What is Olanzapine?

Category: Prescription Drugs

Most popular types: Zyprexa Zyprexa Zydis Novo-Olanzapine Show all

false

See also: Symbyax

Olanzapine is a member of a class of medications known as atypical antipsychotics. It works by changing the activity of certain natural substances in the brain. It may be used to treat the symptoms of schizophrenia, bipolar disorder, or depression.  

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 202 106
Psychosis Disorder 33 23
Schizoaffective Disorder 33 20
Anxious mood 25 17
Schizophrenia 24 19
Bipolar I Disorder 18 17

Show all 100 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 83
Moderate 59
Mild 38
None 35

Commonly reported side effects and conditions associated with Olanzapine

Side effect Patients
Weight gain 63
Lethargy 15
Sedation 15
Rapid weight gain 13
Fatigue 9
Sleepiness 9

Show all 95 reported side effects

Dosages

Based on patients currently taking Olanzapine

Dosage Patients
20 mg daily 10
5 mg daily 8
10 mg daily 1
2.5 mg daily 6
15 mg daily 4
15 mg twice daily 2
5mg as needed 2
4 mg daily 1
20 mg twice daily 1

Why patients stopped taking Olanzapine

Multiple reasons could be selected

Reason Patients
Side effects too severe 165
Doctor's advice 83
Did not seem to work 65
Course of treatment ended 26
Other 24
Personal research 19
Expense 9
Change in health plan coverage 4
See all 263 patients who’ve stopped taking Olanzapine

Duration

Currently taking Olanzapine

Duration Patients
Less than 1 month 1
1 - 6 months 5
6 months - 1 year 8
1 - 2 years 8
2 - 5 years 8
5 - 10 years 6
10 years or more 7

Stopped taking Olanzapine

Duration Patients
Less than 1 month 81
1 - 6 months 69
6 months - 1 year 45
1 - 2 years 30
2 - 5 years 26
5 - 10 years 11
10 years or more 4
Adherence
Adherence Evaluations
Always 174
Usually 23
Sometimes 9
Never taken as prescribed 9
Burden
Burden Evaluations
Very hard to take 22
Somewhat hard to take 27
A little hard to take 27
Not at all hard to take 139
Cost per month
Cost per month Evaluations
$200+ 11
$100-199 4
$50-99 4
$25-49 5
< $25 81
Not specified 110

What people switch to and from

Patients started taking Olanzapine after stopping:

Treatment Patients
Risperidone (Risperdal) 7
Aripiprazole (Abilify) 3
Lithium Carbonate (Lithium Carbonate ER) 3
Quetiapine (Seroquel) 3
Ziprasidone (Geodon) 3

Show all 23 treatments patients report switching from

Patients stopped taking Olanzapine and switched to:

Treatment Patients
Quetiapine (Seroquel) 11
Lurasidone (Latuda) 8
Aripiprazole (Abilify) 6
Lamotrigine (Lamictal) 4
Risperidone (Risperdal) 4

Show all 16 treatments patients report switching to

Last updated:

23 patient evaluations for Olanzapine

155 members have decided to share their profiles only with other members of PatientsLikeMe.

God's Worshipper
11071 thumb
God's Worshipper
Gender: M
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Low
59 M
Function: High
Distress: Low
I am: b
I have:
Schizoaffective Disorder

See God's Worshipper's full Olanzapine history

Sep 25, 2015 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Paranoid Schizophrenia)
  • Side effects
    Mild (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I have been on Zyprexa for about two and half years and I no longer feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and being very delusional. But, before Zyprexa I did believe in these things (powers) were true for me, but now I do not. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, after starting Zyprexa on Dec 13, 2012, I no longer believe this is/was ever true. Zyprexa, work better with less side effects., than those in 1977 when I started taking antipsychotic medications. I may have gotten the side effect of an internal restlessness that makes you want to move, akathista, from those earlier antipsychotic medications and not from Zyprexa.
Cost: < $25 monthly

Feb 24, 2015 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Major (for Paranoid Schizophrenia)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I did not believe this medication would change anything for me, but it did. It works even though I did not believe it would. I use to feel my psychotic symptoms were truly real, but after being on Zyprexa for awhile, I now believe they are not and never were truly real. The side effect of internal restlessness (akathisia) is bad.
Cost: < $25 monthly

Jun 12, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Apr 13, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Mar 17, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Feb 25, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Apr 29, 2013 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily

  • 1 helpful mark
JedRy01
74118 thumb
JedRy01
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 2
Emotional: 3
Anxiety: 3
Compulsion: 2
External Stress: None
44 M
Function: Low
Distress: Moderate
I am: vb
I have:
Bipolar I

See JedRy01's full Olanzapine history

Dec 23, 2014 (Started Dec 15, 2014)

  • Effectiveness
    None (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 2.5 mg Daily
Advice & Tips: I have been told by others that this can change my personality, so I am getting my medication reviewed

  • 0 helpful marks
TheTrishgu
Portrait default thumb
TheTrishgu
Gender: F
Data Quality: 1 star
Depression: 2
Mania: 0
Emotional: 1
Anxiety: 2
Compulsion: 2
External Stress: Severe
35 F
Function: Moderate
Distress: Moderate
I am: b
I have:
Bipolar Disorder

See TheTrishgu's full Olanzapine history

Jun 15, 2013 (Started Jun 01, 2011)

  • Effectiveness
    Slight (for Bipolar Disorder)
  • Side effects
    Severe (Fatigue)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Apr 22, 2012 (Started Jun 01, 2011)

  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Side effects
    Mild (Fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 23 patient evaluations for Olanzapine