What is Amitriptyline?

Category: Prescription Drugs

Most popular types: Elavil Endep Trepiline Show all

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Amitriptyline is a tricyclic antidepressant used for the treatment of depression. It may also be used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 1,018 655
Fibromyalgia 944 555
Pain 886 563
Depressed mood 196 116
Migraine headaches 160 105
Sleep problems 152 84

Show all 320 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 264
Moderate 389
Mild 512
None 646

Commonly reported side effects and conditions associated with Amitriptyline

Side effect Patients
Dry mouth 173
Weight gain 103
Drowsiness 76
Sleepiness 57
Excessive daytime sleepiness (somnolence) 50
Grogginess 45

Show all 319 reported side effects

Dosages

Based on patients currently taking Amitriptyline

Dosage Patients
25 mg daily 99
50 mg daily 82
10 mg daily 78
20 mg daily 35
75 mg daily 31
100 mg daily 30
30 mg daily 25
150 mg daily 9
10 mg twice daily 6
40 mg daily 6

See all 47 dosages

Why patients stopped taking Amitriptyline

Multiple reasons could be selected

Reason Patients
Did not seem to work 459
Side effects too severe 449
Doctor's advice 247
Other 165
Course of treatment ended 55
Personal research 52
Expense 15
Change in health plan coverage 11
See all 1073 patients who’ve stopped taking Amitriptyline

Duration

Currently taking Amitriptyline

Duration Patients
Less than 1 month 4
1 - 6 months 42
6 months - 1 year 46
1 - 2 years 63
2 - 5 years 134
5 - 10 years 96
10 years or more 72

Stopped taking Amitriptyline

Duration Patients
Less than 1 month 190
1 - 6 months 298
6 months - 1 year 176
1 - 2 years 144
2 - 5 years 174
5 - 10 years 59
10 years or more 37
Adherence
Adherence Evaluations
Always 1448
Usually 221
Sometimes 71
Never taken as prescribed 71
Burden
Burden Evaluations
Very hard to take 80
Somewhat hard to take 114
A little hard to take 232
Not at all hard to take 1385
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 3
$50-99 10
$25-49 40
< $25 932
Not specified 819

What people switch to and from

Patients started taking Amitriptyline after stopping:

Treatment Patients
Gabapentin (Neurontin) 13
Duloxetine (Cymbalta) 11
Trazodone (Desyrel) 8
Pregabalin (Lyrica) 7
Zolpidem (Ambien) 7

Show all 57 treatments patients report switching from

Patients stopped taking Amitriptyline and switched to:

Treatment Patients
Nortriptyline (Pamelor) 22
Gabapentin (Neurontin) 20
Pregabalin (Lyrica) 13
Duloxetine (Cymbalta) 11
Trazodone (Desyrel) 9

Show all 50 treatments patients report switching to

Last updated:

153 patient evaluations for Amitriptyline

1,305 members have decided to share their profiles only with other members of PatientsLikeMe.

steack2
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steack2
Gender: M
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 2
Anxiety: 2
Compulsion: 1
External Stress: Severe
44 M
Function: Moderate
Distress: Moderate
I am: vb
I have:
GAD

See steack2's full Amitriptyline history

May 19, 2017 (Started May 05, 2017)

  • Effectiveness
    Slight (for Neuropathy in hands)
  • Effectiveness
    Moderate (for Neuropathy in feet)
  • Side effects
    Moderate (Drunk feeling, Migraine headaches, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 drop(s) Daily

  • 0 helpful marks
donhing
154 thumb
donhing
Sex: M
Data Quality: 2 stars
Bulbar: severe
Arms: severe
Chest: severe
Legs: severe
I am: g
I have:
ALS

See donhing's full Amitriptyline history

Jan 20, 2017 (Started Nov 01, 2007)

  • Effectiveness
    Major (for Excess saliva)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
Ronnell0053
63555 thumb
Ronnell0053
Gender: M
Data Quality: 3 stars
Mental Symptoms : none
Physical Symptoms : none
983
VL 38
I am: vg
I have:
HIV

See Ronnell0053's full Amitriptyline history

Jan 11, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As an Ischemic Stroke survivor and current update &/or physically evaluated patient as required by my HIV Doctor during my every 90 days scheduled appointment, the benefit of Amitriptyline whether expected or not is the overall elimination of the numbness and tingling I use to experience prior to having been prescribed this drug, of which I'd give serious suggestive use of this drug to anyone experiencing numbness and/or tingling in their extremities, whether it's related to HIV or any other medical condition thus causing such an uncomfortable, concern warranting issue.
Cost: < $25 monthly

Jul 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As with all medicinal treatments, in order to achieve the best results, follow directions as prescribed and allow the medicine up to two weeks before being effective.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 153 patient evaluations for Amitriptyline