What is Amitriptyline?

Category: Prescription Drugs

Most popular types: Elavil Endep Trepiline Show all

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Amitriptyline is a tricyclic antidepressant approved for the treatment of depression. Off label amitripyline is used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 971 607
Fibromyalgia 916 524
Pain 864 536
Depressed mood 195 111
Sleep problems 152 83
Migraine headaches 151 98

Show all 306 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 249
Moderate 366
Mild 469
None 595

Commonly reported side effects and conditions associated with Amitriptyline

Side effect Patients
Dry mouth 159
Weight gain 98
Drowsiness 69
Sleepiness 52
Excessive daytime sleepiness (somnolence) 46
Grogginess 44

Show all 304 reported side effects

Dosages

Based on patients currently taking Amitriptyline

Dosage Patients
25 mg daily 78
50 mg daily 70
10 mg daily 53
20 mg daily 31
100 mg daily 31
75 mg daily 24
30 mg daily 15
150 mg daily 10
10 mg twice daily 5
40 mg daily 4

See all 29 dosages

Why patients stopped taking Amitriptyline

Multiple reasons could be selected

Reason Patients
Did not seem to work 444
Side effects too severe 435
Doctor's advice 240
Other 159
Course of treatment ended 52
Personal research 50
Expense 14
Change in health plan coverage 8
See all 1036 patients who’ve stopped taking Amitriptyline

Duration

Currently taking Amitriptyline

Duration Patients
Less than 1 month 2
1 - 6 months 18
6 months - 1 year 26
1 - 2 years 47
2 - 5 years 115
5 - 10 years 75
10 years or more 69

Stopped taking Amitriptyline

Duration Patients
Less than 1 month 183
1 - 6 months 291
6 months - 1 year 172
1 - 2 years 140
2 - 5 years 163
5 - 10 years 58
10 years or more 35
Adherence
Adherence Evaluations
Always 1338
Usually 211
Sometimes 67
Never taken as prescribed 63
Burden
Burden Evaluations
Very hard to take 77
Somewhat hard to take 110
A little hard to take 218
Not at all hard to take 1274
Cost per month
Cost per month Evaluations
$200+ 6
$100-199 3
$50-99 8
$25-49 36
< $25 862
Not specified 764

What people switch to and from

Patients started taking Amitriptyline after stopping:

Treatment Patients
Gabapentin (Neurontin) 12
Duloxetine (Cymbalta) 8
Trazodone (Desyrel) 6
Pregabalin (Lyrica) 5
Topiramate (Topamax) 5

Show all 46 treatments patients report switching from

Patients stopped taking Amitriptyline and switched to:

Treatment Patients
Nortriptyline (Pamelor) 20
Gabapentin (Neurontin) 18
Pregabalin (Lyrica) 13
Duloxetine (Cymbalta) 9
Topiramate (Topamax) 6

Show all 47 treatments patients report switching to

Last updated:

153 patient evaluations for Amitriptyline

1,206 members have decided to share their profiles only with other members of PatientsLikeMe.

Ronnell0053
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Ronnell0053
Gender: M
Data Quality: 3 stars
Mental Symptoms : none
Physical Symptoms : none
791
VL 38
I am: vg
I have:
HIV

See Ronnell0053's full Amitriptyline history

Jan 11, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As an Ischemic Stroke survivor and current update &/or physically evaluated patient as required by my HIV Doctor during my every 90 days scheduled appointment, the benefit of Amitriptyline whether expected or not is the overall elimination of the numbness and tingling I use to experience prior to having been prescribed this drug, of which I'd give serious suggestive use of this drug to anyone experiencing numbness and/or tingling in their extremities, whether it's related to HIV or any other medical condition thus causing such an uncomfortable, concern warranting issue.
Cost: < $25 monthly

Jul 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As with all medicinal treatments, in order to achieve the best results, follow directions as prescribed and allow the medicine up to two weeks before being effective.
Cost: < $25 monthly

  • 0 helpful marks
sheronemus
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sheronemus
Sex: M
Data Quality: 2 stars
Bulbar: moderate
Arms: severe
Chest: moderate
Legs: moderate
I am: vg
I have:
ALS

See sheronemus's full Amitriptyline history

Oct 10, 2016 (Started Jul 01, 2009)

  • Effectiveness
    Moderate (for Excess saliva)
  • Side effects
    Mild (Drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
jasminefaery
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jasminefaery
Gender: F
Data Quality: 2 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 0
External Stress: Severe
55 F
Function: Moderate
Distress: Low
I am: g
I have:
Major Depressive Disorder

See jasminefaery's full Amitriptyline history

Aug 2, 2016 (Started Apr 19, 2012)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    Mild (Weight gain, Fluid retention weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Elavil is becoming unfamiliar with psychiatrists these days; they seem to feel that the old tricylics don't work as well as all the SSRI's that are out there now. Personally, over the vast amount of years with my psychiatrist, we tried everything from A-Z......always came back to Elavil. The SSRI's had terrible side effects & did not work as well. I think it's been quite effective! The weight gain used to be bad until I was dxed w/ Type 2 Diabetes (not on medication/just diet & exercise & glucose monitoring daily) Now I've been losing weight.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 153 patient evaluations for Amitriptyline