What is Sulfamethoxazole-Trimethoprim (cotrimoxazole)?

Category: Prescription Drugs

Most popular types: Bactrim Bactrim DS Septra Show all

false

Sulfamethoxazole-trimethoprim, also known as SMX-TMP or cotrimoxazole, is a combination of sulfamethoxazole, an antibacterial sulfonamide, and trimethoprim. The combination eliminates bacteria that cause many kinds of infections, including pneumonia and urinary tract and intestinal infections.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent infection 185 83
Urinary tract infection 68 43
Sinus infection (sinusitis) 23 7
Human immunodeficiency virus (HIV) 16 4
General health 15 6

Show all 65 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 16
Moderate 15
Mild 47
None 140

Commonly reported side effects and conditions associated with Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Side effect Patients
Nausea 7
Diarrhea 5
Abdominal cramps 2
Itching 2
Rashes (redness, swelling) 2
Skin sensitivity to sun (photosensitivity) 2

Show all 54 reported side effects

Dosages

Based on patients currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Dosage Patients
400-80 mg daily 5
800-160 mg daily 5
800-160 mg twice daily 4
400 mg-80 mg m,w,f 2
800-160 mg m,w,f 2
800 mg-160 mg m,w,f 2
800 mg-160 mg daily 2
1 tablet(s) m,w,f 1
1 mg daily 1
10 mg daily 1

See all 21 dosages

Why patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Multiple reasons could be selected

Reason Patients
Course of treatment ended 153
Doctor's advice 62
Side effects too severe 28
Did not seem to work 14
Other 12
Personal research 1
See all 235 patients who've stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration

Currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients
1 - 6 months 4
6 months - 1 year 4
1 - 2 years 9
2 - 5 years 13
5 - 10 years 6

Stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients
Less than 1 month 112
1 - 6 months 54
6 months - 1 year 33
1 - 2 years 22
2 - 5 years 12
5 - 10 years 5
10 years or more 3
Adherence
Adherence Evaluations
Always 184
Usually 18
Sometimes 7
Never taken as prescribed 9
Burden
Burden Evaluations
Very hard to take 7
Somewhat hard to take 9
A little hard to take 31
Not at all hard to take 171
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 10
< $25 115
Not specified 92

What people switch to and from

Patients started taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) after stopping:

Treatment Patients
Cephalexin (Keflex) 3
Clarithromycin (Biaxin) 2
Amoxicillin-clavulanate (Augmentin) 1
Azithromycin (Zithromax) 1
Ciprofloxacin (Cipro) 1

Show all 10 treatments patients report switching from

Patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) and switched to:

Treatment Patients
Amoxicillin (Amoxil) 1
Antibiotics 1
Artemether-lumefantrine 1
Atovaquone (Mepron) 1
Cephalexin (Keflex) 1

Show all 15 treatments patients report switching to

Last updated:

25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Nov 16, 2008 (Started Oct 04, 2008)

  • Effectiveness
    Moderate (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 800 mg-160 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Sep 4, 2008 (Started Aug 11, 2008)

  • Effectiveness
    Major (for Other)
  • Side effects
    Severe (sickness, weight loss, anxious mood)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 7680 mg Daily
Side effects: anxious mood, sickness, weight loss

  • 0 helpful marks

Dec 1, 1997 (Started )

  • Effectiveness
    None (for Support immune health)
  • Side effects
    Severe (fever, nausea)
  • Adherence
    Usually
  • Burden
    Very hard to take
Advice & Tips: Try the Bactrim desensitizing treatment to see if it might help in being able to take this usually-effective, inexpensive medicine. After twice failing desensitization, I was placed on Diflucan tablets when my t-cell count was below 200 count.
Side effects: nausea, fever

  • 0 helpful marks
Last updated:
Showing 3 of 25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)