What is Leflunomide?

Category: Prescription Drugs

Most popular types: Arava

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Leflunomide is a disease modifying antirheumatic drug used to treat active rheumatoid arthritis to reduce symptoms, retard structural damage and improve physical function. Also use as to prevent rejection in organ transplants.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid Arthritis (RA) 283 105
Systemic Lupus Erythematosus 30 14
Rheumatoid Arthritis 19 10
Psoriatic Arthritis 16 13
BK virus 4 0
Joint pain 4 2

Show all 31 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 35
Moderate 34
Mild 26
None 45

Commonly reported side effects and conditions associated with Leflunomide

Side effect Patients
Diarrhea 16
Nausea 11
Hair loss 9
Elevated liver enzymes 4
Upset stomach 4
Weight loss 4

Show all 62 reported side effects

Dosages

Based on patients currently taking Leflunomide

Dosage Patients
20 mg daily 15
10 mg daily 7
100 mg daily 2
10 mg m,w,f 1
20 mg twice daily 1

Why patients stopped taking Leflunomide

Multiple reasons could be selected

Reason Patients
Side effects too severe 74
Did not seem to work 63
Doctor's advice 56
Other 12
Expense 6
Personal research 4
Course of treatment ended 3
See all 146 patients who’ve stopped taking Leflunomide

Duration

Currently taking Leflunomide

Duration Patients
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 8
2 - 5 years 9
5 - 10 years 5
10 years or more 2

Stopped taking Leflunomide

Duration Patients
Less than 1 month 22
1 - 6 months 48
6 months - 1 year 37
1 - 2 years 19
2 - 5 years 16
5 - 10 years 5
Adherence
Adherence Evaluations
Always 123
Usually 8
Sometimes 2
Never taken as prescribed 7
Burden
Burden Evaluations
Very hard to take 11
Somewhat hard to take 8
A little hard to take 14
Not at all hard to take 107
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 2
$50-99 7
$25-49 12
< $25 64
Not specified 53

What people switch to and from

Patients started taking Leflunomide after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 24
Hydroxychloroquine (Plaquenil) 16
Sulfasalazine (Salazopyrin) 5
Azathioprine (Imuran) 3
Prednisone (Deltasone) 3

Show all 10 treatments patients report switching from

Patients stopped taking Leflunomide and switched to:

Treatment Patients
Adalimumab (Humira Pen) 6
Methotrexate (Apo-Methotrexate) 6
Etanercept (Enbrel SureClick) 5
Azathioprine (Imuran) 4
Belimumab (Benlysta) 2

Show all 12 treatments patients report switching to

Last updated:

5 patient evaluations for Leflunomide

116 members have decided to share their profiles only with other members of PatientsLikeMe.

gummitarzan
46280 thumb
gummitarzan
Data Quality: 3 stars
  • Gender: M
  • Age: 70
Condition: Rheumatoid Arthritis (RA) 5 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: b
I have:
Rheumatoid Arthritis (RA)

See gummitarzan's full Leflunomide history

Dec 6, 2016 (Started Jan 30, 2014)

  • Effectiveness
    None (for Rheumatoid Arthritis (RA))
  • Side effects
    Moderate (Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

May 15, 2014 (Started Jan 30, 2014)

  • Effectiveness
    None (for Rheumatoid Arthritis (RA))
  • Side effects
    Moderate (Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily

  • 0 helpful marks
25yrRA
34004 thumb
25yrRA
Data Quality: 1 star
  • Gender: F
  • Age: 55
Condition: Rheumatoid Arthritis (RA) 20 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: g
I have:
Rheumatoid Arthritis (RA)

See 25yrRA's full Leflunomide history

Mar 16, 2012 (Started Dec 12, 2011)

  • Effectiveness
    None (for Rheumatoid Arthritis (RA))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
andreamegan
34924 thumb
andreamegan
Data Quality: 1 star
  • Gender: F
  • Age: 29
Condition: Rheumatoid Arthritis (RA) 4 additional condition(s)
Quality of life:
  • Mental: Moderate
  • Physical: Moderate
I am: b
I have:
Rheumatoid Arthritis (RA)

See andreamegan's full Leflunomide history

Jul 4, 2011 (Started Apr 15, 2011)

  • Effectiveness
    Can’t tell (for Rheumatoid Arthritis (RA))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 20 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Leflunomide