What is Promethazine?

Category: Prescription Drugs

Most popular types: Phenergan Promethegan Phenadoz Show all

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See also: Promethazine DM

Promethazine is an antiemetic and antihistamine. It is used to relieve the symptoms of allergic reactions, nausea, motion sickness. It is also use as a sedative, as adjunctive therapy for postoperative pain, anesthetic and anaphylactic reactions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Nausea 263 81
Gastroparesis 52 15
Migraine headaches 39 16
Insomnia 17 5
Anxious mood 9 5

Show all 61 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 11
Moderate 30
Mild 61
None 78

Commonly reported side effects and conditions associated with Promethazine

Side effect Patients
Drowsiness 34
Sleepiness 10
Excessive daytime sleepiness (somnolence) 6
Fatigue 6
Tiredness 5
Blurry vision 2

Show all 35 reported side effects

Dosages

Based on patients currently taking Promethazine

Dosage Patients
25mg as needed 27
25mg/mL as needed 6
25 mg daily 1
50 mg daily 3
50mg as needed 3
12.5mg as needed 2
1 tablet(s) daily 1
25 mg weekly 1
12.5 mg four times daily 1

See all 21 dosages

Why patients stopped taking Promethazine

Multiple reasons could be selected

Reason Patients
Course of treatment ended 36
Doctor's advice 31
Other 28
Did not seem to work 26
Side effects too severe 24
Change in health plan coverage 3
Expense 1
See all 122 patients who've stopped taking Promethazine

Duration

Currently taking Promethazine

Duration Patients
6 months - 1 year 2
1 - 2 years 4
2 - 5 years 15
5 - 10 years 28
10 years or more 14

Stopped taking Promethazine

Duration Patients
Less than 1 month 35
1 - 6 months 21
6 months - 1 year 16
1 - 2 years 17
2 - 5 years 19
5 - 10 years 9
10 years or more 7
Adherence
Adherence Evaluations
Always 116
Usually 31
Sometimes 27
Never taken as prescribed 6
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 9
A little hard to take 19
Not at all hard to take 149
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 0
$50-99 0
$25-49 5
< $25 89
Not specified 83

What people switch to and from

Patients started taking Promethazine after stopping:

Treatment Patients
Ondansetron (Zofran) 14
Meclizine (Antivert) 2
Prochlorperazine (Compazine) 2
Carbamazepine (Tegretol) 1
Gabapentin (Neurontin) 1

Show all 8 treatments patients report switching from

Patients stopped taking Promethazine and switched to:

Treatment Patients
Ondansetron (Zofran) 21
Prochlorperazine (Compazine) 3
Cetirizine-pseudoephedrine (Zyrtec-D) 1
Medical marijuana (Cannabidiol/Tetrahydrocannabinol Balanced Mixture) 1
Rizatriptan (Maxalt) 1

Show all 6 treatments patients report switching to

Last updated:

19 patient evaluations for Promethazine

Apr 6, 2018 (Started Mar 01, 2017)

  • Effectiveness
    Major (for nausea)
  • Side effects
    Mild (drowsiness, restless legs syndrome)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Feb 15, 2016 (Started Sep 26, 2015)

  • Effectiveness
    Major (for nausea and vomiting)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Dec 1, 2015 (Started Feb 24, 2011)

  • Effectiveness
    Moderate (for nausea and vomiting)
  • Effectiveness
    Moderate (for nausea)
  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 19 patient evaluations for Promethazine