What is Tacrolimus?

Category: Prescription Drugs

Most popular types: Prograf Advagraf Envarsus XR

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Tacrolimus (FK506) is an immunosuppressant agent. Taken orally or by injection it is used to prevent organ rejection in heart, kidney, or liver transplant recipients. Used as a topical skin product it is used for moderate-to-severe atopic dermatitis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent organ rejection 593 113
Transplant rejection prevention 378 101
Kidney Transplant 59 25
Transplant rejection 24 9
Kidney Transplant 22 7
Lung Transplant 14 3

Show all 28 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 16
Moderate 47
Mild 65
None 48

Commonly reported side effects and conditions associated with Tacrolimus

Side effect Patients
Tremor in hands 25
Hair loss 20
Fatigue 11
Hair thinning 10
Shakiness 8
Shaky hands 8

Show all 120 reported side effects

Dosages

Based on patients currently taking Tacrolimus

Dosage Patients
1 mg twice daily 7
3 mg daily 6
1 mg daily 3
2 mg daily 3
1.5 mg twice daily 3
2 mg twice daily 3
2.5 mg daily 2
4 mg daily 2
5 mg daily 2
3 mg twice daily 2

See all 21 dosages

Why patients stopped taking Tacrolimus

Multiple reasons could be selected

Reason Patients
Side effects too severe 22
Doctor's advice 15
Other 9
Course of treatment ended 7
Did not seem to work 6
Change in health plan coverage 2
Expense 2
Personal research 1
See all 49 patients who’ve stopped taking Tacrolimus

Duration

Currently taking Tacrolimus

Duration Patients
1 - 6 months 4
6 months - 1 year 2
1 - 2 years 1
2 - 5 years 10
5 - 10 years 17
10 years or more 11

Stopped taking Tacrolimus

Duration Patients
Less than 1 month 5
1 - 6 months 10
6 months - 1 year 10
1 - 2 years 6
2 - 5 years 11
5 - 10 years 6
10 years or more 1
Adherence
Adherence Evaluations
Always 163
Usually 9
Sometimes 2
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 7
A little hard to take 22
Not at all hard to take 142
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 9
$50-99 9
$25-49 8
< $25 76
Not specified 67

What people switch to and from

Patients started taking Tacrolimus after stopping:

Treatment Patients
Mycophenolate mofetil (CellCept) 3
Cyclosporine (Neoral) 2
Azathioprine (Imuran) 1

Patients stopped taking Tacrolimus and switched to:

Treatment Patients
Mycophenolate mofetil (CellCept) 2
Sirolimus (Rapamune) 2
Cyclosporine (Neoral) 1
Last updated:

27 patient evaluations for Tacrolimus

152 members have decided to share their profiles only with other members of PatientsLikeMe.

agoodwin
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agoodwin
Data Quality: 1 star
  • Sex: F
  • Age: 29y
  • Organ: Liver
Quality of life:
  • Mental: Mild
  • Physical: Mild
  1. Liver : 6y Transplanted
I have:
Liver Transplant

See agoodwin's full Tacrolimus history

Jul 9, 2015 (Started Sep 01, 2010)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Mild (Fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 mg Twice daily

  • 0 helpful marks
Chopped Liver
Portrait default thumb
Chopped Liver
Data Quality: 0 stars
  • Gender: F
  • Age: 54
Condition: Liver Cirrhosis 2 additional condition(s)
Quality of life:
  • Mental: Moderate
  • Physical: None
I am: vg
I have:
Liver Cirrhosis

See Chopped Liver's full Tacrolimus history

Feb 6, 2012 (Started Dec 01, 2009)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Moderate (Flu virus (influenza))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks
Karoger
38412 thumb
Karoger
Data Quality: 1 star
  • Sex: F
  • Age: 30y
  • Organ: Heart
Quality of life:
  • Mental: None
  • Physical: None
  1. Heart : 7y Transplanted
I have:
Heart Transplant

See Karoger's full Tacrolimus history

Nov 1, 2011 (Started Dec 16, 2010)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Moderate (Hair thinning, Hair loss, Tremor in hands)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3.5 mg/kg/day Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 27 patient evaluations for Tacrolimus