What is Propoxyphene-Acetaminophen?

Category: Prescription Drugs

Most popular types: Darvocet-N 100 Darvocet-N 50 Darvocet A500 Show all

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See also: Dextropropoxyphene/paracetamol

This is an opioid analgesic combination of propoxyphene and acetaminophen used for mild to moderate pain. In 2010 the FDA sought market withdrawal of propoxyphene and requested manufacturers voluntarily remove their products after new clinical data showed potential for serious heart risks.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Pain 242 91
Fibromyalgia 29 22
Breakthrough pain 18 13
Pain in hips 13 9
Back pain 11 9
Headaches 10 5

Show all 38 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 3
Moderate 13
Mild 46
None 84

Commonly reported side effects and conditions associated with Propoxyphene-Acetaminophen

Side effect Patients
Constipation 10
Drowsiness 6
Sleepiness 6
Abdominal cramps 5
Drug tolerance 5
Dizziness 4

Show all 29 reported side effects

Dosages

Based on patients currently taking Propoxyphene-Acetaminophen

Dosage Patients
napsylate 325 mg-100 mg daily 1
napsylate650mg-100mg as needed 1

Why patients stopped taking Propoxyphene-Acetaminophen

Multiple reasons could be selected

Reason Patients
Other 66
Did not seem to work 44
Doctor's advice 36
Course of treatment ended 23
Side effects too severe 11
Personal research 4
Expense 1
See all 163 patients who’ve stopped taking Propoxyphene-Acetaminophen

Duration

Currently taking Propoxyphene-Acetaminophen

Duration Patients
5 - 10 years 1
10 years or more 1

Stopped taking Propoxyphene-Acetaminophen

Duration Patients
Less than 1 month 23
1 - 6 months 35
6 months - 1 year 20
1 - 2 years 24
2 - 5 years 31
5 - 10 years 16
10 years or more 14
Adherence
Adherence Evaluations
Always 76
Usually 40
Sometimes 25
Never taken as prescribed 5
Burden
Burden Evaluations
Very hard to take 4
Somewhat hard to take 7
A little hard to take 24
Not at all hard to take 111
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 1
$25-49 11
< $25 94
Not specified 39

What people switch to and from

Patients started taking Propoxyphene-Acetaminophen after stopping:

Treatment Patients
Hydrocodone-Acetaminophen (Norco) 1
Ibuprofen Prescription (Motrin Prescription) 1
Pregabalin (Lyrica) 1

Patients stopped taking Propoxyphene-Acetaminophen and switched to:

Treatment Patients
Oxycodone-acetaminophen (Percocet) 3
Tramadol (Ultram) 3
Codeine-acetaminophen (paracetamol) (Tylenol with Codeine #3) 2
Hydrocodone (Hysingla ER) 2
Acetaminophen (paracetamol)-codeine-doxylamine (Maxydol) 1

Show all 11 treatments patients report switching to

Last updated:

21 patient evaluations for Propoxyphene-Acetaminophen

117 members have decided to share their profiles only with other members of PatientsLikeMe.

grandma2009
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grandma2009
Sex: F
Data Quality: 2 stars
Relapse: Moderate
Sensation: Severe
Overall: Moderate
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: moderate
Upper limb: moderate
Walking: severe
I am: vb
I have:
MS

See grandma2009's full Propoxyphene-Acetaminophen history

Feb 18, 2011 (Started Apr 15, 2008)

  • Effectiveness
    Moderate (for Back pain)
  • Effectiveness
    Moderate (for Neck pain)
  • Effectiveness
    Moderate (for Degenerative disc disease (lumbar))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly

Nov 15, 2009 (Started Apr 15, 2008)

  • Effectiveness
    Slight (for Pain in shoulders)
  • Effectiveness
    Slight (for Neck pain)
  • Effectiveness
    None (for Back pain)
  • Effectiveness
    None (for Degenerative disc disease (lumbar))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 8 x napsylate 650 mg-100 mg Daily
Advice & Tips: The reason it didn't work for me at this time was I had a ruptured disc at L5-S1 that was pinching the siatic nerve. I had to go to a stronger pain med.
Cost: < $25 monthly

Feb 23, 2009 (Started Apr 15, 2008)

  • Effectiveness
    Slight (for Back pain)
  • Effectiveness
    Slight (for Pain in shoulders)
  • Effectiveness
    Slight (for Neck pain)
  • Effectiveness
    None (for Degenerative disc disease (lumbar))
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 8 x napsylate 650 mg-100 mg Daily
Cost: < $25 monthly

Oct 23, 2008 (Started Apr 15, 2008)

  • Effectiveness
    Slight (for Back pain)
  • Effectiveness
    Slight (for Pain in shoulders)
  • Effectiveness
    Slight (for Neck pain)
  • Effectiveness
    None (for Degenerative disc disease (lumbar))
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 8 x napsylate 650 mg-100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
lyndeewhatsit2u
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lyndeewhatsit2u
Gender: F
Data Quality: 0 stars
Pain: Little
Fatigue: Little
Sleep: None
Stiffness: Some
function: Most
external_stress: Little
Stickman: little
Description:F52y
CFS:20y Dx
FM:20y Dx
I am: n
I have:
Fibromyalgia

See lyndeewhatsit2u's full Propoxyphene-Acetaminophen history

Dec 1, 2010 (Started Apr 01, 2009)

  • Effectiveness
    Major (for Pain)
  • Side effects
    Mild (Abdominal bloating)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: i would still be taking this if our stupid government had not taken it off the market.
Cost: < $25 monthly
Side effects: Abdominal bloating

  • 0 helpful marks
sharon28753
25900 thumb
sharon28753
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: Little
Sleep: All
Stiffness: All
function: Some
external_stress: Most
Stickman: most
Description:F66y
FM:19y Dx
I am: n
I have:
Fibromyalgia

See sharon28753's full Propoxyphene-Acetaminophen history

Nov 29, 2010 (Started Jul 13, 2010)

  • Effectiveness
    Slight (for Pain in hips)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: was taken off the market
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 21 patient evaluations for Propoxyphene-Acetaminophen