What is Tacrolimus?

Category: Prescription Drugs

Most popular types: Prograf Advagraf Envarsus XR

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Tacrolimus (FK506) is an immunosuppressant agent. Taken orally or by injection it is used to prevent organ rejection in heart, kidney, or liver transplant recipients. Used as a topical skin product it is used for moderate-to-severe atopic dermatitis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent organ rejection 593 116
Kidney transplant 59 26
Lung transplant 14 3
Liver transplant 9 6
Heart transplant 8 3

Show all 21 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
17
Moderate
48
Mild
69
None
47

Commonly reported side effects and conditions associated with Tacrolimus

Side effect Patients
Tremor in hands 26
Hair loss 20
Fatigue 11
Hair thinning 9
Shaky hands 9
Shakiness 8

Show all 121 reported side effects

Dosages

Based on patients currently taking Tacrolimus

Dosage Patients
1 mg twice daily 7
2 mg twice daily 7
4 mg daily 6
3 mg twice daily 6
5 mg daily 4
0.5 mg daily 3
1 mg daily 3
2 mg daily 2
1.5 mg twice daily 2
3 mg daily 2

See all 22 dosages

Why patients stopped taking Tacrolimus

Multiple reasons could be selected

Reason Patients
Side effects too severe 21
Doctor's advice 15
Other 9
Course of treatment ended 7
Did not seem to work 6
Change in health plan coverage 2
Expense 2
Personal research 1
See all 48 patients who've stopped taking Tacrolimus

Duration

Currently taking Tacrolimus

Duration Patients
1 - 6 months 3
6 months - 1 year 2
1 - 2 years 4
2 - 5 years 11
5 - 10 years 20
10 years or more 15

Stopped taking Tacrolimus

Duration Patients
Less than 1 month 5
1 - 6 months 11
6 months - 1 year 8
1 - 2 years 6
2 - 5 years 11
5 - 10 years 6
10 years or more 1
Adherence
Adherence Evaluations
Always 168
Usually 9
Sometimes 2
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 7
A little hard to take 22
Not at all hard to take 147
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 9
$50-99 9
$25-49 8
< $25 77
Not specified 71

What people switch to and from

Patients started taking Tacrolimus after stopping:

Treatment Patients
Mycophenolate mofetil (CellCept) 3
Azathioprine (Imuran) 1
Cyclosporine (Neoral) 1

Patients stopped taking Tacrolimus and switched to:

Treatment Patients
Mycophenolate mofetil (CellCept) 2
Sirolimus (Rapamune) 2
Last updated:

27 patient evaluations for Tacrolimus

Jul 9, 2015 (Started Sep 01, 2010)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 mg Twice daily

  • 0 helpful marks

Feb 6, 2012 (Started Dec 01, 2009)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Moderate (flu virus (influenza))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Nov 1, 2011 (Started Dec 16, 2010)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Side effects
    Moderate (hair thinning, hair loss, tremor in hands)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3.5 mg/kg/day Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 27 patient evaluations for Tacrolimus