What is Amitriptyline?

Category: Prescription Drugs

Most popular types: Elavil Endep Trepiline Show all

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Amitriptyline is a tricyclic antidepressant approved for the treatment of depression. Off label amitripyline is used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 1,000 630
Fibromyalgia 925 534
Pain 871 542
Depressed mood 195 112
Migraine headaches 157 100
Sleep problems 152 83

Show all 313 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 252
Moderate 370
Mild 490
None 612

Commonly reported side effects and conditions associated with Amitriptyline

Side effect Patients
Dry mouth 165
Weight gain 102
Drowsiness 72
Sleepiness 54
Excessive daytime sleepiness (somnolence) 46
Grogginess 45

Show all 311 reported side effects

Dosages

Based on patients currently taking Amitriptyline

Dosage Patients
25 mg daily 94
50 mg daily 78
10 mg daily 70
100 mg daily 31
20 mg daily 30
75 mg daily 28
30 mg daily 15
150 mg daily 10
10 mg twice daily 5
40 mg daily 5

See all 33 dosages

Why patients stopped taking Amitriptyline

Multiple reasons could be selected

Reason Patients
Did not seem to work 450
Side effects too severe 438
Doctor's advice 241
Other 159
Course of treatment ended 52
Personal research 50
Expense 14
Change in health plan coverage 9
See all 1045 patients who’ve stopped taking Amitriptyline

Duration

Currently taking Amitriptyline

Duration Patients
Less than 1 month 5
1 - 6 months 31
6 months - 1 year 36
1 - 2 years 50
2 - 5 years 125
5 - 10 years 83
10 years or more 73

Stopped taking Amitriptyline

Duration Patients
Less than 1 month 186
1 - 6 months 292
6 months - 1 year 172
1 - 2 years 141
2 - 5 years 167
5 - 10 years 58
10 years or more 35
Adherence
Adherence Evaluations
Always 1377
Usually 215
Sometimes 68
Never taken as prescribed 64
Burden
Burden Evaluations
Very hard to take 78
Somewhat hard to take 111
A little hard to take 223
Not at all hard to take 1312
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 3
$50-99 8
$25-49 37
< $25 888
Not specified 781

What people switch to and from

Patients started taking Amitriptyline after stopping:

Treatment Patients
Gabapentin (Neurontin) 13
Duloxetine (Cymbalta) 8
Trazodone (Desyrel) 7
Pregabalin (Lyrica) 5
Topiramate (Topamax) 5

Show all 51 treatments patients report switching from

Patients stopped taking Amitriptyline and switched to:

Treatment Patients
Nortriptyline (Pamelor) 20
Gabapentin (Neurontin) 18
Pregabalin (Lyrica) 13
Duloxetine (Cymbalta) 9
Trazodone (Desyrel) 7

Show all 47 treatments patients report switching to

Last updated:

154 patient evaluations for Amitriptyline

1,244 members have decided to share their profiles only with other members of PatientsLikeMe.

donhing
154 thumb
donhing
Sex: M
Data Quality: 3 stars
Bulbar: severe
Arms: severe
Chest: severe
Legs: severe
I am: g
I have:
ALS

See donhing's full Amitriptyline history

Jan 20, 2017 (Started Nov 01, 2007)

  • Effectiveness
    Major (for Excess saliva)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
Ronnell0053
63555 thumb
Ronnell0053
Gender: M
Data Quality: 3 stars
Mental Symptoms : none
Physical Symptoms : none
985
VL 38
I am: vg
I have:
HIV

See Ronnell0053's full Amitriptyline history

Jan 11, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As an Ischemic Stroke survivor and current update &/or physically evaluated patient as required by my HIV Doctor during my every 90 days scheduled appointment, the benefit of Amitriptyline whether expected or not is the overall elimination of the numbness and tingling I use to experience prior to having been prescribed this drug, of which I'd give serious suggestive use of this drug to anyone experiencing numbness and/or tingling in their extremities, whether it's related to HIV or any other medical condition thus causing such an uncomfortable, concern warranting issue.
Cost: < $25 monthly

Jul 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As with all medicinal treatments, in order to achieve the best results, follow directions as prescribed and allow the medicine up to two weeks before being effective.
Cost: < $25 monthly

  • 0 helpful marks
sheronemus
8881 thumb
sheronemus
Sex: M
Data Quality: 2 stars
Bulbar: moderate
Arms: severe
Chest: moderate
Legs: moderate
I am: vg
I have:
ALS

See sheronemus's full Amitriptyline history

Oct 10, 2016 (Started Jul 01, 2009)

  • Effectiveness
    Moderate (for Excess saliva)
  • Side effects
    Mild (Drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 154 patient evaluations for Amitriptyline