What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
bipolar disorder 1,415 826
epilepsy 1,088 514
bipolar II disorder 710 442
bipolar I disorder 426 267
Depressed mood 155 102
borderline personality disorder 147 96

Show all 217 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 252
Moderate 403
Mild 569
None 903

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 70
Headaches 69
Weight gain 68
Nausea 51
Insomnia 46
Problems concentrating 45

Show all 519 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 153
100 mg daily 97
25 mg daily 61
150 mg daily 58
200 mg twice daily 49
100 mg twice daily 43
50 mg daily 41
400 mg daily 39
300 mg daily 36
150 mg twice daily 26

See all 76 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 425
Did not seem to work 387
Doctor's advice 254
Other 188
Expense 65
Personal research 54
Course of treatment ended 40
Change in health plan coverage 32
See all 968 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 14
1 - 6 months 49
6 months - 1 year 50
1 - 2 years 120
2 - 5 years 218
5 - 10 years 189
10 years or more 134

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 206
1 - 6 months 229
6 months - 1 year 155
1 - 2 years 131
2 - 5 years 163
5 - 10 years 86
10 years or more 15
Adherence
Adherence Evaluations
Always 1731
Usually 274
Sometimes 47
Never taken as prescribed 75
Burden
Burden Evaluations
Very hard to take 94
Somewhat hard to take 193
A little hard to take 355
Not at all hard to take 1485
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 48
$50-99 64
$25-49 115
< $25 985
Not specified 873

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 80
Quetiapine (Seroquel) 45
Divalproex sodium (Depakote) 43
Aripiprazole (Abilify) 38
Bupropion (Wellbutrin XL) 19

Show all 53 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 37
Quetiapine (Seroquel) 20
Aripiprazole (Abilify) 19
Divalproex sodium (Depakote) 11
Lurasidone (Latuda) 10

Show all 51 treatments patients report switching to

Last updated:

138 patient evaluations for Lamotrigine

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Can’t tell (for epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Slight (for epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

  • 0 helpful marks

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
Last updated:
Showing 3 of 138 patient evaluations for Lamotrigine