What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,387 3,231
Depressed mood 2,087 1,239
Major depressive disorder 1,936 1,183
Generalized anxiety disorder 801 574
Myalgic encephalomyelitis/chronic fatigue syndrome 692 384
Pain 539 320

Show all 321 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 936
Moderate 1,025
Mild 1,158
None 1,790

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 336
Nausea 287
Decreased sex drive (libido) 185
Dry mouth 169
Dizziness 160
Sweating increased 101

Show all 583 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 378
30 mg daily 131
120 mg daily 122
90 mg daily 70
60 mg twice daily 68
20 mg daily 52
30 mg twice daily 24
40 mg daily 15
120 mg twice daily 11
20 mg twice daily 9

See all 38 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1759
Did not seem to work 1560
Doctor's advice 592
Expense 445
Other 436
Personal research 177
Change in health plan coverage 162
Course of treatment ended 70
See all 3507 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
1 - 6 months 39
6 months - 1 year 34
1 - 2 years 108
2 - 5 years 289
5 - 10 years 308
10 years or more 166

Stopped taking Duloxetine

Duration Patients
Less than 1 month 816
1 - 6 months 936
6 months - 1 year 554
1 - 2 years 497
2 - 5 years 526
5 - 10 years 157
10 years or more 38
Adherence
Adherence Evaluations
Always 4111
Usually 436
Sometimes 75
Never taken as prescribed 287
Burden
Burden Evaluations
Very hard to take 303
Somewhat hard to take 372
A little hard to take 577
Not at all hard to take 3657
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 190
$50-99 435
$25-49 691
< $25 1590
Not specified 1877

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 135
Venlafaxine (Effexor XR) 125
Sertraline (Zoloft) 117
Citalopram (Celexa) 100

Show all 74 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 78
Venlafaxine (Effexor XR) 71
Gabapentin (Neurontin) 59
Escitalopram (Lexapro) 39
Bupropion (Wellbutrin XL) 37

Show all 77 treatments patients report switching to

Last updated:

320 patient evaluations for Duloxetine

Apr 16, 2005 (Started Mar 15, 2005)

  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Severe (withdrawal effects, suicidal)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 30 mg Daily
Advice & Tips: AKA drug of death. Horrific withdrawal after only one month. Suicidal.
Side effects: suicidal, withdrawal effects

  • 0 helpful marks

Jan 1, 2001 (Started )

  • Effectiveness
    None (for pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 2 of 320 patient evaluations for Duloxetine