What is Wiley protocol HRT?

Category: Prescription Drugs


See also: Estradiol topical

The Wiley Protocol® is a hormone replacement therapy (HRT) delivery system. It consists of estradiol and progesterone in a topical cream preparation. The doses of the two medications varies over the 28 day cycle of the protocol.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 0
Moderate 0
Mild 1
None 0

Commonly reported side effects and conditions associated with Wiley protocol HRT

Side effect Patients
Breast tenderness 1
Adherence Evaluations
Always 1
Usually 0
Sometimes 0
Never taken as prescribed 0
Burden Evaluations
Very hard to take 0
Somewhat hard to take 0
A little hard to take 0
Not at all hard to take 1
Last updated:
There are no evaluations for Wiley protocol HRT.