What is Leflunomide?

Category: Prescription Drugs

Most popular types: Arava

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Leflunomide is a disease modifying antirheumatic drug used to treat active rheumatoid arthritis to reduce symptoms, retard structural damage and improve physical function. Also use as to prevent rejection in organ transplants.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Rheumatoid arthritis 303 111
Systemic lupus erythematosus 32 18
Psoriatic arthritis 15 13
Arthritis pain 4 1
BK virus 4 0

Show all 27 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 35
Moderate 37
Mild 29
None 50

Commonly reported side effects and conditions associated with Leflunomide

Side effect Patients
Diarrhea 16
Nausea 11
Hair loss 9
Elevated liver enzymes 4
Headaches 4
Upset stomach 4

Show all 71 reported side effects

Dosages

Based on patients currently taking Leflunomide

Dosage Patients
20 mg daily 24
10 mg daily 11
45 mg every 12 weeks 1
10 mg twice daily 1
20 mg twice daily 1
100 mg daily 1

Why patients stopped taking Leflunomide

Multiple reasons could be selected

Reason Patients
Side effects too severe 77
Did not seem to work 65
Doctor's advice 58
Other 14
Expense 6
Personal research 4
Course of treatment ended 3
See all 155 patients who've stopped taking Leflunomide

Duration

Currently taking Leflunomide

Duration Patients
Less than 1 month 1
1 - 6 months 10
6 months - 1 year 3
1 - 2 years 5
2 - 5 years 11
5 - 10 years 10
10 years or more 1

Stopped taking Leflunomide

Duration Patients
Less than 1 month 28
1 - 6 months 48
6 months - 1 year 39
1 - 2 years 19
2 - 5 years 16
5 - 10 years 5
10 years or more 1
Adherence
Adherence Evaluations
Always 130
Usually 9
Sometimes 3
Never taken as prescribed 9
Burden
Burden Evaluations
Very hard to take 11
Somewhat hard to take 9
A little hard to take 15
Not at all hard to take 116
Cost per month
Cost per month Evaluations
$200+ 5
$100-199 2
$50-99 7
$25-49 12
< $25 69
Not specified 56

What people switch to and from

Patients started taking Leflunomide after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 36
Hydroxychloroquine (Plaquenil) 18
Sulfasalazine (Salazopyrin) 6
Prednisone (Deltasone) 4
Azathioprine (Imuran) 3

Show all 13 treatments patients report switching from

Patients stopped taking Leflunomide and switched to:

Treatment Patients
Methotrexate (Apo-Methotrexate) 7
Adalimumab (Humira) 6
Etanercept (Enbrel SureClick) 5
Azathioprine (Imuran) 4
Belimumab (Benlysta) 2

Show all 12 treatments patients report switching to

Last updated:

5 patient evaluations for Leflunomide

Dec 6, 2016 (Started Jan 30, 2014)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Moderate (upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

May 15, 2014 (Started Jan 30, 2014)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    Moderate (upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily

  • 0 helpful marks

Mar 16, 2012 (Started Dec 12, 2011)

  • Effectiveness
    None (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Jul 4, 2011 (Started Apr 15, 2011)

  • Effectiveness
    Can’t tell (for rheumatoid arthritis)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 20 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Leflunomide