What is Leflunomide?

Category: Prescription Drugs

Most popular types: Arava

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Leflunomide is a disease modifying antirheumatic drug used to treat active rheumatoid arthritis to reduce symptoms, retard structural damage and improve physical function. Also use as to prevent rejection in organ transplants.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 332 128
Systemic lupus erythematosus 34 21
Psoriatic arthritis 15 15
Arthritis pain 4 1
BK virus 4 0

Show all 27 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 37
Moderate 42
Mild 39
None 54

Commonly reported side effects and conditions associated with Leflunomide

Side effect Patients
Diarrhea 19
Nausea 12
Hair loss 11
Headaches 5
Elevated liver enzymes 4
Weight loss 4

Show all 66 reported side effects

Dosages

Based on patients currently taking Leflunomide

Dosage Patients
20 mg daily 37
10 mg daily 13
100 mg daily 2
10 mg m,w,f 1
10 mg twice daily 1
20 mg twice daily 1
60 mg daily 1
200 mg daily 1
400 mg daily 1

Why patients stopped taking Leflunomide

Multiple reasons could be selected

Reason Patients
Side effects too severe 87
Did not seem to work 72
Doctor's advice 61
Other 17
Expense 7
Personal research 5
Course of treatment ended 4
See all 175 patients who've stopped taking Leflunomide

Duration

Currently taking Leflunomide

Duration Patients
1 - 6 months 6
6 months - 1 year 6
1 - 2 years 10
2 - 5 years 21
5 - 10 years 14
10 years or more 4

Stopped taking Leflunomide

Duration Patients
Less than 1 month 35
1 - 6 months 54
6 months - 1 year 39
1 - 2 years 22
2 - 5 years 17
5 - 10 years 7
10 years or more 2
Adherence
Adherence Evaluations
Always 148
Usually 9
Sometimes 3
Never taken as prescribed 12
Burden
Burden Evaluations
Very hard to take 11
Somewhat hard to take 9
A little hard to take 16
Not at all hard to take 136
Cost per month
Cost per month Evaluations
$200+ 5
$100-199 3
$50-99 8
$25-49 16
< $25 77
Not specified 63

What people switch to and from

Patients started taking Leflunomide after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 50
Hydroxychloroquine (Plaquenil) 20
Sulfasalazine (Salazopyrin) 7
Azathioprine (Imuran) 5
Adalimumab (Humira) 3

Show all 15 treatments patients report switching from

Patients stopped taking Leflunomide and switched to:

Treatment Patients
Methotrexate (Apo-Methotrexate) 9
Etanercept (Enbrel SureClick) 7
Adalimumab (Humira) 6
Azathioprine (Imuran) 4
Sulfasalazine (Salazopyrin) 4

Show all 16 treatments patients report switching to

Last updated:

5 patient evaluations for Leflunomide

Dec 6, 2016 (Started Jan 30, 2014)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Moderate (upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

May 15, 2014 (Started Jan 30, 2014)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Moderate (upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily

  • 0 helpful marks

Mar 16, 2012 (Started Dec 12, 2011)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Jul 4, 2011 (Started Apr 15, 2011)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 20 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Leflunomide