What is Glycopyrrolate?

Category: Prescription Drugs

Most popular types: Robinul Glycopyrronium Robinul Forte

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Glycopyrrolate is an anticholinergic drug which slows the activity of the salivary glands, stomach and intestinal tract, thus relieving cramping and reducing acid secretion. It is commonlu used in the treatment of peptic ulcers, but also has a specific use in ALS/MND of reducing excess saliva.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Excess saliva 93 39
ALS (Amyotrophic Lateral Sclerosis) 12 8
Excess mucus 4 3
Excessive sweating 3 1
Hyperhydrosis Disorder 3 3
Bowel irritability 2 0

Show all 18 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 6
Moderate 4
Mild 7
None 37

Commonly reported side effects and conditions associated with Glycopyrrolate

Side effect Patients
Dry mouth 4
Constipation 3
Dry eyes 3
Diarrhea 1
Dry throat 1
Excessive dry mouth 1

Show all 9 reported side effects

Dosages

Based on patients currently taking Glycopyrrolate

Dosage Patients
2 mg twice daily 4
1 mg twice daily 3
2 mg daily 2
1mg as needed 2
0.8 mg daily 1
1 mg daily 1
1 mg three times daily 1
3 mg daily 1
1 mg four times daily 1
2 mg three times daily 1

Why patients stopped taking Glycopyrrolate

Multiple reasons could be selected

Reason Patients
Did not seem to work 19
Side effects too severe 8
Doctor's advice 2
Other 2
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
Personal research 1
See all 31 patients who’ve stopped taking Glycopyrrolate

Duration

Currently taking Glycopyrrolate

Duration Patients
1 - 6 months 1
6 months - 1 year 2
1 - 2 years 9
2 - 5 years 4
5 - 10 years 1
10 years or more 1

Stopped taking Glycopyrrolate

Duration Patients
Less than 1 month 11
1 - 6 months 9
6 months - 1 year 5
1 - 2 years 3
2 - 5 years 3
Adherence
Adherence Evaluations
Always 40
Usually 7
Sometimes 3
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 1
A little hard to take 7
Not at all hard to take 44
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 3
$25-49 1
< $25 24
Not specified 26

What people switch to and from

Patients started taking Glycopyrrolate after stopping:

Treatment Patients
Dicyclomine (Bentyl) 1

Patients stopped taking Glycopyrrolate and switched to:

Treatment Patients
Amitriptyline (Elavil) 2
Atropine ophthalmic 1
Botulinum Toxin Type A (Botox) 1
Scopolamine Patch (Transderm Scop) 1
Last updated:

12 patient evaluations for Glycopyrrolate

41 members have decided to share their profiles only with other members of PatientsLikeMe.

AcesHigh
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AcesHigh
Sex: M
Data Quality: 2 stars
Bulbar: moderate
Arms: severe
Chest: moderate
Legs: severe
I am: g
I have:
ALS

See AcesHigh's full Glycopyrrolate history

Dec 24, 2015 (Started Oct 12, 2015)

  • Effectiveness
    Moderate (for Excess saliva)
  • Effectiveness
    Moderate (for ALS (Amyotrophic Lateral Sclerosis))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
bobert54
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bobert54
Sex: M
Data Quality: 2 stars
On
Mouth/throat: moderate
Arms: mild
Chest: none
Legs: mild
I am: n
I have:
Parkinson's

See bobert54's full Glycopyrrolate history

May 12, 2015 (Started Apr 14, 2015)

  • Effectiveness
    Slight (for Excess saliva)
  • Side effects
    Severe (Constipation)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 1 mg Twice daily
Advice & Tips: The slight benefit in decreased saliva wasn't worth the severe constipation.

Mar 7, 2015 (Started Apr 14, 2015)

  • Effectiveness
    Slight (for Excess saliva)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 0 helpful marks
thjuland
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thjuland
Sex: M
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: none
Speech: none
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: n
I have:
MS

See thjuland's full Glycopyrrolate history

Apr 27, 2014 (Started Feb 20, 2012)

  • Effectiveness
    Moderate (for GERD (Gastroesophageal reflux disease))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

Mar 22, 2012 (Started Feb 20, 2012)

  • Effectiveness
    Moderate (for GERD (Gastroesophageal reflux disease))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Advice & Tips: My doctor suggested taking Glycopyrrolate with the Omeprazole, since alone the first one provides insufficient relief. Seems their actions compliment each other's, which provides additional acid reflux relief. Now after a month of taking both, most days I have very good results and have been able to eliminate relying on Alka Seltzer or baking soda.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 12 patient evaluations for Glycopyrrolate