What is succimer?

Succimer is a chelating (binding) agent. Succimer binds to lead in the blood and allows it to be passed out in the urine.

Succimer is used in the treatment of lead poisoning.

Succimer may also be used for purposes other than those listed here.


Before taking succimer, talk to your doctor if you have

  • had a previous reaction to treatment with succimer;
  • blood problems;
  • kidney problems; or
  • liver problems.

You may not be able to take succimer, or you may require a dosage adjustment or special monitoring during treatment.

Succimer is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take succimer without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether succimer passes into breast milk and if it will affect a nursing baby. Do not take succimer without first talking to your doctor if you are breast-feeding a baby.

Succimer can lower the activity of the immune system making you more susceptible to infection. Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection such as fever, sore throat, or coughing.

Use caution when driving, operating machinery, or performing other hazardous activities. Succimer may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.

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Seek emergency medical attention if an overdose is suspected.

Symptoms of a succimer overdose may include poor coordination, weakness, seizures, difficulty breathing, and death.

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose unless otherwise directed by your doctor.

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Side effects

Seek emergency medical attention or contact your doctor immediately if you experience any of the following rare but serious side effects to succimer:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • skin rash or sores in the mouth; or
  • signs of infection such as fever, sore throat, or coughing.

Other, less serious side effects may be more likely to occur. Continue to take succimer and talk to your doctor if you experience

  • nausea, vomiting, or decreased appetite;
  • diarrhea;
  • metallic taste in the mouth;
  • drowsiness;
  • dizziness;
  • watering eyes; or
  • headache.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

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No other medications are known to interact with succimer. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Other Names

Chemet and succimer

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Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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