What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,340 3,198
Depressed mood 2,077 1,226
Major depressive disorder 1,911 1,159
Generalized anxiety disorder 797 568
Myalgic encephalomyelitis/chronic fatigue syndrome 693 385
Pain 533 314

Show all 326 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 928
Moderate 1,014
Mild 1,144
None 1,762

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 334
Nausea 287
Decreased sex drive (libido) 184
Dry mouth 169
Dizziness 159
Sweating increased 100

Show all 733 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 433
30 mg daily 167
120 mg daily 140
90 mg daily 72
60 mg twice daily 71
20 mg daily 60
30 mg twice daily 30
40 mg daily 15
20 mg twice daily 13
120 mg twice daily 13

See all 46 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1748
Did not seem to work 1547
Doctor's advice 582
Expense 443
Other 433
Personal research 174
Change in health plan coverage 160
Course of treatment ended 69
See all 3479 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 1
1 - 6 months 34
6 months - 1 year 88
1 - 2 years 145
2 - 5 years 309
5 - 10 years 340
10 years or more 168

Stopped taking Duloxetine

Duration Patients
Less than 1 month 814
1 - 6 months 933
6 months - 1 year 548
1 - 2 years 495
2 - 5 years 515
5 - 10 years 155
10 years or more 35
Adherence
Adherence Evaluations
Always 4055
Usually 431
Sometimes 75
Never taken as prescribed 287
Burden
Burden Evaluations
Very hard to take 300
Somewhat hard to take 369
A little hard to take 574
Not at all hard to take 3605
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 191
$50-99 434
$25-49 691
< $25 1559
Not specified 1847

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 129
Venlafaxine (Effexor XR) 123
Sertraline (Zoloft) 111
Citalopram (Celexa) 97

Show all 74 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 77
Venlafaxine (Effexor XR) 69
Gabapentin (Neurontin) 58
Escitalopram (Lexapro) 37
Bupropion (Wellbutrin XL) 36

Show all 77 treatments patients report switching to

Last updated:

320 patient evaluations for Duloxetine

Feb 14, 2012 (Started Jun 30, 2008)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I find this helps, some BUT I have to take it in the evening because it makes me CRAZY nauseous in the morning. Also if I take it within 4 hours of sleeping I get horrible NIGHTMARES, like half awake/half asleep, screaming nightmares that I can't wake from. Also, I can't take more than 30mg a day or my eyes will swell! Very rare side effect, but if you take this and notice a change in your vision, call your dr asap!
Cost: $50-99 monthly

  • 0 helpful marks

Feb 13, 2012 (Started Sep 07, 2009)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Feb 5, 2012 (Started Aug 01, 2011)

  • Effectiveness
    Slight (for diabetic neuropathy)
  • Side effects
    Mild (muscle fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 320 patient evaluations for Duloxetine