What is Olanzapine?

Category: Prescription Drugs

Most popular types: Zyprexa Zyprexa Zydis Novo-Olanzapine Show all

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See also: Symbyax

Olanzapine is a member of a class of medications known as atypical antipsychotics. It works by changing the activity of certain natural substances in the brain. It may be used to treat the symptoms of schizophrenia, bipolar disorder, or depression.  

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 250 141
Schizoaffective disorder 41 29
Psychosis disorder 35 26
Schizophrenia 28 24
Anxious mood 25 20
Bipolar I disorder 20 19

Show all 99 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 104
Moderate 73
Mild 45
None 49

Commonly reported side effects and conditions associated with Olanzapine

Side effect Patients
Weight gain 85
Lethargy 17
Sedation 15
Rapid weight gain 14
Fatigue 13
Sleepiness 9

Show all 112 reported side effects

Dosages

Based on patients currently taking Olanzapine

Dosage Patients
5 mg daily 18
10 mg daily 14
2.5 mg daily 10
20 mg daily 6
7.5 mg daily 3
15 mg daily 3
2.5 mg twice daily 1
6 mg daily 1
5 mg three times daily 1
10 mg twice daily 1

See all 16 dosages

Why patients stopped taking Olanzapine

Multiple reasons could be selected

Reason Patients
Side effects too severe 187
Doctor's advice 95
Did not seem to work 77
Other 27
Course of treatment ended 26
Personal research 20
Expense 11
Change in health plan coverage 6
See all 303 patients who've stopped taking Olanzapine

Duration

Currently taking Olanzapine

Duration Patients
1 - 6 months 10
6 months - 1 year 11
1 - 2 years 13
2 - 5 years 11
5 - 10 years 10
10 years or more 9

Stopped taking Olanzapine

Duration Patients
Less than 1 month 93
1 - 6 months 81
6 months - 1 year 48
1 - 2 years 33
2 - 5 years 33
5 - 10 years 11
10 years or more 7
Adherence
Adherence Evaluations
Always 212
Usually 29
Sometimes 14
Never taken as prescribed 16
Burden
Burden Evaluations
Very hard to take 26
Somewhat hard to take 34
A little hard to take 33
Not at all hard to take 178
Cost per month
Cost per month Evaluations
$200+ 11
$100-199 4
$50-99 5
$25-49 6
< $25 102
Not specified 143

What people switch to and from

Patients started taking Olanzapine after stopping:

Treatment Patients
Aripiprazole (Abilify) 8
Quetiapine (Seroquel) 8
Risperidone (Risperdal) 8
Fluoxetine (Prozac) 5
Lithium Carbonate (Lithium Carbonate ER) 5

Show all 32 treatments patients report switching from

Patients stopped taking Olanzapine and switched to:

Treatment Patients
Quetiapine (Seroquel) 12
Lurasidone (Latuda) 11
Lamotrigine (Lamictal) 10
Aripiprazole (Abilify) 7
Divalproex sodium (Depakote) 4

Show all 21 treatments patients report switching to

Last updated:

24 patient evaluations for Olanzapine

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Slight (for schizophrenia)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for Mania)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 20 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Major (for Mania)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg All the time (24/7)

  • 1 helpful mark

May 1, 2017 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for paranoid schizophrenia)
  • Effectiveness
    Major (for Auditory hallucinations)
  • Side effects
    Mild (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: I have been on Zyprexa for over four years and I no longer feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and being very delusional. But, before Zyprexa I did believe in these things (powers) were true for me, but now I do not. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, after starting Zyprexa on Dec 13, 2012, I no longer believe this is/was probably ever true. Zyprexa, work better with less side effects., than those in 1977 when I started taking antipsychotic medications. I may have gotten the side effect of an internal restlessness that makes you want to move, akathista, from those earlier antipsychotic medications and not from Zyprexa.
Cost: < $25 monthly

Dec 16, 2016 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for paranoid schizophrenia)
  • Effectiveness
    Major (for Auditory hallucinations)
  • Side effects
    Moderate (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Advice & Tips: I have been on Zyprexa for about four years and I no longer feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and being very delusional. But, before Zyprexa I did believe in these things (powers) were true for me, but now I do not. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, after starting Zyprexa on Dec 13, 2012, I no longer believe this is/was probably ever true. Zyprexa, work better with less side effects., than those in 1977 when I started taking antipsychotic medications. I may have gotten the side effect of an internal restlessness that makes you want to move, akathista, from those earlier antipsychotic medications and not from Zyprexa.
Cost: < $25 monthly

Sep 25, 2015 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for paranoid schizophrenia)
  • Side effects
    Mild (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I have been on Zyprexa for about two and half years and I no longer feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and being very delusional. But, before Zyprexa I did believe in these things (powers) were true for me, but now I do not. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, after starting Zyprexa on Dec 13, 2012, I no longer believe this is/was ever true. Zyprexa, work better with less side effects., than those in 1977 when I started taking antipsychotic medications. I may have gotten the side effect of an internal restlessness that makes you want to move, akathista, from those earlier antipsychotic medications and not from Zyprexa.
Cost: < $25 monthly

Feb 24, 2015 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Effectiveness
    Major (for paranoid schizophrenia)
  • Side effects
    Severe (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I did not believe this medication would change anything for me, but it did. It works even though I did not believe it would. I use to feel my psychotic symptoms were truly real, but after being on Zyprexa for awhile, I now believe they are not and never were truly real. The side effect of internal restlessness (akathisia) is bad.
Cost: < $25 monthly

Jun 12, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Side effects
    Severe (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Apr 13, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Side effects
    Severe (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Mar 17, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Side effects
    Severe (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Feb 25, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Side effects
    Severe (Restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Apr 29, 2013 (Started Dec 13, 2012)

  • Effectiveness
    Major (for schizoaffective disorder)
  • Effectiveness
    Major (for psychosis disorder)
  • Effectiveness
    Major (for schizophrenia)
  • Effectiveness
    Can’t tell (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily

  • 1 helpful mark

Dec 12, 2016 (Started Jul 01, 2015)

  • Effectiveness
    Major (for recover)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I know that every persons seizures are different, but Olanzapine has helped my recovery time after a grand mal seizure. As soon as I wake and realize I've had a seizure I take one, then I take another one the following morning if needed. I didn't call in to work at all last year because of a seizure.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 24 patient evaluations for Olanzapine