What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,276 3,157
Depressed mood 2,046 1,190
Major depressive disorder 1,853 1,123
Generalized anxiety disorder 785 550
Myalgic encephalomyelitis/chronic fatigue syndrome 696 386
Pain 531 309

Show all 314 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
916
Moderate
998
Mild
1,130
None
1,711

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 313
Nausea 284
Dry mouth 166
Dizziness 158
Decreased sex drive (libido) 151
Sweating increased 100

Show all 745 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 431
30 mg daily 177
120 mg daily 127
90 mg daily 82
60 mg twice daily 68
20 mg daily 66
30 mg twice daily 40
40 mg daily 26
120 mg twice daily 20
20 mg twice daily 17

See all 47 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1730
Did not seem to work 1521
Doctor's advice 570
Expense 443
Other 423
Personal research 168
Change in health plan coverage 158
Course of treatment ended 69
See all 3427 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 8
1 - 6 months 85
6 months - 1 year 76
1 - 2 years 173
2 - 5 years 329
5 - 10 years 340
10 years or more 136

Stopped taking Duloxetine

Duration Patients
Less than 1 month 748
1 - 6 months 961
6 months - 1 year 558
1 - 2 years 487
2 - 5 years 506
5 - 10 years 151
10 years or more 33
Adherence
Adherence Evaluations
Always 3985
Usually 419
Sometimes 73
Never taken as prescribed 278
Burden
Burden Evaluations
Very hard to take 296
Somewhat hard to take 364
A little hard to take 551
Not at all hard to take 3544
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 191
$50-99 431
$25-49 685
< $25 1537
Not specified 1785

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 153
Fluoxetine (Prozac) 122
Venlafaxine (Effexor XR) 116
Sertraline (Zoloft) 105
Citalopram (Celexa) 95

Show all 74 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 77
Venlafaxine (Effexor XR) 67
Gabapentin (Neurontin) 57
Sertraline (Zoloft) 36
Bupropion (Wellbutrin XL) 35

Show all 76 treatments patients report switching to

Last updated:

318 patient evaluations for Duloxetine

Feb 3, 2012 (Started Jul 01, 2010)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    Mild (migraine headaches)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Jan 27, 2012 (Started Sep 03, 2008)

  • Effectiveness
    Moderate (for Pain)
  • Effectiveness
    None (for depressed mood)
  • Side effects
    Moderate (dry mouth)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I was too nice, easily taken at advantage off.
Cost: < $25 monthly

Jul 6, 2009 (Started Sep 03, 2008)

  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 60 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Jan 26, 2012 (Started Mar 15, 2005)

  • Effectiveness
    Can’t tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    Severe (feeling sick)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Advice & Tips: i couldnt take it to many side affects.

  • 0 helpful marks
Last updated:
Showing 3 of 318 patient evaluations for Duloxetine