What is Acetaminophen-aspirin-caffeine?

Category: Over the Counter Drugs

Most popular types: Excedrin Migraine Excedrin Excedrin Extra Strength Show all

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See also: Acetaminophen (Paracetamol) Caffeine

The combination of acetaminophen (paracetomol), aspirin, and caffeine is used in many over-the-counter products for the treatment of migraine headaches.

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 4
Moderate 9
Mild 12
None 46

Commonly reported side effects and conditions associated with Acetaminophen-aspirin-caffeine

Side effect Patients
Stomach pain 7
Stomach upset 6
Jittery feeling 5
Acid reflux 3
Headache aggravated 2
Bladder problems 1

Show all 27 reported side effects

Dosages

Based on patients currently taking Acetaminophen-aspirin-caffeine

Dosage Patients
2 250mg-250mg-65mg as needed 25
250mg-250mg-65mg as needed 17
3 250mg-250mg-65mg as needed 4
250 mg-250 mg-65 mg daily 3
250 mg-250 mg-65 mg twice daily 2
2 x 250 mg-250 mg-65 mg daily 2
2tablet(s) as needed 2
2 tablet(s) daily 1
3 x 250 mg-250 mg-65 mg daily 1
2 x 250 mg-250 mg-65 mg twice daily 1

See all 17 dosages

Why patients stopped taking Acetaminophen-aspirin-caffeine

Multiple reasons could be selected

Reason Patients
Other 14
Doctor's advice 12
Did not seem to work 8
Side effects too severe 5
Course of treatment ended 2
Expense 1
See all 37 patients who’ve stopped taking Acetaminophen-aspirin-caffeine

Duration

Currently taking Acetaminophen-aspirin-caffeine

Duration Patients
3-6 months 1
6 months-1 year 2
1-2 years 4
2 years or more 57

Stopped taking Acetaminophen-aspirin-caffeine

Duration Patients
0-1 month 5
1-3 months 2
3-6 months 2
6 months-1 year 3
1-2 years 6
2 years or more 20

Adherence


Always
Patients
34
48%
Usually
Patients
23
32%
Sometimes
Patients
12
17%
Never taken as prescribed
Patients
2
3%

Burden


Very hard to take
Patients
0
0%
Somewhat hard to take
Patients
6
8%
A little hard to take
Patients
9
13%
Not at all hard to take
Patients
56
79%

Cost per month


Cost per month
$200+
Patients
0
0%
Cost per month
$100-199
Patients
0
0%
Cost per month
$50-99
Patients
0
0%
Cost per month
$25-49
Patients
3
4%
Cost per month
< $25
Patients
36
51%
Cost per month
Not specified
Patients
32
45%
Last updated:

9 patient evaluations for Acetaminophen-aspirin-caffeine

tloree
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tloree
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: none
Swallowing: moderate
Upper limb: mild
Walking: moderate
I am: n
I have:
MS

See tloree's full Acetaminophen-aspirin-caffeine history

Dec 12, 2015 (Started Sep 01, 2004)

  • Effectiveness
    Major (for Migraine headaches)
  • Effectiveness
    Major (for Headaches)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly

  • 0 helpful marks
ashlynn220
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ashlynn220
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: Some
Sleep: Some
Stiffness: Most
function: Most
external_stress: Little
Stickman: most
Description:F29y
FM:7y Dx
I am: b
I have:
Fibromyalgia

See ashlynn220's full Acetaminophen-aspirin-caffeine history

Apr 26, 2011 (Started Apr 15, 2009)

  • Effectiveness
    Moderate (for Neck pain)
  • Effectiveness
    Major (for Migraine headaches)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks
Rikka
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Rikka
Gender: F
Data Quality: 1 star
Depression: 2
Mania: 2
Emotional: 4
Anxiety: 4
Compulsion: 4
External Stress: Overwhelming
32 F
Function: Low
Distress: High
I am: b
I have:
Social Anxiety Disorder

See Rikka's full Acetaminophen-aspirin-caffeine history

Feb 4, 2011 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • side effects
    Mild (Headache aggravated, Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: When I have a migraine, it takes a couple of doses for the Excedrin to really work. The bonus is that it takes away a lot of the tension in my neck and shoulders, if only for a few hours.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

Oct 18, 2010 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • side effects
    Mild (Headache aggravated, Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I take Excedrin at the first sign of a headache, basically to take the edge off of any migraine that may be forming. It never takes the whole thing away, but it helps to reduce the pain enough that I don't tense up and make it worse. The only type of Excedrin that works for me is the regular (original) tablets, extra strength. All of the other varieties, such as the capsules, have much less of a positive impact on my headaches.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

Nov 28, 2009 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • side effects
    Mild (Headache aggravated, Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: Make sure that you take with something else in your stomach, like food or orange juice; especially if you have stomach ulcers. Do not ever take more than three, and give yourself at least 8 hours before bed without Excedrin. If the headache worsens, don't take the next dose.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

Apr 18, 2009 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • side effects
    Mild (Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Don't forget to eat, and limit the consumption of coffee and soda while taking it.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

  • 0 helpful marks
Last updated:
Showing 3 of 9 patient evaluations for Acetaminophen-aspirin-caffeine