What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,833 1,055
Depressed mood 1,516 720
Persistent depressive disorder (dysthymia) 340 285
Mild Depression 138 55
Anxious mood 114 55
Bipolar Disorder 101 85

Show all 207 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 234
Moderate 333
Mild 545
None 946

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 93
Anxious mood 55
Weight gain 49
Insomnia 46
Headaches 42
Constipation 41

Show all 415 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 133
150 mg daily 130
100 mg daily 86
300 mg/24 hours daily 73
450 mg daily 44
75 mg daily 43
100 mg twice daily 35
150 mg/24 hours daily 27
200 mg daily 26
150 mg twice daily 25

See all 70 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 563
Side effects too severe 480
Doctor's advice 370
Other 250
Course of treatment ended 81
Expense 78
Personal research 68
Change in health plan coverage 36
See all 1389 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 9
1 - 6 months 54
6 months - 1 year 79
1 - 2 years 131
2 - 5 years 174
5 - 10 years 186
10 years or more 129

Stopped taking Bupropion

Duration Patients
Less than 1 month 278
1 - 6 months 330
6 months - 1 year 220
1 - 2 years 203
2 - 5 years 242
5 - 10 years 110
10 years or more 47
Adherence
Adherence Evaluations
Always 1605
Usually 321
Sometimes 45
Never taken as prescribed 87
Burden
Burden Evaluations
Very hard to take 69
Somewhat hard to take 127
A little hard to take 313
Not at all hard to take 1549
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 77
$25-49 158
< $25 1002
Not specified 786

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 66
Fluoxetine (Prozac) 56
Venlafaxine (Effexor XR) 53
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 31

Show all 39 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 39
Sertraline (Zoloft) 31
Venlafaxine (Effexor XR) 24
Citalopram (Celexa) 19
Escitalopram (Lexapro) 19

Show all 40 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,573 members have decided to share their profiles only with other members of PatientsLikeMe.

LadySirona
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LadySirona
Gender: F
Data Quality: 2 stars
Depression: 2
Mania: 1
Emotional: 1
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
57 F
Function: Moderate
Distress: Low
I am: b
I have:
Bipolar Disorder

See LadySirona's full Bupropion history

Mar 9, 2017 (Started Jul 01, 2010)

  • Effectiveness
    Major (for Persistent depressive disorder (dysthymia))
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I poured into pill boxes and took them the same time daily
Cost: < $25 monthly

  • 0 helpful marks
zoomer
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zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: n
I have:
Bipolar I

See zoomer's full Bupropion history

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark
CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 1
External Stress: Moderate
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Bupropion history

Jan 13, 2017 (Started Dec 06, 2016)

  • Effectiveness
    Slight (for Lack of motivation)
  • Effectiveness
    Slight (for Exhaustion)
  • Effectiveness
    Slight (for Excessive sleeping (hypersomnia))
  • Side effects
    Moderate (Muscle twitching (fasciculations), Impulsive behaviors)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion