What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,180 3,115
Depressed mood 2,023 1,174
Major depressive disorder 1,812 1,103
Generalized anxiety disorder 779 543
Myalgic encephalomyelitis/chronic fatigue syndrome 695 381
Pain 525 305

Show all 315 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 904
Moderate 986
Mild 1,118
None 1,682

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 304
Nausea 281
Dry mouth 160
Dizziness 155
Sex drive (libido) decreased 151
Sweating increased 100

Show all 727 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 409
30 mg daily 171
120 mg daily 122
60 mg twice daily 78
90 mg daily 75
20 mg daily 60
30 mg twice daily 40
40 mg daily 29
120 mg twice daily 17
20 mg twice daily 14

See all 45 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1711
Did not seem to work 1503
Doctor's advice 568
Expense 443
Other 419
Personal research 168
Change in health plan coverage 158
Course of treatment ended 68
See all 3389 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 2
1 - 6 months 75
6 months - 1 year 97
1 - 2 years 178
2 - 5 years 334
5 - 10 years 302
10 years or more 122

Stopped taking Duloxetine

Duration Patients
Less than 1 month 737
1 - 6 months 955
6 months - 1 year 553
1 - 2 years 483
2 - 5 years 501
5 - 10 years 144
10 years or more 33
Adherence
Adherence Evaluations
Always 3936
Usually 413
Sometimes 68
Never taken as prescribed 273
Burden
Burden Evaluations
Very hard to take 295
Somewhat hard to take 359
A little hard to take 545
Not at all hard to take 3491
Cost per month
Cost per month Evaluations
$200+ 125
$100-199 190
$50-99 429
$25-49 676
< $25 1512
Not specified 1758

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 150
Fluoxetine (Prozac) 117
Venlafaxine (Effexor XR) 112
Sertraline (Zoloft) 93
Citalopram (Celexa) 90

Show all 71 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 75
Venlafaxine (Effexor XR) 62
Gabapentin (Neurontin) 54
Sertraline (Zoloft) 35
Bupropion (Wellbutrin XL) 33

Show all 74 treatments patients report switching to

Last updated:

318 patient evaluations for Duloxetine

Jan 27, 2012 (Started Sep 03, 2008)

  • Effectiveness
    Moderate (for pain)
  • Effectiveness
    None (for depressed mood)
  • Side effects
    Moderate (dry mouth)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I was too nice, easily taken at advantage off.
Cost: < $25 monthly

Jul 6, 2009 (Started Sep 03, 2008)

  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 60 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Jan 26, 2012 (Started Mar 15, 2005)

  • Effectiveness
    Can’t tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    Severe (feeling sick)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Advice & Tips: i couldnt take it to many side affects.

  • 0 helpful marks

Jan 22, 2012 (Started Jul 15, 2009)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Advice & Tips: I was told to take this medication in the morning instead of at night. After a day or two, I started having strange and weird dreams. They were vivid and scary at times. I would find myself falling out of bed. I fell out of bed several nights that week. I finally got tired of doing that and returned back to taking it at night. The bad dreams stopped and so did the falling out of bed.
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 318 patient evaluations for Duloxetine