What is Morphine Sulfate IR (MSIR)?

Category: Prescription Drugs

Most popular types: Statex


Generic name: Morphine

Morphine Sulfate is available in short acting preparations, known as Immediate Release (MSIR) formulations. It is effective rapidly, especially when taken in the liquid formulation. It is often referred to as "rescue" or "breakthrough" doses when used with long-acting preparations

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Pain 46 21
Fibromyalgia 26 7
Breakthrough pain 20 17
Pain in lower back 3 1
Osteoarthritis 2 1

Show all 29 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 4
Moderate 9
Mild 17
None 17

Commonly reported side effects and conditions associated with Morphine Sulfate IR (MSIR)

Side effect Patients
Constipation 9
Nausea 4
Decreased level of consciousness 3
Excessive daytime sleepiness (somnolence) 2
Fatigue 2
Headaches 2

Show all 28 reported side effects


Based on patients currently taking Morphine Sulfate IR (MSIR)

Dosage Patients
30mg as needed 3
15 mg daily 2
15 mg three times daily 2
60 mg daily 2
30 mg twice daily 1
30 mg four times daily 1
12,600 mg daily 1
0.5 15mg as needed 1
15mg as needed 1
4mg as needed 1

Why patients stopped taking Morphine Sulfate IR (MSIR)

Multiple reasons could be selected

Reason Patients
Doctor's advice 8
Other 7
Did not seem to work 5
Side effects too severe 5
Personal research 4
Change in health plan coverage 2
Course of treatment ended 2
See all 25 patients who've stopped taking Morphine Sulfate IR (MSIR)


Currently taking Morphine Sulfate IR (MSIR)

Duration Patients
1 - 6 months 1
6 months - 1 year 2
1 - 2 years 1
2 - 5 years 6
5 - 10 years 4
10 years or more 3

Stopped taking Morphine Sulfate IR (MSIR)

Duration Patients
Less than 1 month 5
1 - 6 months 7
6 months - 1 year 3
1 - 2 years 3
2 - 5 years 4
5 - 10 years 1
10 years or more 3
Adherence Evaluations
Always 29
Usually 11
Sometimes 3
Never taken as prescribed 4
Burden Evaluations
Very hard to take 1
Somewhat hard to take 10
A little hard to take 6
Not at all hard to take 30
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 3
$25-49 2
< $25 25
Not specified 17

What people switch to and from

Patients started taking Morphine Sulfate IR (MSIR) after stopping:

Treatment Patients
Hydromorphone (Dilaudid) 4
Oxycodone (Oxycodone IR) 4
Hydrocodone-Acetaminophen (Norco) 2
Oxycodone-acetaminophen (Percocet) 2
Buprenorphine patch (BuTrans patch) 1

Show all 8 treatments patients report switching from

Patients stopped taking Morphine Sulfate IR (MSIR) and switched to:

Treatment Patients
Hydromorphone (Dilaudid) 3
Hydrocodone-Acetaminophen (Norco) 2
Cannabis (Marijuana) 1
Levorphanol 1
Morphine (Morphine ER) 1

Show all 6 treatments patients report switching to

Last updated:

7 patient evaluations for Morphine Sulfate IR (MSIR)

Mar 18, 2018 (Started Jul 01, 2017)

  • Effectiveness
    None (for breakthrough pain)
  • Side effects
  • Adherence
  • Burden
    Somewhat hard to take
Dosage: 15 mg Daily
Advice & Tips: If you are still in a lot of pain after taking this, nor find one to be enough; perhaps bring it up to your doctor. Honestly, I need a larger dose, and more frequently. Unfortunately, most of the time, doctors aren't going to budge... Even if you have a legitimate need for it. People are allowed to suffer all too often. If my pain gets even worse, I rarely break down and take more. They don't understand a patient taking opiates develops a tolerance. (rendering the tiny dose less effective, or not effective at all).

  • 0 helpful marks

Jul 1, 2013 (Started Jul 01, 2013)

  • Effectiveness
    Major (for chronic pain)
  • Effectiveness
    Major (for breakthrough pain)
  • Side effects
    Mild (sleepiness)
  • Adherence
  • Burden
    A little hard to take
Dosage: 45 mg Daily
Advice & Tips: No problem with this medication, it worked great on breakthrough pain. My only concern was that I would develop a high tolerance for it and if I was ever seriously injured or became chronically ill, then it would not be affective. I also know now that I was not educated properly by my PCP at the time. I was given the false pretense that this medication would eliminate my pain 100%. After I struggled for over a year with managing my pain (and not taking medication properly because of being uneducated) I did the research on my conditions and pain medications and learned that you are always going to feel up to 30% of pain and the goal should be to lower the pain level as much as possible with medications and alternative methods like a heating pad for example.

  • 1 helpful mark

Nov 13, 2012 (Started Nov 11, 2011)

  • Effectiveness
    Major (for chronic pain)
  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
  • Adherence
  • Burden
    Not at all hard to take
Dosage: 45 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 7 patient evaluations for Morphine Sulfate IR (MSIR)