What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 1,490 860
Epilepsy 1,096 524
Bipolar II disorder 747 458
Bipolar I disorder 438 276
Depressed mood 159 106
Major depressive disorder 155 120

Show all 204 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 267
Moderate 411
Mild 586
None 936

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Weight gain 70
Dizziness 69
Headaches 66
Rashes (redness, swelling) 53
Nausea 48
Fatigue 46

Show all 522 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 135
100 mg daily 94
25 mg daily 56
200 mg twice daily 51
150 mg daily 50
300 mg daily 40
100 mg twice daily 33
400 mg daily 30
50 mg daily 29
150 mg twice daily 21

See all 64 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 447
Did not seem to work 400
Doctor's advice 265
Other 194
Expense 67
Personal research 54
Course of treatment ended 42
Change in health plan coverage 35
See all 1006 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 10
1 - 6 months 60
6 months - 1 year 51
1 - 2 years 93
2 - 5 years 188
5 - 10 years 158
10 years or more 126

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 218
1 - 6 months 239
6 months - 1 year 159
1 - 2 years 134
2 - 5 years 170
5 - 10 years 88
10 years or more 15
Adherence
Adherence Evaluations
Always 1798
Usually 280
Sometimes 47
Never taken as prescribed 75
Burden
Burden Evaluations
Very hard to take 96
Somewhat hard to take 199
A little hard to take 364
Not at all hard to take 1541
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 49
$50-99 65
$25-49 118
< $25 1021
Not specified 905

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 88
Quetiapine (Seroquel) 48
Divalproex sodium (Depakote) 46
Aripiprazole (Abilify) 40
Topiramate (Topamax) 21

Show all 54 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 39
Aripiprazole (Abilify) 22
Quetiapine (Seroquel) 22
Divalproex sodium (Depakote) 12
Lurasidone (Latuda) 11

Show all 58 treatments patients report switching to

Last updated:

139 patient evaluations for Lamotrigine

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for seizures)
  • Effectiveness
    Can’t tell (for epilepsy)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for seizures)
  • Effectiveness
    Slight (for epilepsy)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

  • 0 helpful marks

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
Last updated:
Showing 3 of 139 patient evaluations for Lamotrigine