What is Methotrexate injections?

Category: Prescription Drugs

Most popular types: Metoject Intrathecal Methotrexate Otrexup Show all

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Methotrexate is an antineoplastic drug used in the treatment of cancer. Also used as an antirheumatic for rheumatoid arthritis. It may also be used in treatment of Crohn's disease, ectopic pregnancy, or MS. It is given by mouth, by injection, via IV or intrathecally.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 21 11
Systemic lupus erythematosus 7 4
Crohn's disease 3 1
Psoriatic arthritis 3 1
Multiple sclerosis 2 2
Dermatomyositis 1 0

Show all 14 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 6
Moderate 5
Mild 8
None 3

Commonly reported side effects and conditions associated with Methotrexate injections

Side effect Patients
Nausea 5
Fatigue 2
Headaches 2
Mouth sores (ulcers) 2
Abdominal pain 1
Blood in stool 1

Show all 19 reported side effects

Dosages

Based on patients currently taking Methotrexate injections

Dosage Patients
25 mg weekly 8
5 mg weekly 2
10 mg weekly 2
15 mg weekly 2
20 mg weekly 2
0.5 mL weekly 1
0.6 mL weekly 1
1 mL weekly 1
4 tablet(s) weekly 1
12.5 mg weekly 1

See all 13 dosages

Why patients stopped taking Methotrexate injections

Multiple reasons could be selected

Reason Patients
Side effects too severe 5
Did not seem to work 4
Doctor's advice 3
Change in health plan coverage 2
Other 1
Personal research 1
See all 10 patients who've stopped taking Methotrexate injections

Duration

Currently taking Methotrexate injections

Duration Patients
1 - 6 months 4
6 months - 1 year 4
1 - 2 years 4
2 - 5 years 7
5 - 10 years 5
10 years or more 1

Stopped taking Methotrexate injections

Duration Patients
Less than 1 month 1
1 - 6 months 3
6 months - 1 year 3
1 - 2 years 2
2 - 5 years 1
Adherence
Adherence Evaluations
Always 18
Usually 1
Sometimes 0
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 4
A little hard to take 8
Not at all hard to take 8
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 1
$50-99 0
$25-49 1
< $25 11
Not specified 9

What people switch to and from

Patients started taking Methotrexate injections after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 10
Adalimumab (Humira) 1
Hydroxychloroquine (Plaquenil) 1
Vitamin B12 Injection (Medivitan) 1

Patients stopped taking Methotrexate injections and switched to:

Treatment Patients
Sulfasalazine (Salazopyrin) 2
Adalimumab (Humira) 1
Azathioprine (Imuran) 1
Methotrexate (Apo-Methotrexate) 1
Methylprednisolone (Solu-Medrol Infusion) 1

Show all 6 treatments patients report switching to

Last updated:
There are no evaluations for Methotrexate injections.