What is Interferon beta-1a SubQ injection?

Category: Prescription Drugs

Most popular types: Rebif Rebif Rebidose

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Interferon beta-1a is an immunomodulator used to prevent episodes of symptoms and slow the development of disability in patients with relapsing-remitting multiple sclerosis. It comes as a solution to inject subcutaneously (under the skin) three times a week, ideally the same 3 days each week.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 2,970 1,365
Stiffness/spasticity 35 27
Fatigue 26 5
General health 16 12
Improve mobility 9 4
Balance problems 4 2

Show all 35 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
267
Moderate
436
Mild
493
None
194

Commonly reported side effects and conditions associated with Interferon beta-1a SubQ injection

Side effect Patients
Injection site redness 176
Flu like symptoms 159
Headaches 159
Muscle aches 154
Fever/chills 134
Injection site pain 103

Show all 316 reported side effects

Dosages

Based on patients currently taking Interferon beta-1a SubQ injection

Dosage Patients
44 mcg/0.5 mL 3 times a week 45
44 mcg 3 times a week 20
22 mcg/0.5 mL 3 times a week 8
3 x 44 mcg/0.5 mL weekly 6
44 mcg/0.5 mL daily 5
44 mcg/0.5 mL weekly 4
44 mcg/0.5 mL m,w,f 4
44 mcg m,w,f 4
22 mcg/0.5 mL m,w,f 3
30 mcg 3 times a week 3

See all 36 dosages

Why patients stopped taking Interferon beta-1a SubQ injection

Multiple reasons could be selected

Reason Patients
Side effects too severe 754
Did not seem to work 502
Doctor's advice 447
Other 303
Expense 83
Personal research 69
Course of treatment ended 33
Change in health plan coverage 30
See all 1549 patients who've stopped taking Interferon beta-1a SubQ injection

Duration

Currently taking Interferon beta-1a SubQ injection

Duration Patients
1 - 6 months 1
6 months - 1 year 2
1 - 2 years 7
2 - 5 years 28
5 - 10 years 53
10 years or more 48

Stopped taking Interferon beta-1a SubQ injection

Duration Patients
Less than 1 month 94
1 - 6 months 311
6 months - 1 year 264
1 - 2 years 301
2 - 5 years 393
5 - 10 years 162
10 years or more 32
Adherence
Adherence Evaluations
Always 1095
Usually 211
Sometimes 32
Never taken as prescribed 52
Burden
Burden Evaluations
Very hard to take 166
Somewhat hard to take 385
A little hard to take 436
Not at all hard to take 403
Cost per month
Cost per month Evaluations
$200+ 77
$100-199 49
$50-99 201
$25-49 253
< $25 426
Not specified 384

What people switch to and from

Patients started taking Interferon beta-1a SubQ injection after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 30
Interferon beta-1a IM Injection (Avonex) 25
Dimethyl fumarate (Tecfidera) 7
Interferon beta-1b SubQ Injection (Betaseron) 6
Teriflunomide (Aubagio) 5

Show all 14 treatments patients report switching from

Patients stopped taking Interferon beta-1a SubQ injection and switched to:

Treatment Patients
Dimethyl fumarate (Tecfidera) 45
Glatiramer acetate (Copaxone) 39
Natalizumab (Tysabri) 35
Fingolimod (Gilenya) 33
Teriflunomide (Aubagio) 11

Show all 16 treatments patients report switching to

Last updated:

129 patient evaluations for Interferon beta-1a SubQ injection

Aug 31, 2016 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: $50-99 monthly

Jul 29, 2011 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: $25-49 monthly

Jun 15, 2010 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Advice & Tips: I do my shots Sun, Tues, Thurs. After the first 6 months or so I had no more reactions at all. I can do the shot and then do whatever I had planned. I find that doing the shot freehand is much easier after the initial shock of actually sticking the needle in goes by. Now it is just something I do.
Cost: < $25 monthly

May 21, 2010 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: < $25 monthly

Oct 29, 2009 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: < $25 monthly

Sep 23, 2009 (Started Feb 24, 2009)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 44 mcg/0.5 mL Weekly
Cost: < $25 monthly

  • 0 helpful marks

Apr 20, 2016 (Started May 07, 2004)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Cost: < $25 monthly
Side effects: fatigue, fatigue

Jul 10, 2015 (Started May 07, 2004)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (fatigue)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: I am taking therapy in till noon, or according my work load Still working, traveling, walking minor impact, don't think about illness constantly
Cost: < $25 monthly
Side effects: fatigue, fatigue

Aug 7, 2010 (Started May 07, 2004)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: because of side effects i take injection 12-20h before major workload
Side effects: fatigue, fatigue

  • 0 helpful marks

Nov 10, 2015 (Started Sep 01, 2006)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (pressure headaches)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: Injection site reactions have not resolved and I am discontinuing Rebif. Starting Tecfidera as of tonight.
Cost: $50-99 monthly
Side effects: pressure headaches

Nov 3, 2015 (Started Sep 01, 2006)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (pressure headaches)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: Site reaction issues causing stop.
Cost: $50-99 monthly
Side effects: pressure headaches

Oct 16, 2015 (Started Sep 01, 2006)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (pressure headaches)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: Issues with site getting worse. Scaley, itchy, legs showing the same reactions although I haven't used those sites in years. We're going to participate in a two year Ticfidera trial.
Cost: $50-99 monthly
Side effects: pressure headaches

Aug 18, 2015 (Started Sep 01, 2006)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (pressure headaches)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Advice & Tips: Only side I have is headache and stiffness. Not a problem If I take NSAID before injection prior to bed. Currently having site injection reactions that have become a large problem.
Cost: $50-99 monthly
Side effects: pressure headaches

Sep 15, 2010 (Started Sep 01, 2006)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (pressure headaches)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 44 mcg/0.5 mL 3 times a week
Cost: $25-49 monthly
Side effects: pressure headaches

  • 0 helpful marks
Last updated:
Showing 3 of 129 patient evaluations for Interferon beta-1a SubQ injection