What is Doxepin?

Category: Prescription Drugs

Most popular types: Sinequan Silenor Deptran Show all

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Doxepin is a tricyclic antidepressant used to treat depression. Off label it is used as an analgesic for certain chronic and neuropathic pain and for anxiety.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Sleep problems 90 54
Insomnia 71 49
Depressed mood 17 6
Fibromyalgia 14 4
Pain 10 5
Tension Headache 7 1

Show all 62 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 16
Moderate 18
Mild 21
None 55

Commonly reported side effects and conditions associated with Doxepin

Side effect Patients
Groggy in morning 5
Drowsiness 4
Daytime sleepiness 3
Dry mouth 3
Excessive daytime sleepiness (somnolence) 3
Excessive dry mouth 3

Show all 47 reported side effects

Dosages

Based on patients currently taking Doxepin

Dosage Patients
25 mg daily 6
50 mg daily 6
10 mg daily 4
100 mg daily 3
150 mg daily 2
200 mg daily 2
1 mmol/L daily 1
6 mg daily 1
20 mg daily 1
20 mg twice daily 1

See all 16 dosages

Why patients stopped taking Doxepin

Multiple reasons could be selected

Reason Patients
Did not seem to work 33
Side effects too severe 26
Doctor's advice 20
Other 16
Course of treatment ended 6
Change in health plan coverage 1
Personal research 1
See all 80 patients who’ve stopped taking Doxepin

Duration

Currently taking Doxepin

Duration Patients
1 - 6 months 3
6 months - 1 year 3
1 - 2 years 10
2 - 5 years 8
5 - 10 years 4
10 years or more 4

Stopped taking Doxepin

Duration Patients
Less than 1 month 19
1 - 6 months 25
6 months - 1 year 14
1 - 2 years 8
2 - 5 years 9
5 - 10 years 2
10 years or more 3
Adherence
Adherence Evaluations
Always 86
Usually 17
Sometimes 4
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 7
A little hard to take 17
Not at all hard to take 81
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 8
< $25 67
Not specified 34

What people switch to and from

Patients started taking Doxepin after stopping:

Treatment Patients
Trazodone (Desyrel) 7
Zolpidem (Ambien) 6
Quetiapine (Seroquel) 2
Alprazolam (Xanax) 1
Amitriptyline (Elavil) 1

Show all 15 treatments patients report switching from

Patients stopped taking Doxepin and switched to:

Treatment Patients
Trazodone (Desyrel) 3
Amitriptyline (Elavil) 1
asenapine (Saphris) 1
Bupropion (Wellbutrin XL) 1
Clonidine (Catapres TTS patch) 1

Show all 11 treatments patients report switching to

Last updated:

10 patient evaluations for Doxepin

82 members have decided to share their profiles only with other members of PatientsLikeMe.

Ronnell0053
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Ronnell0053
Gender: M
Data Quality: 3 stars
Mental Symptoms : none
Physical Symptoms : none
791
VL 38
I am: vg
I have:
HIV

See Ronnell0053's full Doxepin history

Jul 14, 2016 (Started Nov 15, 2013)

  • Effectiveness
    Major (for Sleep problems)
  • Effectiveness
    Major (for Depression with anxiety)
  • Side effects
    Mild (Excessive dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: The unexpected positive effect is causing drowsiness, which allows me to sleep at least eight full hours without worrying about the burden of insomnia, this has been a positive side effect since the Nov. 2013 month and year since I began taking Doxepin.
Cost: < $25 monthly

  • 0 helpful marks
Les1952
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Les1952
Sex: M
Data Quality: 2 stars
Sensation: None
Overall: Mild
Cognition: mild
Vision: moderate
Speech: mild
Swallowing: none
Upper limb: moderate
Walking: mild
I am: vg
I have:
MS

See Les1952's full Doxepin history

Dec 30, 2015 (Started May 15, 2015)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Effectiveness
    Slight (for Insomnia)
  • Side effects
    Moderate (Panic attacks)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: Originally I started to take it for insomnia and depression. I was constantly waking due to panic attacks so Doctor put me back on Resterol.
Cost: < $25 monthly

  • 0 helpful marks
KAB62
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KAB62
Gender: F
Data Quality: 1 star
Pain: Some
Fatigue: Most
Sleep: All
Stiffness: Most
function: Some
external_stress: Most
Stickman: most
Description:F54y
FM:14y Dx
I am: b
I have:
Fibromyalgia

See KAB62's full Doxepin history

Sep 22, 2013 (Started Jan 01, 2012)

  • Effectiveness
    Slight (for Insomnia)
  • Effectiveness
    Slight (for Sleep problems)
  • Side effects
    Moderate (Groggy in morning)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: Take 8-10 hours prior to the time you want to wake. Morning drowsiness.
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 10 patient evaluations for Doxepin