What is Glycopyrrolate?

Category: Prescription Drugs

Most popular types: Robinul Glycopyrronium Robinul Forte

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Glycopyrrolate is an anticholinergic drug which slows the activity of the salivary glands, stomach and intestinal tract, thus relieving cramping and reducing acid secretion. It is commonlu used in the treatment of peptic ulcers, but also has a specific use in ALS/MND of reducing excess saliva.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Excess saliva 101 47
Amyotrophic lateral sclerosis 15 11
Excess mucus 4 3
Excessive sweating 3 1
Hyperhidrosis disorder 3 3
Bowel irritability 2 0

Show all 18 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 6
Moderate 5
Mild 8
None 43

Commonly reported side effects and conditions associated with Glycopyrrolate

Side effect Patients
Dry mouth 4
Constipation 3
Dry eyes 3
Bladder problems 1
Diarrhea 1
Dry mouth at night 1

Show all 12 reported side effects

Dosages

Based on patients currently taking Glycopyrrolate

Dosage Patients
1 mg twice daily 5
2 mg twice daily 3
2 mg daily 2
1 mg daily 1
1 tsp. daily 1
1 mg three times daily 1
3 mg daily 1
4 mg daily 1
2 mg three times daily 1
5 mg twice daily 1

See all 11 dosages

Why patients stopped taking Glycopyrrolate

Multiple reasons could be selected

Reason Patients
Did not seem to work 19
Side effects too severe 8
Doctor's advice 2
Other 2
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
Personal research 1
See all 31 patients who've stopped taking Glycopyrrolate

Duration

Currently taking Glycopyrrolate

Duration Patients
1 - 6 months 3
6 months - 1 year 3
1 - 2 years 5
2 - 5 years 5
5 - 10 years 2

Stopped taking Glycopyrrolate

Duration Patients
Less than 1 month 11
1 - 6 months 9
6 months - 1 year 5
1 - 2 years 3
2 - 5 years 3
Adherence
Adherence Evaluations
Always 48
Usually 7
Sometimes 3
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 2
A little hard to take 10
Not at all hard to take 48
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 3
$25-49 5
< $25 25
Not specified 28

What people switch to and from

Patients started taking Glycopyrrolate after stopping:

Treatment Patients
Amitriptyline (Elavil) 1
Dextromethorphan-Quinidine (Nuedexta) 1
Dicyclomine (Bentyl) 1

Patients stopped taking Glycopyrrolate and switched to:

Treatment Patients
Amitriptyline (Elavil) 2
Atropine ophthalmic 1
Botulinum Toxin Type A (Botox) 1
Scopolamine Patch (Transderm Scop) 1
Last updated:

12 patient evaluations for Glycopyrrolate

Dec 24, 2015 (Started Oct 12, 2015)

  • Effectiveness
    Moderate (for excess saliva)
  • Effectiveness
    Moderate (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 12, 2015 (Started Apr 14, 2015)

  • Effectiveness
    Slight (for excess saliva)
  • Side effects
    Severe (constipation)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 1 mg Twice daily
Advice & Tips: The slight benefit in decreased saliva wasn't worth the severe constipation.

Mar 7, 2015 (Started Apr 14, 2015)

  • Effectiveness
    Slight (for excess saliva)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 0 helpful marks

Apr 27, 2014 (Started Feb 20, 2012)

  • Effectiveness
    Moderate (for gastroesophageal reflux disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

Mar 22, 2012 (Started Feb 20, 2012)

  • Effectiveness
    Moderate (for gastroesophageal reflux disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Advice & Tips: My doctor suggested taking Glycopyrrolate with the Omeprazole, since alone the first one provides insufficient relief. Seems their actions compliment each other's, which provides additional acid reflux relief. Now after a month of taking both, most days I have very good results and have been able to eliminate relying on Alka Seltzer or baking soda.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 12 patient evaluations for Glycopyrrolate