What is Carbidopa Levodopa ER?

Category: Prescription Drugs

Most popular types: Rytary XR

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An extended-release preparation of carbidopa/levodopa formulated to release a lower, smoother dose of medication over an extended period of time.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's Disease 120 153
Stiffness/Spasticity 7 9
MSA (Multiple System Atrophy) 4 5
Dystonia 2 3
Multiple Sclerosis 2 2
Tremor in hands 2 1

Show all 19 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 13
Moderate 25
Mild 48
None 71

Commonly reported side effects and conditions associated with Carbidopa Levodopa ER

Side effect Patients
Jerky movements (dyskinesia) 12
Nausea 7
Dystonia 4
Constipation 3
Balance problems 2
Dizziness 2

Show all 46 reported side effects

Dosages

Based on patients currently taking Carbidopa Levodopa ER

Dosage Patients
50-200 mg daily 6
50 mg-200 mg daily 5
2 x 48.75-195 mg four times daily 4
25-100 mg daily 3
2 x 61.25-245 mg three times daily 3
1 capsule(s) four times daily 2
2 capsule(s) three times daily 2
3 capsule(s) three times daily 2
3 mg three times daily 2
3 capsule(s) four times daily 2

See all 50 dosages

Why patients stopped taking Carbidopa Levodopa ER

Multiple reasons could be selected

Reason Patients
Side effects too severe 12
Did not seem to work 8
Doctor's advice 4
Change in health plan coverage 2
Expense 2
Course of treatment ended 1
Other 1
See all 24 patients who’ve stopped taking Carbidopa Levodopa ER

Duration

Currently taking Carbidopa Levodopa ER

Duration Patients
Less than 1 month 1
1 - 6 months 9
6 months - 1 year 12
1 - 2 years 28
2 - 5 years 16
5 - 10 years 8
10 years or more 2

Stopped taking Carbidopa Levodopa ER

Duration Patients
Less than 1 month 4
1 - 6 months 9
6 months - 1 year 3
1 - 2 years 5
2 - 5 years 3
Adherence
Adherence Evaluations
Always 127
Usually 26
Sometimes 2
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 13
A little hard to take 31
Not at all hard to take 110
Cost per month
Cost per month Evaluations
$200+ 14
$100-199 12
$50-99 21
$25-49 26
< $25 51
Not specified 33

What people switch to and from

Patients started taking Carbidopa Levodopa ER after stopping:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 51
Carbidopa-Entacapone-Levodopa (Stalevo) 11
Entacapone (Comtan) 9
Carbidopa-Levodopa CR (Sinemet CR) 5
Pramipexole (Mirapex) 3

Show all 11 treatments patients report switching from

Patients stopped taking Carbidopa Levodopa ER and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 8
Carbidopa-Entacapone-Levodopa (Stalevo) 3
Carbidopa-Levodopa CR (Sinemet CR) 2
Carbidopa Levodopa ER (Rytary XR) 2
Rotigotine (Neupro Patch) 1
Last updated:

10 patient evaluations for Carbidopa Levodopa ER

81 members have decided to share their profiles only with other members of PatientsLikeMe.

rose5
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rose5
Sex: F
Data Quality: 3 stars
On
Mouth/throat: moderate
Arms: moderate
Chest: severe
Legs: severe
I am: vb
I have:
Parkinson's

See rose5's full Carbidopa Levodopa ER history

May 19, 2017 (Started May 04, 2015)

  • Effectiveness
    None (for Parkinson's Disease)
  • Side effects
    Severe (Falls, Inability to walk, Dizziness/walking like I'm drunk, Dystonia, Dizziness)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 48.75 mg Three times daily
Advice & Tips: MY DOCTOR PUT ME BACK ON STALEVO 200MG BECAUSE RYTARY HAD TOO MANY SIDE EFFECTS
Cost: $100-199 monthly

Dec 28, 2016 (Started May 04, 2015)

  • Effectiveness
    Slight (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 48.75 mg Three times daily
Advice & Tips: UNFORTUNATELY RYTARY DOES NOT HELP ME.
Cost: $100-199 monthly

Apr 23, 2016 (Started May 04, 2015)

  • Effectiveness
    Slight (for Parkinson's Disease)
  • Side effects
    Mild (Falls, Inability to walk, Dizziness/walking like I'm drunk, Dystonia, Dizziness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 48.75 mg Three times daily
Advice & Tips: DOES NOT SEEM TO BE WORKING
Cost: $100-199 monthly

Aug 11, 2015 (Started May 04, 2015)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    Moderate (Falls, Inability to walk, Dizziness/walking like I'm drunk, Dystonia, Dizziness)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 48.75 mg Three times daily
Advice & Tips: I SWITCHED FROM STALEVO TO RYTARY BUT HAVE SEEN LITTLE IMPROVEMENT.
Cost: $100-199 monthly

  • 0 helpful marks
browncat87
58847 thumb
browncat87
Sex: F
Data Quality: 3 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: mild
I am: n
I have:
Parkinson's

See browncat87's full Carbidopa Levodopa ER history

May 5, 2017 (Started Apr 05, 2016)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 capsule(s) Four times daily
Advice & Tips: I like feeling as normal as possible. and my meds make it posssible/
Cost: $50-99 monthly

Oct 22, 2016 (Started Apr 05, 2016)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    Mild (Nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 23.75-95 mg Twice daily
Advice & Tips: it takes a while to work into the system and my muscles are more loose and supple while it is "on"
Cost: $50-99 monthly

  • 0 helpful marks
Tulabee
14440 thumb
Tulabee
Sex: F
Data Quality: 3 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: mild
I am: g
I have:
Parkinson's

See Tulabee's full Carbidopa Levodopa ER history

Mar 6, 2017 (Started Jul 31, 2015)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Jerky movements (dyskinesia))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 48.75-195 mg Four times daily
Advice & Tips: I am happy with the effectiveness with Rytary compared to Sinemet. I tried 4x a day, but i got wiggly in the evening. Yet, if I had to be out and about in the evening, I would take the 4th dose. I wonder if I'm more wakeful with Rytary and need less modafinil?
Cost: < $25 monthly

Sep 23, 2016 (Started Jul 31, 2015)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Jerky movements (dyskinesia))
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 2 x 48.75-195 mg Four times daily
Advice & Tips: I noticed a lack of effectiveness in early August. Neurologist said to add one 25/100 carbidopa/levadopa to the the 36.25/145 mg Rytary dose. After couple weeks it seemed to be enough. At that point I started one dose 48.75-195 mg four times daily. It is acceptable. I take it every 4 hours , starting at 6am. Sometimes I don't take the 6pm dose.
Cost: < $25 monthly

Jul 21, 2016 (Started Jul 31, 2015)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Jerky movements (dyskinesia))
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 36.25-145 mg Four times daily
Advice & Tips: Rytary has smoothed out the peaks and valleys. It took about 6 weeks of futzing with the timing. I was pleasantly surprised. It makes it easier to predict the days outings I'm able to trust my body. Note: my insurance is a HDHP so my cost varies from 100% of negotiated cost, to 20%, to 0%.
Cost: $25-49 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 10 patient evaluations for Carbidopa Levodopa ER