What is Zonisamide?

Category: Prescription Drugs

Most popular types: Zonegran

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Zonisamide is an anticonvulsant drug that may be used in combination with other anti-seizure medications to treat partial seizures. 

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 310 168
Migraine headaches 47 23
Seizures (complex partial) 40 30
Nerve pain (neuralgia) 9 1
Seizures 8 2
Seizures (grand mal or tonic-clonic) 8 7

Show all 56 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 54
Moderate 53
Mild 44
None 61

Commonly reported side effects and conditions associated with Zonisamide

Side effect Patients
Decreased appetite 9
Drowsiness 7
Fatigue 7
Memory problems 7
Weight loss 7
Headaches 6

Show all 100 reported side effects

Dosages

Based on patients currently taking Zonisamide

Dosage Patients
400 mg daily 7
100 mg daily 6
50 mg daily 5
100 mg twice daily 4
200 mg daily 4
150 mg daily 3
300 mg daily 3
25 mg daily 2
200 mg twice daily 2
500 mg daily 2

See all 13 dosages

Why patients stopped taking Zonisamide

Multiple reasons could be selected

Reason Patients
Side effects too severe 55
Did not seem to work 49
Doctor's advice 41
Other 9
Expense 6
Course of treatment ended 4
Personal research 3
Change in health plan coverage 2
See all 121 patients who've stopped taking Zonisamide

Duration

Currently taking Zonisamide

Duration Patients
1 - 6 months 4
1 - 2 years 5
2 - 5 years 11
5 - 10 years 13
10 years or more 7

Stopped taking Zonisamide

Duration Patients
Less than 1 month 31
1 - 6 months 25
6 months - 1 year 17
1 - 2 years 19
2 - 5 years 18
5 - 10 years 10
10 years or more 1
Adherence
Adherence Evaluations
Always 174
Usually 24
Sometimes 4
Never taken as prescribed 10
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 14
A little hard to take 27
Not at all hard to take 157
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 4
$50-99 10
$25-49 16
< $25 83
Not specified 95

What people switch to and from

Patients started taking Zonisamide after stopping:

Treatment Patients
Topiramate (Topamax) 11
Lamotrigine (Lamictal) 6
Levetiracetam (Keppra) 4
Phenytoin (Dilantin) 4
Gabapentin (Neurontin) 3

Show all 13 treatments patients report switching from

Patients stopped taking Zonisamide and switched to:

Treatment Patients
Topiramate (Topamax) 3
Levetiracetam (Keppra) 2
Botulinum Toxin Type A (Botox) 1
Divalproex sodium (Depakote) 1
Duloxetine (Cymbalta) 1

Show all 10 treatments patients report switching to

Last updated:

17 patient evaluations for Zonisamide

Jan 3, 2017 (Started Oct 09, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Dec 16, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Can't tell (for epilepsy)
  • Side effects
    Severe (decreased appetite, depression with suicidal thoughts, mood swings, anger, numbness and tingling in hands, increased anxiety, suicidal thoughts or urges)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

Jun 30, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Can't tell (for epilepsy)
  • Side effects
    Severe (decreased appetite, depression with suicidal thoughts, mood swings, anger, numbness and tingling in hands, increased anxiety, suicidal thoughts or urges)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Sep 4, 2013 (Started Aug 02, 2013)

  • Effectiveness
    Can't tell (for migraine headaches)
  • Side effects
    Moderate (nightmares, suicidal, depressed mood, headaches)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 17 patient evaluations for Zonisamide