What is Amitriptyline?

Category: Prescription Drugs

Most popular types: Elavil Endep Trepiline Show all

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Amitriptyline is a tricyclic antidepressant used for the treatment of depression. It may also be used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 1,034 674
Fibromyalgia 960 575
Pain 899 574
Depressed mood 203 120
Migraine headaches 164 107
Sleep problems 153 84

Show all 329 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 271
Moderate 394
Mild 520
None 666

Commonly reported side effects and conditions associated with Amitriptyline

Side effect Patients
Dry mouth 177
Weight gain 106
Drowsiness 78
Sleepiness 57
Excessive daytime sleepiness (somnolence) 50
Grogginess 46

Show all 327 reported side effects

Dosages

Based on patients currently taking Amitriptyline

Dosage Patients
25 mg daily 99
10 mg daily 70
50 mg daily 67
20 mg daily 30
100 mg daily 30
75 mg daily 26
30 mg daily 24
150 mg daily 7
200 mg daily 7
10 mg twice daily 6

See all 48 dosages

Why patients stopped taking Amitriptyline

Multiple reasons could be selected

Reason Patients
Did not seem to work 468
Side effects too severe 458
Doctor's advice 249
Other 169
Course of treatment ended 57
Personal research 53
Expense 15
Change in health plan coverage 11
See all 1089 patients who've stopped taking Amitriptyline

Duration

Currently taking Amitriptyline

Duration Patients
1 - 6 months 23
6 months - 1 year 39
1 - 2 years 63
2 - 5 years 120
5 - 10 years 99
10 years or more 74

Stopped taking Amitriptyline

Duration Patients
Less than 1 month 193
1 - 6 months 304
6 months - 1 year 178
1 - 2 years 146
2 - 5 years 175
5 - 10 years 60
10 years or more 38
Adherence
Adherence Evaluations
Always 1481
Usually 222
Sometimes 72
Never taken as prescribed 76
Burden
Burden Evaluations
Very hard to take 84
Somewhat hard to take 118
A little hard to take 235
Not at all hard to take 1414
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 3
$50-99 10
$25-49 40
< $25 958
Not specified 833

What people switch to and from

Patients started taking Amitriptyline after stopping:

Treatment Patients
Gabapentin (Neurontin) 14
Duloxetine (Cymbalta) 13
Trazodone (Desyrel) 9
Zolpidem (Ambien) 8
Pregabalin (Lyrica) 7

Show all 63 treatments patients report switching from

Patients stopped taking Amitriptyline and switched to:

Treatment Patients
Nortriptyline (Pamelor) 24
Gabapentin (Neurontin) 21
Pregabalin (Lyrica) 14
Duloxetine (Cymbalta) 13
Trazodone (Desyrel) 9

Show all 53 treatments patients report switching to

Last updated:

154 patient evaluations for Amitriptyline

Jul 22, 2017 (Started Jul 01, 2002)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for Pain)
  • Effectiveness
    Moderate (for Insomnia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Cost: < $25 monthly

Dec 31, 2011 (Started Jul 01, 2002)

  • Effectiveness
    Slight (for Insomnia)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for Pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: This definitely helps with the problems I have sleeping, getting to sleep, staying asleep, getting restorative sleep, depression, and pain. I can tell more when I miss 2 or more nights, usually caused by a refill problem. I try to never run out and have to go without a dose. Missing doses causes all my problems like with sleeping, pain, and depression to become worse and my other medications don't seem as effective. I really take a nose dive if more than 2 doses are missed. Missing only 1 is tolerable, missing anymore becomes a big problem. I get anxious, teary, sleepless, and I feel hopeless. It is a horrible feeling.
Cost: < $25 monthly

  • 0 helpful marks

Jul 2, 2017 (Started Jan 15, 2016)

  • Effectiveness
    Slight (for peripheral neuropathy)
  • Side effects
    Moderate (Mood swings, Drowsiness)
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 50 mg Daily
Advice & Tips: The best way to take is at night otherwise i have found that day to day function can be very difficult
Cost: < $25 monthly

  • 0 helpful marks

May 19, 2017 (Started May 05, 2017)

  • Effectiveness
    Slight (for Neuropathy in hands)
  • Effectiveness
    Moderate (for Neuropathy in feet)
  • Side effects
    Moderate (Drunk feeling, Migraine headaches, Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 drop(s) Daily

  • 0 helpful marks
Last updated:
Showing 3 of 154 patient evaluations for Amitriptyline