What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,776 2,806
Depressed mood 1,933 1,088
Major Depressive Disorder 1,575 951
Generalized Anxiety Disorder 701 492
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 684 368
Pain 516 290

Show all 341 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 842
Moderate 890
Mild 1,033
None 1,495

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Nausea 269
Weight gain 259
Dizziness 157
Sex drive (libido) decreased 153
Dry mouth 145
Sweating increased 98

Show all 704 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 453
30 mg daily 183
120 mg daily 105
60 mg twice daily 87
90 mg daily 85
20 mg daily 66
30 mg twice daily 47
40 mg daily 31
120 mg twice daily 23
40 mg twice daily 8

See all 56 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1645
Did not seem to work 1420
Doctor's advice 533
Expense 424
Other 403
Personal research 157
Change in health plan coverage 150
Course of treatment ended 63
See all 3216 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 13
1 - 6 months 95
6 months - 1 year 142
1 - 2 years 202
2 - 5 years 311
5 - 10 years 308
10 years or more 126

Stopped taking Duloxetine

Duration Patients
Less than 1 month 696
1 - 6 months 929
6 months - 1 year 521
1 - 2 years 461
2 - 5 years 469
5 - 10 years 127
10 years or more 29
Adherence
Adherence Evaluations
Always 3584
Usually 372
Sometimes 63
Never taken as prescribed 241
Burden
Burden Evaluations
Very hard to take 263
Somewhat hard to take 331
A little hard to take 503
Not at all hard to take 3163
Cost per month
Cost per month Evaluations
$200+ 118
$100-199 179
$50-99 407
$25-49 635
< $25 1339
Not specified 1582

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 115
Fluoxetine (Prozac) 88
Venlafaxine (Effexor XR) 84
Sertraline (Zoloft) 76
Citalopram (Celexa) 62

Show all 62 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 54
Venlafaxine (Effexor XR) 53
Gabapentin (Neurontin) 34
Sertraline (Zoloft) 29
Bupropion (Wellbutrin XL) 27

Show all 66 treatments patients report switching to

Last updated:

316 patient evaluations for Duloxetine

3,438 members have decided to share their profiles only with other members of PatientsLikeMe.

MakeMeWell
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MakeMeWell
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: Most
Sleep: Some
Stiffness: Some
function: Some
external_stress: Some
Stickman: some
Description:F59y
FM:16y Dx
I am: g
I have:
Fibromyalgia

See MakeMeWell's full Duloxetine history

Jan 22, 2012 (Started Jul 15, 2009)

  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Advice & Tips: I was told to take this medication in the morning instead of at night. After a day or two, I started having strange and weird dreams. They were vivid and scary at times. I would find myself falling out of bed. I fell out of bed several nights that week. I finally got tired of doing that and returned back to taking it at night. The bad dreams stopped and so did the falling out of bed.
Cost: $25-49 monthly

  • 0 helpful marks
Aztek350
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Aztek350
Gender: F
Data Quality: 1 star
Depression: 2
Mania: 0
Emotional: 1
Anxiety: 0
Compulsion: 1
External Stress: Low
61 F
Function: High
Distress: Low
I am: g
I have:
Persistent depressive disorder (dysthymia)

See Aztek350's full Duloxetine history

Jan 22, 2012 (Started Jul 01, 2010)

  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • Side effects
    Mild (Constipation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Ladywolf319
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Ladywolf319
Data Quality: 1 star
  • Gender: F
  • Age: 32
Condition: CRPS II 29 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Moderate
I am: vb
I have:
CRPS II

See Ladywolf319's full Duloxetine history

Jan 20, 2012 (Started Dec 09, 2010)

  • Effectiveness
    None (for Fibromyalgia)
  • Effectiveness
    None (for Depressed mood)
  • Effectiveness
    Moderate (for Generalized Anxiety Disorder)
  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Effectiveness
    None (for Pain in upper back)
  • Effectiveness
    None (for Pain in lower abdomen)
  • Side effects
    Mild (Weight gain, Fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly

Dec 27, 2011 (Started Dec 09, 2010)

  • Effectiveness
    Can’t tell (for Fibromyalgia)
  • Effectiveness
    None (for Depressed mood)
  • Effectiveness
    Can’t tell (for Generalized Anxiety Disorder)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Effectiveness
    Can’t tell (for Pain in upper back)
  • Effectiveness
    None (for Pain in lower abdomen)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 316 patient evaluations for Duloxetine