Mycophenolic acid is an immunosuppressant agent, it is used to prevent organ rejection in allogeneic renal transplants. Off-label it is used for moderate–severe psoriasis; proliferative lupus nephritis; myasthenia gravis; prevention and treatment of graft-versus-host disease.
Perceived effectiveness for Transplant rejection prevention:
Perceived effectiveness for Kidney transplant rejection and organ removal:
Advice & Tips:
I am having extreme difficulty with this medication. In the middle of 2010, it attacked my uterus giving me so much bleeding and pain I had to have it removed. Doctors say that is not a side effect of this medication, I beg to differ. I still have much trouble with it causing extreme puking and Diarrhea always beginning with these rotten egg burps. My doctors say there is nothing else they can give me. I need to look into other doctors now.
No benefits for this medication for me.
It impacts my life badly.
Perceived effectiveness for Transplant rejection prevention:
Not at all
Advice & Tips:
I was switched to Myfortic because I was taking cellcelpt and a biopsy showed cellcept colitis, it was aweful. I was taking 1000mg of that twice a day. Now on the myfortic, my Nephrologist started me on a low dose and it turns out that my labs stayed great on that low dose, so now I take 1 tab of 180mg twice a day and I have less pills. I have had no problems with this drug.
< $25 monthly
Showing 3 of 5 patient evaluations for Mycophenolic acid
Mycophenolic acid lowers your body’s immune system. The immune system helps your body fight infections. The immune system can also fight or "reject” a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.
Mycophenolic acid is used to prevent your body from rejecting a kidney transplant. This medication is usually given with cyclosporine (Sandimmune, Neoral) and a steroid medication.
Mycophenolic acid may also be used for other purposes not listed in this medication guide.
You should not use this medication if you are allergic to mycophenolic acid or mycophenolate mofetil (CellCept).
Before using mycophenolic acid, tell your doctor if you are allergic to any drugs, or if you have:
a stomach ulcer or other disorders of your stomach or intestines;
a viral, bacterial, or fungal infection; or
a rare hereditary deficiency of hypoxanthine-guanine phosphoribosyl-transferase (HGPRT) such as Lesch-Nyhan and Kelley-Seegmiller syndrome.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.
FDA pregnancy category D. This medication can cause harm to an unborn baby, especially if used during the first trimester of pregnancy. Do not use mycophenolic acid without telling your doctor if you are pregnant or if you plan to become pregnant during treatment.
If you are a woman of child-bearing potential, you will be required to receive contraceptive counseling and to start using two forms of birth control 4 weeks before the start of your treatment with mycophenolic acid. You will also need to have a negative pregnancy test within 1 week before your treatment begins.
Unless you have been in menopause for at least 12 months in a row, you are considered to be of child-bearing potential. Adolescent girls who have entered puberty are also considered to be of child-bearing potential, even if not yet sexually active.
Use two non-hormone forms of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy before and during your treatment with mycophenolic acid, and for at least 6 weeks after your treatment ends. Tell your doctor right away if you become pregnant.
Mycophenolic acid can make birth control pills less effective. Ask your doctor about the most effective non-hormonal forms of birth control and which two are best for you.
Although mycophenolic acid can cause harm to an unborn baby, not treating the mother with this medication after a transplant could pose a greater risk to the mother’s health. Mycophenolic acid is sometimes given to pregnant women who are unable to take other needed transplant medications. Your doctor will decide whether you should receive this medication.
Your name may need to be listed on a national transplant pregnancy registry if you use mycophenolic acid during pregnancy. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether mycophenolic acid had any effect on the baby.
It is not known whether mycophenolic acid passes into breast milk or if it could harm a nursing baby. Do not breast-feed a baby while taking mycophenolic acid and for at least 6 weeks after your treatment ends.
Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.
Do not receive a "live” vaccine while you are being treated with mycophenolic acid. The live vaccine may not work as well during your treatment, and may not fully protect you from disease. You may still be able to receive a flu shot, but ask your doctor first.
Avoid taking an antacid together with mycophenolic acid. Antacids contain different medicines and some types can make it harder for your body to absorb mycophenolic acid.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Mycophenolic acid can increase your risk of skin cancer. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, diarrhea, stomach pain, unusual bleeding or bruising, and signs of infection.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Before using mycophenolic acid, tell your doctor if you are using any of the following drugs:
cholestyramine (Questran), colesevelam (Welchol), or colestipol (Colestid);
acyclovir (Zovirax) or ganciclovir (Cytovene); or
other medicines that weaken the immune system, such as azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), or mycophenolate mofetil (CellCept).
This list is not complete and there may be other drugs that can interact with mycophenolic acid. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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