What is Topiramate?

Category: Prescription Drugs

Most popular types: Topamax Trokendi XR Topamax Sprinkle Show all

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Topiramate is an anti-convulsant and is used with other medications to treat certain types of seizures in patients with epilepsy or Lennox-Gastaut syndrome. It is also used to prevent migraine or cluster headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Migraine headaches 1,223 514
Epilepsy 731 405
Headaches 185 89
Fibromyalgia 123 80
Cluster headaches 107 58
Pain 75 33

Show all 247 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 265
Moderate 369
Mild 296
None 402

Commonly reported side effects and conditions associated with Topiramate

Side effect Patients
Weight loss 98
Decreased appetite 59
Memory problems 57
Hands tingling 56
Brain fog 55
Word fishing 53

Show all 420 reported side effects

Dosages

Based on patients currently taking Topiramate

Dosage Patients
100 mg daily 58
100 mg twice daily 48
50 mg twice daily 39
50 mg daily 32
25 mg twice daily 29
25 mg daily 23
200 mg daily 22
200 mg twice daily 22
150 mg daily 16
400 mg daily 15

See all 42 dosages

Why patients stopped taking Topiramate

Multiple reasons could be selected

Reason Patients
Side effects too severe 413
Did not seem to work 270
Doctor's advice 227
Other 109
Expense 39
Personal research 35
Course of treatment ended 31
Change in health plan coverage 12
See all 781 patients who've stopped taking Topiramate

Duration

Currently taking Topiramate

Duration Patients
Less than 1 month 2
1 - 6 months 15
6 months - 1 year 37
1 - 2 years 50
2 - 5 years 116
5 - 10 years 97
10 years or more 63

Stopped taking Topiramate

Duration Patients
Less than 1 month 141
1 - 6 months 207
6 months - 1 year 113
1 - 2 years 105
2 - 5 years 141
5 - 10 years 62
10 years or more 18
Adherence
Adherence Evaluations
Always 1129
Usually 141
Sometimes 23
Never taken as prescribed 39
Burden
Burden Evaluations
Very hard to take 48
Somewhat hard to take 97
A little hard to take 186
Not at all hard to take 1001
Cost per month
Cost per month Evaluations
$200+ 20
$100-199 12
$50-99 35
$25-49 105
< $25 611
Not specified 549

What people switch to and from

Patients started taking Topiramate after stopping:

Treatment Patients
Gabapentin (Neurontin) 16
Sumatriptan (Imitrex) 13
Lamotrigine (Lamictal) 11
Propranolol (Inderal) 10
Divalproex sodium (Depakote) 8

Show all 51 treatments patients report switching from

Patients stopped taking Topiramate and switched to:

Treatment Patients
Gabapentin (Neurontin) 16
Divalproex sodium (Depakote) 15
Lamotrigine (Lamictal) 13
Botulinum Toxin Type A (Botox) 7
Zonisamide (Zonegran) 7

Show all 50 treatments patients report switching to

Last updated:

117 patient evaluations for Topiramate

Aug 15, 2004 (Started Jul 01, 2004)

  • Effectiveness
    None (for nerve pain (neuralgia))
  • Side effects
    Severe (headaches, mood swings, nausea, head tingling)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: Be very careful with this medication and take as directed. Make sure to follow directions if you need to stop this medication due to serious side effects and withdrawls including seizures.
Cost: $25-49 monthly
Side effects: head tingling, nausea, mood swings, headaches

  • 0 helpful marks

Apr 1, 2002 (Started Apr 01, 2002)

  • Effectiveness
    Moderate (for epilepsy)
  • Side effects
    Severe (acidosis)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Side effects: acidosis

  • 0 helpful marks

Jul 7, 2000 (Started May 28, 2000)

  • Effectiveness
    Slight (for BOTH EPILEPY AND PHYSCOSIS)
  • Effectiveness
    Slight (for epilepsy)
  • Side effects
    Severe (ACUTE PHYSCOSIS WICH HAD TO BE TREATED WITH PROMAZINE 50 MG ORAL OR IM, psychotic symptoms (anxiety depression fear))
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 200 mg Daily
Advice & Tips: The impact this drug had on my social and my whole life were unpleasant, it was given me both to treat my epilepsy and physocis I was going through at the time. The only alternative was Carbamazipine which was ruled out due to severe liver damage. I was on a mental health unit at this time and was treated with it whilst in hospital
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 117 patient evaluations for Topiramate