What is Mercaptopurine?

Category: Prescription Drugs

Most popular types: Purinethol

false

Mercaptopurine is an antineoplastic and immunosuppressant agent used for the treatment (maintenance and induction) of acute lymphoblastic leukemia. It is also used as a steroid-sparing agent for corticosteroid-dependent Crohn's disease and ulcerative colitis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Crohn's disease 43 20
Ulcerative colitis 8 8
Autoimmune hepatitis 2 2
Systemic lupus erythematosus 2 1
Acute lymphocytic leukemia 1 0

Show all 13 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
9
Moderate
9
Mild
4
None
14

Commonly reported side effects and conditions associated with Mercaptopurine

Side effect Patients
Nausea 5
Fatigue 4
Dizziness 3
Nausea and vomiting 3
Bruising 2
Headaches 2

Show all 36 reported side effects

Dosages

Based on patients currently taking Mercaptopurine

Dosage Patients
75 mg daily 3
50 mg daily 2
25 mg daily 1
100 mg daily 1
2,500 mg daily 1

Why patients stopped taking Mercaptopurine

Multiple reasons could be selected

Reason Patients
Side effects too severe 15
Doctor's advice 9
Did not seem to work 8
Other 4
Course of treatment ended 2
Personal research 2
Change in health plan coverage 1
Expense 1
See all 29 patients who've stopped taking Mercaptopurine

Duration

Currently taking Mercaptopurine

Duration Patients
6 months - 1 year 3
1 - 2 years 1
2 - 5 years 2
10 years or more 2

Stopped taking Mercaptopurine

Duration Patients
Less than 1 month 8
1 - 6 months 2
6 months - 1 year 2
1 - 2 years 3
2 - 5 years 5
5 - 10 years 8
10 years or more 1
Adherence
Adherence Evaluations
Always 27
Usually 6
Sometimes 0
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 1
A little hard to take 5
Not at all hard to take 27
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 2
< $25 13
Not specified 20

What people switch to and from

Patients started taking Mercaptopurine after stopping:

Treatment Patients
Azathioprine (Imuran) 3
Prednisone (Deltasone) 3
Mesalamine (Pentasa) 2
Adalimumab (Humira) 1
Mesalamine (rectal) (Canasa) 1

Patients stopped taking Mercaptopurine and switched to:

Treatment Patients
Adalimumab (Humira) 4
Azathioprine (Imuran) 1
Budesonide (Pulmicort) 1
Infliximab (Remicade) 1
Mycophenolate mofetil (CellCept) 1

Show all 6 treatments patients report switching to

Last updated:

2 patient evaluations for Mercaptopurine

Feb 15, 2013 (Started Feb 15, 2013)

  • Effectiveness
    Slight (for Crohn's disease)
  • Side effects
    Severe (nausea and vomiting)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Dosage: 50 mg Daily
Advice & Tips: Possible pancreatitis. No-go.

  • 0 helpful marks

Dec 14, 2009 (Started Nov 20, 2009)

  • Effectiveness
    Can't tell (for ulcerative colitis)
  • Side effects
    Moderate (nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Side effects: nausea

  • 0 helpful marks
Last updated:
Showing 2 of 2 patient evaluations for Mercaptopurine