What is Olanzapine?

Category: Prescription Drugs

Most popular types: Zyprexa Zyprexa Zydis Novo-Olanzapine Show all

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See also: Symbyax

Olanzapine is a member of a class of medications known as atypical antipsychotics. It works by changing the activity of certain natural substances in the brain. It may be used to treat the symptoms of schizophrenia, bipolar disorder, or depression.  

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 210 115
Psychosis Disorder 34 24
Schizoaffective Disorder 34 22
Anxious mood 25 17
Schizophrenia 25 20
Bipolar I Disorder 18 17

Show all 100 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 89
Moderate 61
Mild 39
None 37

Commonly reported side effects and conditions associated with Olanzapine

Side effect Patients
Weight gain 68
Lethargy 16
Sedation 15
Rapid weight gain 13
Fatigue 9
Sleepiness 9

Show all 97 reported side effects

Dosages

Based on patients currently taking Olanzapine

Dosage Patients
20 mg daily 13
10 mg daily 1
5 mg daily 7
2.5 mg daily 5
15 mg daily 3
5mg as needed 3
15 mg twice daily 2
3.6 mg daily 1
20 mg twice daily 1

Why patients stopped taking Olanzapine

Multiple reasons could be selected

Reason Patients
Side effects too severe 170
Doctor's advice 83
Did not seem to work 65
Course of treatment ended 26
Other 24
Personal research 19
Expense 9
Change in health plan coverage 4
See all 267 patients who’ve stopped taking Olanzapine

Duration

Currently taking Olanzapine

Duration Patients
Less than 1 month 1
1 - 6 months 4
6 months - 1 year 8
1 - 2 years 10
2 - 5 years 9
5 - 10 years 6
10 years or more 10

Stopped taking Olanzapine

Duration Patients
Less than 1 month 84
1 - 6 months 71
6 months - 1 year 45
1 - 2 years 29
2 - 5 years 26
5 - 10 years 11
10 years or more 4
Adherence
Adherence Evaluations
Always 180
Usually 26
Sometimes 10
Never taken as prescribed 10
Burden
Burden Evaluations
Very hard to take 25
Somewhat hard to take 28
A little hard to take 28
Not at all hard to take 145
Cost per month
Cost per month Evaluations
$200+ 11
$100-199 4
$50-99 4
$25-49 6
< $25 84
Not specified 117

What people switch to and from

Patients started taking Olanzapine after stopping:

Treatment Patients
Risperidone (Risperdal) 6
Aripiprazole (Abilify) 5
Divalproex sodium (Depakote) 3
Lithium Carbonate (Lithium Carbonate ER) 3
Quetiapine (Seroquel) 3

Show all 23 treatments patients report switching from

Patients stopped taking Olanzapine and switched to:

Treatment Patients
Quetiapine (Seroquel) 10
Lurasidone (Latuda) 9
Aripiprazole (Abilify) 6
Lamotrigine (Lamictal) 4
Risperidone (Risperdal) 4

Show all 16 treatments patients report switching to

Last updated:

24 patient evaluations for Olanzapine

164 members have decided to share their profiles only with other members of PatientsLikeMe.

God's Worshipper
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God's Worshipper
Gender: M
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Low
59 M
Function: High
Distress: Low
I am: n
I have:
Schizoaffective Disorder

See God's Worshipper's full Olanzapine history

Dec 16, 2016 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Paranoid Schizophrenia)
  • Effectiveness
    Major (for Auditory hallucinations)
  • Side effects
    Moderate (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I have been on Zyprexa for about four years and I no longer feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and being very delusional. But, before Zyprexa I did believe in these things (powers) were true for me, but now I do not. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, after starting Zyprexa on Dec 13, 2012, I no longer believe this is/was probably ever true. Zyprexa, work better with less side effects., than those in 1977 when I started taking antipsychotic medications. I may have gotten the side effect of an internal restlessness that makes you want to move, akathista, from those earlier antipsychotic medications and not from Zyprexa.
Cost: < $25 monthly

Sep 25, 2015 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Paranoid Schizophrenia)
  • Side effects
    Mild (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I have been on Zyprexa for about two and half years and I no longer feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and being very delusional. But, before Zyprexa I did believe in these things (powers) were true for me, but now I do not. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, after starting Zyprexa on Dec 13, 2012, I no longer believe this is/was ever true. Zyprexa, work better with less side effects., than those in 1977 when I started taking antipsychotic medications. I may have gotten the side effect of an internal restlessness that makes you want to move, akathista, from those earlier antipsychotic medications and not from Zyprexa.
Cost: < $25 monthly

Feb 24, 2015 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Major (for Paranoid Schizophrenia)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I did not believe this medication would change anything for me, but it did. It works even though I did not believe it would. I use to feel my psychotic symptoms were truly real, but after being on Zyprexa for awhile, I now believe they are not and never were truly real. The side effect of internal restlessness (akathisia) is bad.
Cost: < $25 monthly

Jun 12, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Apr 13, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Mar 17, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Feb 25, 2014 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    Severe (Internal restlessness (akathisia), Stiffness in legs, Restless feeling in legs, Sex drive (libido) decreased)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily
Cost: < $25 monthly

Apr 29, 2013 (Started Dec 13, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Psychosis Disorder)
  • Effectiveness
    Major (for Schizophrenia)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 15 mg Daily

  • 1 helpful mark
joan53
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joan53
Data Quality: 2 stars
  • Gender: F
  • Age: 53y
  • Duration: 52 yrs
PRO survey: PRO 3
Quality of life:
  • Mental: None
  • Physical: None
0 seizures
4 weeks ago
I am: vg
I have:
Epilepsy

See joan53's full Olanzapine history

Dec 12, 2016 (Started Jul 01, 2015)

  • Effectiveness
    Major (for recover)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I know that every persons seizures are different, but Olanzapine has helped my recovery time after a grand mal seizure. As soon as I wake and realize I've had a seizure I take one, then I take another one the following morning if needed. I didn't call in to work at all last year because of a seizure.
Cost: < $25 monthly

  • 0 helpful marks
JedRy01
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JedRy01
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 2
Emotional: 3
Anxiety: 3
Compulsion: 2
External Stress: None
44 M
Function: Low
Distress: Moderate
I am: vb
I have:
Bipolar I

See JedRy01's full Olanzapine history

Dec 23, 2014 (Started Dec 15, 2014)

  • Effectiveness
    None (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 2.5 mg Daily
Advice & Tips: I have been told by others that this can change my personality, so I am getting my medication reviewed

  • 0 helpful marks
Last updated:
Showing 3 of 24 patient evaluations for Olanzapine