What is Doxepin?

Category: Prescription Drugs

Most popular types: Sinequan Silenor Prudoxin Show all

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Doxepin is a tricyclic antidepressant used to treat depression. It can also be applied on the skin to relieve itching associated with atopic dermatitis or lichen simplex chronicus. It may also be used as an analgesic for certain chronic and neuropathic pain and for anxiety.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 93 67
Depressed mood 16 5
Fibromyalgia 15 7
Pain 12 7
Tension headache 11 7

Show all 57 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 20
Moderate 23
Mild 29
None 77

Commonly reported side effects and conditions associated with Doxepin

Side effect Patients
Drowsiness 7
Dry mouth 5
Grogginess in morning 5
Weight gain 5
Dizziness 3
Excessive daytime sleepiness (somnolence) 3

Show all 49 reported side effects

Dosages

Based on patients currently taking Doxepin

Dosage Patients
10 mg daily 10
50 mg daily 10
25 mg daily 8
75 mg daily 4
150 mg daily 3
10mg as needed 3
3 mg daily 2
2.5 mg daily 1
6 mg daily 1
10 mg twice daily 1

See all 17 dosages

Why patients stopped taking Doxepin

Multiple reasons could be selected

Reason Patients
Did not seem to work 39
Doctor's advice 28
Side effects too severe 27
Other 17
Course of treatment ended 7
Change in health plan coverage 2
Expense 2
Personal research 2
See all 96 patients who've stopped taking Doxepin

Duration

Currently taking Doxepin

Duration Patients
Less than 1 month 1
1 - 6 months 3
6 months - 1 year 5
1 - 2 years 8
2 - 5 years 14
5 - 10 years 10
10 years or more 8

Stopped taking Doxepin

Duration Patients
Less than 1 month 23
1 - 6 months 28
6 months - 1 year 15
1 - 2 years 11
2 - 5 years 12
5 - 10 years 4
10 years or more 3
Adherence
Adherence Evaluations
Always 118
Usually 23
Sometimes 5
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 10
A little hard to take 21
Not at all hard to take 113
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 10
< $25 92
Not specified 46

What people switch to and from

Patients started taking Doxepin after stopping:

Treatment Patients
Trazodone (Desyrel) 11
Zolpidem (Ambien) 9
Temazepam (Restoril) 3
Alprazolam (Xanax) 2
Amitriptyline (Elavil) 2

Show all 21 treatments patients report switching from

Patients stopped taking Doxepin and switched to:

Treatment Patients
Trazodone (Desyrel) 7
Amitriptyline (Elavil) 2
Zolpidem (Ambien) 2
asenapine (Saphris) 1
Bupropion (Wellbutrin XL) 1

Show all 16 treatments patients report switching to

Last updated:

9 patient evaluations for Doxepin

Dec 30, 2015 (Started May 15, 2015)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Slight (for insomnia)
  • Side effects
    Moderate (panic attacks)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: Originally I started to take it for insomnia and depression. I was constantly waking due to panic attacks so Doctor put me back on Resterol.
Cost: < $25 monthly

  • 0 helpful marks

Sep 22, 2013 (Started Jan 01, 2012)

  • Effectiveness
    Slight (for insomnia)
  • Effectiveness
    Slight (for sleep problems)
  • Side effects
    Moderate (grogginess in morning)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: Take 8-10 hours prior to the time you want to wake. Morning drowsiness.
Cost: $25-49 monthly

  • 0 helpful marks

Sep 11, 2012 (Started Sep 25, 2010)

  • Effectiveness
    Can't tell (for irritable bowel syndrome)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 9 patient evaluations for Doxepin