What is Estradiol topical?

Category: Prescription Drugs

Most popular types: Estrace Vaginal Cream Vagifem Estring Show all

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See also: Wiley protocol HRT

Estradiol topical is a vaginal cream preparation used for the treatment of vulvar and vaginal atrophy; postmenopausal symptoms of urinary urgency and painful urination.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Vaginal dryness 13 5
Bladder problems 9 11
Support hormone balance 5 2
Vaginal atrophy 3 9
Vaginal pain 3 2

Show all 26 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 2
Moderate 2
Mild 1
None 25

Commonly reported side effects and conditions associated with Estradiol topical

Side effect Patients
Atopic dermatitis 1
Dry eyes 1
Pain in left eye 1
Rashes (redness, swelling) 1
Swelling in legs, feet and ankles 1
Urinary urgency 1

Show all 7 reported side effects

Dosages

Based on patients currently taking Estradiol topical

Dosage Patients
0.01 % m,w,f 3
0.01 % weekly 1
0.31 mcg every 3 months 1
0.01 % every other day 1
0.1 mg weekly 1
0.2 % weekly 1
0.1 mg m,w,f 1
0.1 % daily 1
0.25 % daily 1
0.25 % twice daily 1

See all 19 dosages

Why patients stopped taking Estradiol topical

Multiple reasons could be selected

Reason Patients
Other 5
Doctor's advice 4
Course of treatment ended 2
Side effects too severe 2
Did not seem to work 1
Expense 1
Personal research 1
See all 12 patients who've stopped taking Estradiol topical

Duration

Currently taking Estradiol topical

Duration Patients
6 months - 1 year 1
1 - 2 years 6
2 - 5 years 6
5 - 10 years 8
10 years or more 1

Stopped taking Estradiol topical

Duration Patients
Less than 1 month 3
1 - 6 months 3
6 months - 1 year 2
1 - 2 years 2
2 - 5 years 2
Adherence
Adherence Evaluations
Always 20
Usually 6
Sometimes 4
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 12
Somewhat hard to take 2
A little hard to take 7
Not at all hard to take 9
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 8
$50-99 2
$25-49 3
< $25 5
Not specified 11

What people switch to and from

Patients started taking Estradiol topical after stopping:

Treatment Patients
Estradiol Patch (Estrogen patch) 2
Estradiol (Estrace) 1
Levofloxacin (Levaquin) 1

Patients stopped taking Estradiol topical and switched to:

Treatment Patients
Pregabalin (Lyrica) 1
Last updated:

5 patient evaluations for Estradiol topical

Feb 16, 2011 (Started Sep 07, 2007)

  • Effectiveness
    Major (for bladder problems)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily

  • 0 helpful marks

Nov 15, 2010 (Started Jun 01, 2010)

  • Effectiveness
    Slight (for raise estrogen levels)
  • Side effects
    Moderate (dry eyes)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mcg Weekly
Advice & Tips: More urination, still dry and irritation....
Side effects: dry eyes

  • 0 helpful marks

Jun 25, 2010 (Started Jan 19, 2008)

  • Effectiveness
    Major (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg Weekly
Advice & Tips: According to my Urologist, I look good, and it seems to be doing it's job just fine!

Jan 19, 2009 (Started Jan 19, 2008)

  • Effectiveness
    Major (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg Weekly
Advice & Tips: Definitely use this instead of the cream version!

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Estradiol topical