What is Topiramate?

Category: Prescription Drugs

Most popular types: Topamax Trokendi XR Topamax Sprinkle Show all

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Topiramate is an anti-convulsant and is used with other medications to treat certain types of seizures in patients with epilepsy or Lennox-Gastaut syndrome. It is also used to prevent migraine or cluster headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Migraine headaches 1,173 483
Epilepsy 726 401
Headaches 185 88
Fibromyalgia 121 78
Cluster headaches 102 54
Pain 74 32

Show all 241 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
258
Moderate
356
Mild
281
None
381

Commonly reported side effects and conditions associated with Topiramate

Side effect Patients
Weight loss 95
Memory problems 55
Brain fog 54
Hands tingling 53
Word fishing 52
Feet tingling 48

Show all 418 reported side effects

Dosages

Based on patients currently taking Topiramate

Dosage Patients
100 mg daily 61
100 mg twice daily 41
50 mg twice daily 37
200 mg daily 37
25 mg twice daily 33
50 mg daily 32
25 mg daily 26
200 mg twice daily 21
400 mg daily 20
150 mg daily 13

See all 41 dosages

Why patients stopped taking Topiramate

Multiple reasons could be selected

Reason Patients
Side effects too severe 396
Did not seem to work 263
Doctor's advice 218
Other 109
Expense 38
Personal research 34
Course of treatment ended 30
Change in health plan coverage 11
See all 757 patients who've stopped taking Topiramate

Duration

Currently taking Topiramate

Duration Patients
Less than 1 month 2
1 - 6 months 26
6 months - 1 year 26
1 - 2 years 46
2 - 5 years 100
5 - 10 years 112
10 years or more 82

Stopped taking Topiramate

Duration Patients
Less than 1 month 130
1 - 6 months 203
6 months - 1 year 114
1 - 2 years 104
2 - 5 years 134
5 - 10 years 59
10 years or more 18
Adherence
Adherence Evaluations
Always 1083
Usually 135
Sometimes 23
Never taken as prescribed 35
Burden
Burden Evaluations
Very hard to take 49
Somewhat hard to take 92
A little hard to take 181
Not at all hard to take 954
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 12
$50-99 35
$25-49 104
< $25 591
Not specified 515

What people switch to and from

Patients started taking Topiramate after stopping:

Treatment Patients
Sumatriptan (Imitrex) 13
Gabapentin (Neurontin) 12
Propranolol (Inderal) 11
Lamotrigine (Lamictal) 10
Divalproex sodium (Depakote) 8

Show all 49 treatments patients report switching from

Patients stopped taking Topiramate and switched to:

Treatment Patients
Gabapentin (Neurontin) 15
Divalproex sodium (Depakote) 12
Lamotrigine (Lamictal) 12
Amitriptyline (Elavil) 6
Botulinum Toxin Type A (Botox) 6

Show all 47 treatments patients report switching to

Last updated:

116 patient evaluations for Topiramate

Apr 8, 2009 (Started Mar 04, 2009)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    None (for nerve pain (neuralgia))
  • Effectiveness
    Slight (for migraine headaches)
  • Side effects
    Moderate (sleepiness, hands tingling, feet tingling, tremor in hands, nausea)
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 75 mg Daily
Advice & Tips: I will ask to quit this because for me it hasn't prevented the migraines enough....ended up at doctor's office yesterday for a shot for one.....and the side effects lost me a month of activity.
Cost: $25-49 monthly
Side effects: feet tingling, hands tingling, tremor in hands, nausea, brain fog, sleepiness

  • 4 helpful marks

Mar 1, 2010 (Started Jul 30, 2009)

  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Made me very tired and gave me diarrhea.
Cost: < $25 monthly

  • 2 helpful marks

Oct 27, 2010 (Started Jan 01, 2004)

  • Effectiveness
    Moderate (for epilepsy)
  • Side effects
    Severe (unexplained itching, hearing problems, blurry vision, weight loss)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Hearing loss is becoming more obvious, vision problems are rapidly becoming a problem also. itching of my larger skin areas is an unusual and new problem that could maybe be due to Topamax or the antidepressant Prozac, unsure about this. I have had terrible crying jags and depression over inappropriate issues in the last year or so that was assumed to be due to my aging process, but was recently debunked by a hormonal test. I therefore believe that the Topamax is a more likely suspect.
Cost: < $25 monthly
Side effects: weight loss, blurry vision, hearing problems, unexplained itching, unexplained itching

Feb 15, 2010 (Started Jan 01, 2004)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    Moderate (hearing problems, blurry vision, weight loss)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: The side effects of Topamax are really tough, but not as tough as others, and certainly not as tough as beating the heck out of yourself and frying your brain during a seizure. I never miss a dose, if I do, I could really end up hurting myself. I take it as exactly to the minute as I can, I do the same with all my meds, and for the last several years since I have been doing this, my seizures have been much less invasive into my life. I also NEVER NEVER take generic epilepsy medication. It must be brand always! Generic is NOT the same, no matter who insists that it is. I can take generic on other medication, but generic Topamax allowed me to have 3 months of severe cluster seizures last year.
Cost: < $25 monthly
Side effects: weight loss, blurry vision, hearing problems, unexplained itching, unexplained itching

  • 2 helpful marks
Last updated:
Showing 3 of 116 patient evaluations for Topiramate