What is Sulfamethoxazole-Trimethoprim (cotrimoxazole)?

Category: Prescription Drugs

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Sulfamethoxazole-trimethoprim, also known as SMX-TMP or cotrimoxazole, is a combination of sulfamethoxazole, an antibacterial sulfonamide, and trimethoprim. The combination eliminates bacteria that cause many kinds of infections, including pneumonia and urinary tract and intestinal infections.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent infection 175 76
UTI (Urinary Tract Infection) 58 36
Sinus Infection (Sinusitis) 20 6
HIV (Human Immunodeficiency Virus) 16 4
General health 15 6
Infection 15 5

Show all 87 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 14
Moderate 10
Mild 39
None 131

Commonly reported side effects and conditions associated with Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Side effect Patients
Nausea 7
Diarrhea 5
Abdominal cramps 2
Alternating constipation and diarrhea 2
Itching 2
Rashes (redness, swelling) 2

Show all 57 reported side effects

Dosages

Based on patients currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Dosage Patients
400 mg-80 mg m,w,f 6
800-160 mg m,w,f 5
400-80 mg daily 5
400 mg-80 mg daily 3
800-160 mg twice daily 3
800 mg-160 mg m,w,f 2
400 mg-80 mg twice daily 2
800-160 mg daily 2
1 mg m,w,f 1
1 tablet(s) m,w,f 1

See all 24 dosages

Why patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Multiple reasons could be selected

Reason Patients
Course of treatment ended 142
Doctor's advice 57
Side effects too severe 26
Did not seem to work 11
Other 11
Personal research 1
See all 217 patients who’ve stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration

Currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients
1 - 6 months 10
6 months - 1 year 6
1 - 2 years 12
2 - 5 years 11
5 - 10 years 3
10 years or more 2

Stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients
Less than 1 month 102
1 - 6 months 49
6 months - 1 year 31
1 - 2 years 20
2 - 5 years 11
5 - 10 years 5
10 years or more 3
Adherence
Adherence Evaluations
Always 162
Usually 17
Sometimes 7
Never taken as prescribed 8
Burden
Burden Evaluations
Very hard to take 7
Somewhat hard to take 9
A little hard to take 26
Not at all hard to take 152
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 10
< $25 96
Not specified 87

What people switch to and from

Patients started taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) after stopping:

Treatment Patients
Clarithromycin (Biaxin) 2
Azithromycin (Zithromax) 1
Cephalexin (Keflex) 1
Ciprofloxacin (Cipro) 1
codeine-guaifenesin syrup (Cheratussin AC) 1

Show all 10 treatments patients report switching from

Patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) and switched to:

Treatment Patients
Artemether-lumefantrine 1
Cephalexin (Keflex) 1
Ciprofloxacin (Cipro) 1
Clindamycin (Clindamycin PH 1% Gel) 1
Dapsone (DDS) (Aczone) 1

Show all 10 treatments patients report switching to

Last updated:

25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)

165 members have decided to share their profiles only with other members of PatientsLikeMe.

desrat
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desrat
Sex: M
Data Quality: 3 stars
Relapse: Moderate
Sensation: None
Overall: Mild
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: none
Upper limb: mild
Walking: mild
I am: n
I have:
MS

See desrat's full Sulfamethoxazole-Trimethoprim (cotrimoxazole) history

Aug 23, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for Cysts)
  • Side effects
    Mild (Nausea, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Advice & Tips: Cyst is almost gone
Cost: < $25 monthly

Aug 19, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for Cysts)
  • Side effects
    Mild (Nausea, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Advice & Tips: My stomach feels upset from time to time on days when I take this. The cyst I'm taking this for has shrunk, could be gone in a week.
Cost: < $25 monthly

Aug 15, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for Cysts)
  • Side effects
    Mild (Nausea, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks
pheonix61
45106 thumb
pheonix61
Data Quality: 1 star
  • Gender: M
  • Age: 65
Condition: COPD 43 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: n
I have:
COPD

See pheonix61's full Sulfamethoxazole-Trimethoprim (cotrimoxazole) history

Jan 6, 2014 (Started Dec 13, 2013)

  • Effectiveness
    Moderate (for UTI (Urinary Tract Infection))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Cost: < $25 monthly

Dec 26, 2013 (Started Dec 13, 2013)

  • Effectiveness
    Moderate (for UTI (Urinary Tract Infection))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 2 x 200 mg-40 mg/5 mL Daily
Cost: < $25 monthly

  • 0 helpful marks
jpolden15
153 thumb
jpolden15
Sex: M
Data Quality: 2 stars
Bulbar: moderate
Arms: moderate
Chest: moderate
Legs: severe
I am: b
I have:
ALS

See jpolden15's full Sulfamethoxazole-Trimethoprim (cotrimoxazole) history

Dec 23, 2012 (Started Dec 22, 2012)

  • Effectiveness
    Moderate (for UTI (Urinary Tract Infection))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1200 mg Daily
Advice & Tips: good for clearing Urinary infection
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)