What is Sertraline?

Category: Prescription Drugs

Most popular types: Zoloft Apo-Sertraline Lustral Show all

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Sertraline, a selective serotonin reuptake inhibitor (SSRI) antidepressant, is used in the treatment of major depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 1,563 701
Major Depressive Disorder 1,201 591
Post-traumatic stress disorder 540 279
Anxious mood 472 192
Panic Disorder 254 137
Persistent depressive disorder (dysthymia) 163 115

Show all 202 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 195
Moderate 364
Mild 396
None 620

Commonly reported side effects and conditions associated with Sertraline

Side effect Patients
Weight gain 96
Dry mouth 69
Sex drive (libido) decreased 63
Loss of sex drive (libido) 58
Fatigue 56
Insomnia 41

Show all 324 reported side effects

Dosages

Based on patients currently taking Sertraline

Dosage Patients
100 mg daily 125
50 mg daily 91
200 mg daily 61
150 mg daily 53
25 mg daily 39
75 mg daily 11
100 mg twice daily 9
20 mg daily 6
50 mg twice daily 6
25 mg twice daily 2

See all 29 dosages

Why patients stopped taking Sertraline

Multiple reasons could be selected

Reason Patients
Did not seem to work 614
Side effects too severe 414
Doctor's advice 356
Other 243
Course of treatment ended 81
Personal research 68
Expense 54
Change in health plan coverage 41
See all 1312 patients who’ve stopped taking Sertraline

Duration

Currently taking Sertraline

Duration Patients
Less than 1 month 2
1 - 6 months 50
6 months - 1 year 38
1 - 2 years 58
2 - 5 years 122
5 - 10 years 85
10 years or more 78

Stopped taking Sertraline

Duration Patients
Less than 1 month 203
1 - 6 months 302
6 months - 1 year 199
1 - 2 years 201
2 - 5 years 228
5 - 10 years 125
10 years or more 65
Adherence
Adherence Evaluations
Always 1232
Usually 239
Sometimes 55
Never taken as prescribed 49
Burden
Burden Evaluations
Very hard to take 64
Somewhat hard to take 105
A little hard to take 246
Not at all hard to take 1160
Cost per month
Cost per month Evaluations
$200+ 6
$100-199 16
$50-99 18
$25-49 71
< $25 795
Not specified 669

What people switch to and from

Patients started taking Sertraline after stopping:

Treatment Patients
Fluoxetine (Prozac) 49
Citalopram (Celexa) 44
Bupropion (Wellbutrin XL) 26
Duloxetine (Cymbalta) 21
Venlafaxine (Effexor XR) 20

Show all 42 treatments patients report switching from

Patients stopped taking Sertraline and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 36
Bupropion (Wellbutrin XL) 33
Duloxetine (Cymbalta) 32
Escitalopram (Lexapro) 25
Fluoxetine (Prozac) 23

Show all 30 treatments patients report switching to

Last updated:

142 patient evaluations for Sertraline

1,208 members have decided to share their profiles only with other members of PatientsLikeMe.

MSMomx4
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MSMomx4
Sex: F
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See MSMomx4's full Sertraline history

Nov 30, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes since 3/20/15
Cost: < $25 monthly

Aug 2, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 9, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Apr 24, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 1, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Oct 21, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 20, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: My digestive problems have been resolved. I have no other conditions that would lead a doctor to think I had anything seriously wrong with me. I now take 150 mgs of Zoloft. I take it every day with no problem.
Cost: < $25 monthly

Feb 4, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: The only problem I've had is bad diarhea, from starting to take it again after not having been on it for about a month. This was due to a change in providers.
Cost: < $25 monthly

Oct 28, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 10, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I am now taking 200 mg a day (4 50mg tabs a day). I have no problems with taking it at all.
Cost: < $25 monthly

Jun 2, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 8, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Jan 17, 2011 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: it has had no impact on my lifestyle at all. It is a pill taken once a day.
Cost: < $25 monthly

  • 0 helpful marks
Haruka
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new ASD member
Data Quality: 3 stars
21 years
vg
ATEC
  • Speech: 0
  • Sociability: 11
  • Sensory/Cognitive Awareness: 3
  • Health/Physical Behavior: 14
  • ATEC score: 28
I have:
Autism

See Haruka's full Sertraline history

Sep 29, 2016 (Started Jun 30, 2008)

  • Effectiveness
    Can’t tell (for Post-traumatic stress disorder)
  • Effectiveness
    Can’t tell (for Panic attacks)
  • Effectiveness
    Major (for Insomnia)
  • Effectiveness
    Can’t tell (for Depressed mood)
  • Effectiveness
    Can’t tell (for ASD (Autism Spectrum Disorder))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily

Aug 6, 2014 (Started Jun 30, 2008)

  • Effectiveness
    Major (for Post-traumatic stress disorder)
  • Effectiveness
    Major (for Insomnia)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for ASD (Autism Spectrum Disorder))
  • Effectiveness
    Major (for Panic attacks)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: can't sleep without it

Jul 1, 2008 (Started Jun 30, 2008)

  • Effectiveness
    Slight (for Insomnia)
  • Effectiveness
    Major (for ASD (Autism Spectrum Disorder))
  • Effectiveness
    Major (for Post-traumatic stress disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: works for me

  • 1 helpful mark
25yrRA
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25yrRA
Data Quality: 2 stars
  • Gender: F
  • Age: 55
Condition: Rheumatoid Arthritis (RA) 20 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: n
I have:
Rheumatoid Arthritis (RA)

See 25yrRA's full Sertraline history

Aug 21, 2016 (Started Sep 01, 2008)

  • Effectiveness
    Major (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Major (for Panic Disorder)
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Effectiveness
    Major (for Generalized Anxiety Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: A long time friend as far as meds go. It has been my major depression med for many years. I feel very comfortable with it, but have experienced what I best describe as breakthrough depression for the last 4 to 5 years and have taken it with adjunct meds, i.e. Abilify and currently Seroquel XR.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 142 patient evaluations for Sertraline