What is Sertraline?

Category: Prescription Drugs

Most popular types: Zoloft Apo-Sertraline Sertra Show all

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Sertraline, a selective serotonin reuptake inhibitor (SSRI) antidepressant, is used in the treatment of major depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 1,829 907
Major depressive disorder 1,627 877
Post-traumatic stress disorder 741 437
Anxious mood 493 216
Panic disorder 320 200
Persistent depressive disorder (dysthymia) 214 158

Show all 191 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
255
Moderate
450
Mild
531
None
835

Commonly reported side effects and conditions associated with Sertraline

Side effect Patients
Weight gain 130
Dry mouth 80
Decreased sex drive (libido) 77
Fatigue 71
Loss of sex drive (libido) 71
Nausea 51

Show all 393 reported side effects

Dosages

Based on patients currently taking Sertraline

Dosage Patients
100 mg daily 183
50 mg daily 135
200 mg daily 73
150 mg daily 62
25 mg daily 49
100 mg twice daily 22
75 mg daily 11
50 mg twice daily 8
20 mg daily 4
300 mg daily 4

See all 38 dosages

Why patients stopped taking Sertraline

Multiple reasons could be selected

Reason Patients
Did not seem to work 765
Side effects too severe 509
Doctor's advice 439
Other 284
Course of treatment ended 95
Personal research 84
Expense 60
Change in health plan coverage 45
See all 1593 patients who've stopped taking Sertraline

Duration

Currently taking Sertraline

Duration Patients
1 - 6 months 26
6 months - 1 year 47
1 - 2 years 103
2 - 5 years 151
5 - 10 years 139
10 years or more 123

Stopped taking Sertraline

Duration Patients
Less than 1 month 282
1 - 6 months 321
6 months - 1 year 249
1 - 2 years 236
2 - 5 years 284
5 - 10 years 139
10 years or more 94
Adherence
Adherence Evaluations
Always 1622
Usually 298
Sometimes 71
Never taken as prescribed 80
Burden
Burden Evaluations
Very hard to take 81
Somewhat hard to take 138
A little hard to take 302
Not at all hard to take 1550
Cost per month
Cost per month Evaluations
$200+ 8
$100-199 20
$50-99 19
$25-49 78
< $25 1043
Not specified 903

What people switch to and from

Patients started taking Sertraline after stopping:

Treatment Patients
Fluoxetine (Prozac) 99
Citalopram (Celexa) 80
Bupropion (Wellbutrin XL) 61
Venlafaxine (Effexor XR) 49
Duloxetine (Cymbalta) 35

Show all 53 treatments patients report switching from

Patients stopped taking Sertraline and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 72
Duloxetine (Cymbalta) 65
Bupropion (Wellbutrin XL) 62
Fluoxetine (Prozac) 53
Escitalopram (Lexapro) 50

Show all 43 treatments patients report switching to

Last updated:

147 patient evaluations for Sertraline

Feb 14, 2018 (Started Jan 25, 2018)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Side effects
    Moderate (diarrhea, exhaustion, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: I was still breastfeeding when I was on this. I quit taking it when my baby started experiencing the same side effects as I was. Apparently it can pass through the breastmilk in enough concentration to adversely affect my baby's physical health. Not worth it.
Cost: < $25 monthly

  • 0 helpful marks

Oct 2, 2017 (Started Feb 16, 2014)

  • Effectiveness
    Moderate (for mild depression)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Aug 1, 2015 (Started Feb 16, 2014)

  • Effectiveness
    Major (for mild depression)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: I found that taking Sertraline was much more effective than any other Anti Depressants i have taken. My reason for stopping was to try and ascertain whether or not it was causing another Medical disorder, NIGHT SWEATING. IF the Night Sweating persists without the Sertraline i will probably go back to Sertraline
Cost: < $25 monthly

Feb 4, 2015 (Started Feb 16, 2014)

  • Effectiveness
    Moderate (for mild depression)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily

  • 1 helpful mark

Feb 15, 2017 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes
Cost: < $25 monthly

Nov 30, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes since 3/20/15
Cost: < $25 monthly

Aug 2, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 9, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Apr 24, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 1, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Oct 21, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 20, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: My digestive problems have been resolved. I have no other conditions that would lead a doctor to think I had anything seriously wrong with me. I now take 150 mgs of Zoloft. I take it every day with no problem.
Cost: < $25 monthly

Feb 4, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: The only problem I've had is bad diarhea, from starting to take it again after not having been on it for about a month. This was due to a change in providers.
Cost: < $25 monthly

Oct 28, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 10, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I am now taking 200 mg a day (4 50mg tabs a day). I have no problems with taking it at all.
Cost: < $25 monthly

Jun 2, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 8, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Jan 17, 2011 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: it has had no impact on my lifestyle at all. It is a pill taken once a day.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 147 patient evaluations for Sertraline