What is Rotigotine?

Category: Prescription Drugs

Most popular types: Neupro Patch

false

Rotigotine, a dopamine agonist drug delivered slowly across the skin by means of a transdermal patch, is worn for 24hrs at a time. The aim is to provide a slow, steady stream of dopamine in order to reduce symptoms and on/off fluctuations.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 349 194
Stiffness/spasticity 19 10
Restless legs syndrome 17 14
Tremor in hands 5 16
Tremor(s) 4 2
Improve mobility 3 3

Show all 23 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
18
Moderate
47
Mild
64
None
76

Commonly reported side effects and conditions associated with Rotigotine

Side effect Patients
Nausea 13
Skin irritation under patch 8
Anxious mood 4
Fatigue 4
Headaches 4
Itching 4

Show all 80 reported side effects

Dosages

Based on patients currently taking Rotigotine

Dosage Patients
6 mg/24 hr daily 11
8 mg daily 8
0.125 mg daily 5
0.25 mg daily 5
2 mg/24 hr daily 5
0.0,833 mg daily 4
0.333 mg daily 4
4 mg/24 hr daily 4
0.0,417 mg daily 2
1 PATCH daily 2

See all 20 dosages

Why patients stopped taking Rotigotine

Multiple reasons could be selected

Reason Patients
Other 66
Side effects too severe 66
Did not seem to work 47
Doctor's advice 33
Expense 9
Course of treatment ended 7
Personal research 3
Change in health plan coverage 2
See all 182 patients who've stopped taking Rotigotine

Duration

Currently taking Rotigotine

Duration Patients
1 - 6 months 4
6 months - 1 year 8
1 - 2 years 7
2 - 5 years 33
5 - 10 years 8
10 years or more 4

Stopped taking Rotigotine

Duration Patients
Less than 1 month 40
1 - 6 months 64
6 months - 1 year 46
1 - 2 years 23
2 - 5 years 10
5 - 10 years 1
10 years or more 2
Adherence
Adherence Evaluations
Always 167
Usually 27
Sometimes 5
Never taken as prescribed 6
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 29
A little hard to take 48
Not at all hard to take 123
Cost per month
Cost per month Evaluations
$200+ 22
$100-199 9
$50-99 33
$25-49 11
< $25 63
Not specified 67

What people switch to and from

Patients started taking Rotigotine after stopping:

Treatment Patients
Pramipexole (Mirapex) 18
Ropinirole (Requip) 14
Carbidopa-Levodopa (Sinemet) 4
Amantadine (Symmetrel) 2
Amitriptyline (Elavil) 1

Show all 10 treatments patients report switching from

Patients stopped taking Rotigotine and switched to:

Treatment Patients
Pramipexole (Mirapex) 10
Carbidopa-Levodopa (Sinemet) 9
Ropinirole (Requip) 9
Carbidopa Levodopa ER (Rytary XR) 4
Amantadine (Symmetrel) 1

Show all 9 treatments patients report switching to

Last updated:

13 patient evaluations for Rotigotine

Jun 30, 2016 (Started Oct 16, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Moderate (leaning to the right)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 4 mg/24 hr Daily
Advice & Tips: I was leaning way to far to the right.
Cost: < $25 monthly

  • 0 helpful marks

Sep 2, 2015 (Started Jul 11, 2013)

  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 1 other Daily
Cost: $50-99 monthly

Sep 2, 2014 (Started Jul 11, 2013)

  • Effectiveness
    Can’t tell (for stiffness/spasticity)
  • Side effects
    Mild (skin irritation under patch)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 4 mg/24 hr Daily
Advice & Tips: secure patch adherence with an overpatch of Hypafix dressing retention by BSN
Cost: $50-99 monthly

  • 0 helpful marks

Apr 14, 2015 (Started Sep 05, 2007)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 4 mg/24 hr Daily
Advice & Tips: Since Neupro again became available in the US, I use it as prescribed, i.e., change patch daily
Cost: $25-49 monthly
Side effects: edema in lower extremities, anxious mood

Jan 31, 2010 (Started Sep 05, 2007)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (anxious mood, edema in lower extremities)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 4 mg Daily
Advice & Tips: due to the cost, I change patches every other day instead of daily and still get the benefits I seek. After 4 weeks on the new dosage my calves & feet were very swollen, but it was mostly gone by the time I saw my neuro 01/28. He commented it was probably my body adjusting to the new dosage. I am also eating more - let's see if that cuts back? :)
Cost: $200+ monthly
Side effects: edema in lower extremities, anxious mood

Mar 11, 2009 (Started Sep 05, 2007)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (anxious mood)
  • Adherence
    Never taken as prescribed
  • Burden
    Somewhat hard to take
Dosage: 2 mg Daily
Advice & Tips: It's the only dopamine agonist I can tolerate (Mirapex & Requip gave me unacceptable side effects). Re: not adhering to the dosing schedule, I cannot afford to use a Neupro patch for just one day, so I use a patch for 2-3 days with good relief. My only downside to Neupro is eating compulsively, but it's *much* better than either Mirapex or Requip.
Cost: $50-99 monthly
Side effects: edema in lower extremities, anxious mood

Aug 27, 2008 (Started Sep 05, 2007)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 2 mg Daily
Advice & Tips: Pray Neupro patches become available again soon in the US.
Cost: $100-199 monthly
Side effects: edema in lower extremities, anxious mood

  • 1 helpful mark
Last updated:
Showing 3 of 13 patient evaluations for Rotigotine