What is asenapine?

Category: Prescription Drugs

Most popular types: Saphris Sycrest

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Asenapine is an atypical antipsychotic used for acute treatment of schizophrenia in adults and acute treatment of manic or mixed episodes associated with bipolar I disorder in adults. It is available as a tablet that should be dissolved underneath the tongue two times per day.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 57 52
Bipolar I Disorder 37 16
Major Depressive Disorder 20 20
Bipolar II Disorder 8 11
Schizoaffective Disorder 5 3
Schizophrenia 5 13

Show all 42 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 42
Moderate 19
Mild 22
None 21

Commonly reported side effects and conditions associated with asenapine

Side effect Patients
Weight gain 15
Numbness in tongue 4
Bad taste in mouth 3
Increased appetite 3
Nausea 3
Restlessness (akathisia) 3

Show all 76 reported side effects

Dosages

Based on patients currently taking asenapine

Dosage Patients
10 mg daily 9
5 mg twice daily 4
5 mg daily 3
20 mg daily 3
1 tablet(s) daily 2
2.5 mg daily 2
1 mg daily 1
1 other daily 1
1 tablet(s) twice daily 1
15 mg daily 1

See all 11 dosages

Why patients stopped taking asenapine

Multiple reasons could be selected

Reason Patients
Side effects too severe 41
Did not seem to work 18
Doctor's advice 12
Other 11
Expense 6
Personal research 4
Course of treatment ended 2
See all 69 patients who’ve stopped taking asenapine

Duration

Currently taking asenapine

Duration Patients
Less than 1 month 2
1 - 6 months 5
6 months - 1 year 1
1 - 2 years 11
2 - 5 years 5
5 - 10 years 4

Stopped taking asenapine

Duration Patients
Less than 1 month 26
1 - 6 months 22
6 months - 1 year 10
1 - 2 years 8
2 - 5 years 3
Adherence
Adherence Evaluations
Always 75
Usually 14
Sometimes 11
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 13
Somewhat hard to take 29
A little hard to take 24
Not at all hard to take 38
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 7
$50-99 15
$25-49 5
< $25 33
Not specified 40

What people switch to and from

Patients started taking asenapine after stopping:

Treatment Patients
Quetiapine (Seroquel) 9
Lamotrigine (Lamictal) 5
Lithium Carbonate (Lithium Carbonate ER) 5
Aripiprazole (Abilify) 4
Fluoxetine (Prozac) 3

Show all 20 treatments patients report switching from

Patients stopped taking asenapine and switched to:

Treatment Patients
Risperidone (Risperdal) 2
Sertraline (Zoloft) 2
Brexpiprazole (Rexulti) 1
Divalproex sodium (Depakote) 1
Escitalopram (Lexapro) 1

Show all 12 treatments patients report switching to

Last updated:

6 patient evaluations for asenapine

73 members have decided to share their profiles only with other members of PatientsLikeMe.

CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 0
External Stress: Severe
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full asenapine history

May 24, 2016 (Started May 18, 2016)

  • Effectiveness
    Major (for Suicidal thoughts or urges)
  • Effectiveness
    Moderate (for Psychogenic Non-epileptic Seizures)
  • Effectiveness
    Moderate (for Irritability)
  • Effectiveness
    Slight (for Dissociation)
  • Effectiveness
    Moderate (for Anxious mood)
  • Effectiveness
    Moderate (for Anger)
  • Effectiveness
    Slight (for Depersonalization-derealization)
  • Effectiveness
    Slight (for Confusion)
  • Side effects
    Severe (Difficulty sleeping through night, Daytime sleepiness, Sedation)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
isilzha
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isilzha
Gender: F
Data Quality: 0 stars
Pain: Most
Fatigue: Some
Sleep: All
Stiffness: Some
function: None
external_stress: Most
Stickman: most
Description:F43y
FM:13y Dx
I am: n
I have:
Fibromyalgia

See isilzha's full asenapine history

Jun 22, 2012 (Started Mar 21, 2012)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    Mild (Excessive daytime sleepiness (somnolence))
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 10 mg Daily
Advice & Tips: Ugh, the cherry taste (it's a sublingual med) is horrendous, though I was told the original unflavored was even worse. Hard to imagine! =) That said, it actually helps me sleep better than the trazadone because it doesn't seem to cause the bizarre lucid dreams that trazadone gives me.
Cost: < $25 monthly

  • 0 helpful marks
rudicollis
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rudicollis
Gender: F
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 2
Compulsion: 2
External Stress: Moderate
28 F
Function: High
Distress: Low
I am: n
I have:
Schizophrenia

See rudicollis's full asenapine history

Feb 7, 2012 (Started Apr 15, 2010)

  • Effectiveness
    Major (for Schizophrenia)
  • Side effects
    Mild (Bad taste in mouth)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Cost: $50-99 monthly
Side effects: Bad taste in mouth

Jun 13, 2010 (Started Apr 15, 2010)

  • Effectiveness
    Major (for Schizophrenia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: Though the taste is horrible, this is honestly the best psychiatric medication I have ever taken. It has nearly eliminated all of my schizophrenic symptoms including visual and auditory hallucinations, paranoia, racing thoughts, and disorganized thoughts, speech and behavior - Just to name a few. I have never felt better since I've been on this, and it works quickly if you need an emergency dose - in about 10 minutes I can feel a difference. I highly suggest you try this medication. The side effects are nearly non-existent.
Cost: $50-99 monthly
Side effects: Bad taste in mouth

Apr 19, 2010 (Started Apr 15, 2010)

  • Effectiveness
    Moderate (for Schizophrenia)
  • Side effects
    Moderate (Bad taste in mouth)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly
Side effects: Bad taste in mouth

  • 1 helpful mark
Last updated:
Showing 3 of 6 patient evaluations for asenapine