What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

false

Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,345 3,204
Depressed mood 2,076 1,230
Major depressive disorder 1,917 1,164
Generalized anxiety disorder 798 572
Myalgic encephalomyelitis/chronic fatigue syndrome 693 385
Pain 535 320

Show all 327 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 931
Moderate 1,017
Mild 1,146
None 1,767

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 335
Nausea 287
Decreased sex drive (libido) 184
Dry mouth 169
Dizziness 160
Sweating increased 100

Show all 733 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 407
30 mg daily 152
120 mg daily 141
90 mg daily 76
60 mg twice daily 67
20 mg daily 61
30 mg twice daily 29
40 mg daily 16
20 mg twice daily 11
120 mg twice daily 11

See all 42 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1749
Did not seem to work 1548
Doctor's advice 584
Expense 445
Other 435
Personal research 176
Change in health plan coverage 160
Course of treatment ended 69
See all 3485 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 2
1 - 6 months 19
6 months - 1 year 95
1 - 2 years 138
2 - 5 years 293
5 - 10 years 324
10 years or more 164

Stopped taking Duloxetine

Duration Patients
Less than 1 month 814
1 - 6 months 932
6 months - 1 year 549
1 - 2 years 498
2 - 5 years 517
5 - 10 years 156
10 years or more 36
Adherence
Adherence Evaluations
Always 4065
Usually 434
Sometimes 75
Never taken as prescribed 287
Burden
Burden Evaluations
Very hard to take 300
Somewhat hard to take 369
A little hard to take 575
Not at all hard to take 3617
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 190
$50-99 434
$25-49 691
< $25 1565
Not specified 1855

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 130
Venlafaxine (Effexor XR) 123
Sertraline (Zoloft) 111
Citalopram (Celexa) 99

Show all 74 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 78
Venlafaxine (Effexor XR) 70
Gabapentin (Neurontin) 58
Escitalopram (Lexapro) 38
Bupropion (Wellbutrin XL) 37

Show all 78 treatments patients report switching to

Last updated:

321 patient evaluations for Duloxetine

Mar 19, 2006 (Started Apr 01, 2003)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: This was originally given to me as an anti-depressent that is supposed to help with pain. I am not aware of any negative side effects. While I am still always in pain, I can only assume, it would be alot worse without the Cymbalta. The unexpected benefit came as a result of my dosage being doubled for Fibro. Given a number of constant and occasionally overwhelming pressures I am living with, I find it remarkable I haven't gone into any deep depressions and I believe it due to the additional dosage
Cost: < $25 monthly

  • 0 helpful marks

Apr 16, 2005 (Started Mar 15, 2005)

  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Severe (withdrawal effects, suicidal)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 30 mg Daily
Advice & Tips: AKA drug of death. Horrific withdrawal after only one month. Suicidal.
Side effects: suicidal, withdrawal effects

  • 0 helpful marks

Jan 1, 2001 (Started )

  • Effectiveness
    None (for pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 321 patient evaluations for Duloxetine