What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

false

Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 579 271
Bipolar disorder 382 220
Migraine headaches 108 55
Bipolar II disorder 56 37
Bipolar I disorder 48 34
Bipolar manic episodes 45 34

Show all 117 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 182
Moderate 194
Mild 187
None 177

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 143
Hair loss 45
Fatigue 39
Drowsiness 26
Tremor in hands 21
Nausea 18

Show all 265 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
500 mg daily 20
1,000 mg daily 20
250 mg daily 15
500 mg twice daily 13
250 mg twice daily 9
750 mg daily 8
1,500 mg daily 7
2,000 mg daily 6
1,250 mg daily 5
500 mg four times daily 5

See all 30 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 346
Did not seem to work 248
Doctor's advice 172
Other 106
Personal research 35
Expense 31
Course of treatment ended 26
Change in health plan coverage 11
See all 639 patients who've stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
1 - 6 months 5
6 months - 1 year 19
1 - 2 years 20
2 - 5 years 24
5 - 10 years 40
10 years or more 30

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 124
1 - 6 months 143
6 months - 1 year 74
1 - 2 years 77
2 - 5 years 125
5 - 10 years 51
10 years or more 55
Adherence
Adherence Evaluations
Always 581
Usually 115
Sometimes 22
Never taken as prescribed 22
Burden
Burden Evaluations
Very hard to take 56
Somewhat hard to take 117
A little hard to take 117
Not at all hard to take 450
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 19
$50-99 33
$25-49 60
< $25 290
Not specified 319

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 40
Lamotrigine (Lamictal) 20
Topiramate (Topamax) 16
Aripiprazole (Abilify) 10
Carbamazepine (Tegretol) 6

Show all 46 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 32
Carbamazepine (Tegretol) 11
Levetiracetam (Keppra) 10
Lithium Carbonate (Lithium Carbonate ER) 10
Oxcarbazepine (Trileptal) 9

Show all 36 treatments patients report switching to

Last updated:

65 patient evaluations for Divalproex sodium

Last updated:
Showing 0 of 65 patient evaluations for Divalproex sodium