What is Zonisamide?

Category: Prescription Drugs

Most popular types: Zonegran

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Zonisamide is an anticonvulsant drug that may be used in combination with other anti-seizure medications to treat partial seizures. 

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 308 164
Migraine headaches 47 23
Seizures (complex partial) 38 30
Nerve pain (neuralgia) 9 1
Seizures 8 1
Seizures (grand mal or tonic-clonic) 8 7

Show all 55 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
53
Moderate
53
Mild
43
None
60

Commonly reported side effects and conditions associated with Zonisamide

Side effect Patients
Loss of appetite 8
Drowsiness 7
Fatigue 7
Memory problems 7
Weight loss 7
Headaches 6

Show all 124 reported side effects

Dosages

Based on patients currently taking Zonisamide

Dosage Patients
100 mg daily 7
400 mg daily 6
200 mg daily 5
300 mg daily 4
50 mg daily 3
50 mg twice daily 2
100 mg twice daily 2
500 mg daily 2
600 mg daily 2
25 mg daily 1

See all 18 dosages

Why patients stopped taking Zonisamide

Multiple reasons could be selected

Reason Patients
Side effects too severe 54
Did not seem to work 48
Doctor's advice 42
Other 9
Expense 6
Course of treatment ended 5
Personal research 3
Change in health plan coverage 2
See all 121 patients who've stopped taking Zonisamide

Duration

Currently taking Zonisamide

Duration Patients
1 - 6 months 1
6 months - 1 year 3
1 - 2 years 6
2 - 5 years 12
5 - 10 years 15
10 years or more 5

Stopped taking Zonisamide

Duration Patients
Less than 1 month 31
1 - 6 months 24
6 months - 1 year 17
1 - 2 years 19
2 - 5 years 18
5 - 10 years 11
10 years or more 1
Adherence
Adherence Evaluations
Always 172
Usually 23
Sometimes 4
Never taken as prescribed 10
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 14
A little hard to take 26
Not at all hard to take 155
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 4
$50-99 10
$25-49 16
< $25 82
Not specified 93

What people switch to and from

Patients started taking Zonisamide after stopping:

Treatment Patients
Topiramate (Topamax) 10
Lamotrigine (Lamictal) 5
Levetiracetam (Keppra) 4
Phenytoin (Dilantin) 4
Gabapentin (Neurontin) 3

Show all 13 treatments patients report switching from

Patients stopped taking Zonisamide and switched to:

Treatment Patients
Levetiracetam (Keppra) 2
Topiramate (Topamax) 2
Botulinum Toxin Type A (Botox) 1
Divalproex sodium (Depakote) 1
Duloxetine (Cymbalta) 1

Show all 9 treatments patients report switching to

Last updated:

16 patient evaluations for Zonisamide

Jan 3, 2017 (Started Oct 09, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Dec 16, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Can't tell (for epilepsy)
  • Side effects
    Severe (depression with suicidal thoughts, mood swings, anger, numbness and tingling in hands, loss of appetite, increased anxiety, suicidal thoughts or urges)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

Jun 30, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Can't tell (for epilepsy)
  • Side effects
    Severe (depression with suicidal thoughts, mood swings, anger, numbness and tingling in hands, loss of appetite, increased anxiety, suicidal thoughts or urges)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Sep 4, 2013 (Started Aug 02, 2013)

  • Effectiveness
    Can't tell (for migraine headaches)
  • Side effects
    Moderate (nightmares, suicidal, depressed mood, headaches)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 16 patient evaluations for Zonisamide