What is FOLFOX regimen?

Category: Prescription Drugs


The chemotherapy regimen Folfox includes folinic acid, Fluorouracil , and Oxaliplatin. Dosing guidelines for chemotherapy protocols will vary by stage of disease and are determined by an oncology specialist based on the individual needs of the patient.

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 1
Moderate 1
Mild 1
None 0

Commonly reported side effects and conditions associated with FOLFOX regimen

Side effect Patients
Nausea 3
Blurry vision 1
Chemo brain 1
Cold intolerance 1
Fatigue 1
Restless feeling in legs 1

Why patients stopped taking FOLFOX regimen

Multiple reasons could be selected

Reason Patients
Course of treatment ended 1
Did not seem to work 1
Doctor's advice 1
See all 3 patients who've stopped taking FOLFOX regimen


Currently taking FOLFOX regimen

Duration Patients
2 - 5 years 1

Stopped taking FOLFOX regimen

Duration Patients
1 - 6 months 2
6 months - 1 year 1
Adherence Evaluations
Always 2
Usually 1
Sometimes 0
Never taken as prescribed 0
Burden Evaluations
Very hard to take 1
Somewhat hard to take 0
A little hard to take 1
Not at all hard to take 1
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 0
$25-49 0
< $25 1
Not specified 2

What people switch to and from

Patients started taking FOLFOX regimen after stopping:

Treatment Patients
Chemotherapy 1

Patients stopped taking FOLFOX regimen and switched to:

Treatment Patients
FOLFIRI regimen 2
Irinotecan (Camptosar) 1
Last updated:

1 patient evaluation for FOLFOX regimen

Jul 14, 2010 (Started Nov 19, 2009)

  • Effectiveness
    Major (for colon cancer)
  • Side effects
  • Adherence
  • Burden
    Very hard to take
Dosage: Every Other Week
Advice & Tips: FOLFOX is 5-flourourocil (5-FU), leukovorin, and oxaliplatin. I got it by I/V over two hours and then wore a pump with 95ml of 5-FU for 48 hours, every two weeks. Oxaliplatin causes cold-induced acute peripheral neuropathy, along with other possible side-effects. It also has a dose-limiting toxicity resulting in long-term numbness/tingling in hands and feet. My doc stopped the oxaliplatin after treatment 10 of 12. Result has been poor balance (can't feel feet) and bad fine motor control (tying shoes, buttoning shirt).
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 1 of 1 patient evaluation for FOLFOX regimen