You should not use this medication if you are allergic to bisoprolol, or if you have certain serious heart conditions such as"AV block” or slow heart rhythm.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take bisoprolol, tell your doctor if you have:
- asthma, bronchitis, emphysema;
- diabetes (taking bisoprolol can make it harder for you to tell when you have low blood sugar);
- a heart problem such as angina, heart block, slow heart rhythm, or congestive heart failure;
- liver or kidney disease;
- a thyroid disorder; or
- problems with circulation (such as Raynaud's syndrome).
FDA pregnancy category C. It is not known whether bisoprolol is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether bisoprolol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Bisoprolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid drinking alcohol. It can increase some of the side effects of bisoprolol.
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include slow heart rate, wheezing or shortness of breath, dizziness, anxiety, confusion, nausea, sweating, pale skin, fainting, and seizure (convulsions).
Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- slow, fast, or pounding heartbeats;
- chest pain, feeling like you might pass out;
- confusion, hallucinations;
- feeling short of breath, even with mild exertion;
- swelling of your ankles or feet;
- pain or burning when you urinate; or
- numbness, tingling, or cold feeling in your hands and feet.
Less serious side effects may include:
- dry mouth, nausea, vomiting, stomach pain;
- diarrhea, constipation, increased urination;
- runny or stuffy nose, ringing in your ears;
- feeling tired or weak;
- sleep problems (insomnia);
- drowsiness, dizziness, spinning sensation;
- depression, anxiety, restless feeling;
- joint or muscle pain;
- mild itching or skin rash; or
- loss of interest in sex.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you use, especially:
- clonidine (Catapres);
- digitalis (digoxin, Lanoxin);
- disopyramide (Norpace);
- guanethidine (Ismelin);
- rifampin (Rifadin, Rifater, Rifamate);
- insulin or diabetes medication you take by mouth;
- another beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;
- a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), or diltiazem (Cartia, Cardizem); or
- medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and others.
This list is not complete and there may be other drugs that can interact with bisoprolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Zebeta and bisoprolol
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Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04