Pregabalin (Lyrica) 30
Bupropion (Wellbutrin XL) 23
Sertraline (Zoloft) 22
Gabapentin (Neurontin) 21

Show all 51 treatments patients report switching to

Last updated:

317 patient evaluations for Duloxetine

2,945 members have decided to share their profiles only with other members of PatientsLikeMe.

naebird
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naebird
Gender: F
Data Quality: 0 stars
Pain: Most
Fatigue: All
Sleep: Most
Stiffness: All
function: None
external_stress: All
Stickman: all
Description:F53y
FM:21y Dx
CFS:?y
I am: b
I have:
Fibromyalgia

See naebird's full Duloxetine history

Jan 26, 2012 (Started Mar 15, 2005)

  • Effectiveness
    Can’t tell (for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome)
  • Side effects
    Severe (Feeling sick)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Advice & Tips: i couldnt take it to many side affects.

  • 0 helpful marks
MakeMeWell
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MakeMeWell
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: Most
Sleep: Some
Stiffness: Some
function: Some
external_stress: Some
Stickman: some
Description:F59y
FM:16y Dx
I am: g
I have:
Fibromyalgia

See MakeMeWell's full Duloxetine history

Jan 22, 2012 (Started Jul 15, 2009)

  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Advice & Tips: I was told to take this medication in the morning instead of at night. After a day or two, I started having strange and weird dreams. They were vivid and scary at times. I would find myself falling out of bed. I fell out of bed several nights that week. I finally got tired of doing that and returned back to taking it at night. The bad dreams stopped and so did the falling out of bed.
Cost: $25-49 monthly

  • 0 helpful marks
Aztek350
41345 thumb
Aztek350
Gender: F
Data Quality: 0 stars
Depression: 2
Mania: 0
Emotional: 1
Anxiety: 0
Compulsion: 1
External Stress: Low
61 F
Function: High
Distress: Low
I am: g
I have:
Persistent depressive disorder (dysthymia)

See Aztek350's full Duloxetine history

Jan 22, 2012 (Started Jul 01, 2010)

  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Constipation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 317 patient evaluations for Duloxetine