What is Glyburide-Metformin?

Category: Prescription Drugs

Most popular types: Glucovance

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Glyburide and Metformin is a combination of two antidiabetic agents, a biguanide and a sulfonylurea, used as an adjunct to diet and exercise for the management of type 2 diabetes mellitus (noninsulin dependent, NIDDM).

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 2
Moderate 3
Mild 5
None 11

Commonly reported side effects and conditions associated with Glyburide-Metformin

Side effect Patients
Diarrhea 3
Upset stomach 2
Excessive gas 1
Generalized weakness (asthenia) 1
Headaches 1
Nausea 1

Show all 8 reported side effects

Dosages

Based on patients currently taking Glyburide-Metformin

Dosage Patients
2.5-500 mg twice daily 3
2.5-500 mg daily 1
1,000 mg twice daily 1

Why patients stopped taking Glyburide-Metformin

Multiple reasons could be selected

Reason Patients
Doctor's advice 4
Other 3
Course of treatment ended 2
Did not seem to work 2
Change in health plan coverage 1
Personal research 1
Side effects too severe 1
See all 7 patients who've stopped taking Glyburide-Metformin

Duration

Currently taking Glyburide-Metformin

Duration Patients
2 - 5 years 2
5 - 10 years 3

Stopped taking Glyburide-Metformin

Duration Patients
6 months - 1 year 1
1 - 2 years 1
2 - 5 years 1
5 - 10 years 2
10 years or more 2
Adherence
Adherence Evaluations
Always 15
Usually 5
Sometimes 1
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 1
Somewhat hard to take 5
A little hard to take 1
Not at all hard to take 14
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 0
$25-49 1
< $25 11
Not specified 8

What people switch to and from

Patients started taking Glyburide-Metformin after stopping:

Treatment Patients
Metformin (Glucophage) 3
Insulin Glargine (Lantus) 2
Alprazolam (Xanax) 1
Liraglutide (Victoza) 1
Sitagliptin (Januvia) 1

Patients stopped taking Glyburide-Metformin and switched to:

Treatment Patients
Exenatide (Byetta) 1
Metformin (Glucophage) 1
Last updated:
There are no evaluations for Glyburide-Metformin.