What is Acetaminophen-aspirin-caffeine?

Category: Over the Counter Drugs

Most popular types: Excedrin Migraine Excedrin Excedrin Extra Strength Show all

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See also: Acetaminophen (Paracetamol) Caffeine

The combination of acetaminophen (paracetomol), aspirin, and caffeine is used in many over-the-counter products for the treatment of migraine headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Migraine headaches 160 59
Headaches 85 40
Migraine 34 14
Pain 21 2
Neck pain 8 4
Fibromyalgia 6 0

Show all 38 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 3
Moderate 11
Mild 17
None 64

Commonly reported side effects and conditions associated with Acetaminophen-aspirin-caffeine

Side effect Patients
Stomach pain 7
Stomach upset 7
Jittery feeling 5
Acid reflux 3
Headache aggravated 2
Bladder problems 1

Show all 29 reported side effects

Dosages

Based on patients currently taking Acetaminophen-aspirin-caffeine

Dosage Patients
2 250mg-250mg-65mg as needed 16
250mg-250mg-65mg as needed 16
2 x 250 mg-250 mg-65 mg daily 2
2 250-250-65mg as needed 2
250-250-65mg as needed 2
2tablet(s) as needed 2
2 tablet(s) daily 1
250-250-65 mg daily 1
250-250-65 mg three times daily 1
3 x 250 mg-250 mg-65 mg daily 1

See all 16 dosages

Why patients stopped taking Acetaminophen-aspirin-caffeine

Multiple reasons could be selected

Reason Patients
Other 14
Doctor's advice 13
Did not seem to work 9
Side effects too severe 6
Course of treatment ended 2
Expense 1
See all 38 patients who’ve stopped taking Acetaminophen-aspirin-caffeine

Duration

Currently taking Acetaminophen-aspirin-caffeine

Duration Patients
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 2
2 - 5 years 9
5 - 10 years 21
10 years or more 15

Stopped taking Acetaminophen-aspirin-caffeine

Duration Patients
Less than 1 month 4
1 - 6 months 4
6 months - 1 year 4
1 - 2 years 6
2 - 5 years 8
5 - 10 years 5
10 years or more 8
Adherence
Adherence Evaluations
Always 45
Usually 30
Sometimes 16
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 11
A little hard to take 15
Not at all hard to take 69
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 0
$25-49 4
< $25 55
Not specified 36
Last updated:

9 patient evaluations for Acetaminophen-aspirin-caffeine

76 members have decided to share their profiles only with other members of PatientsLikeMe.

tloree
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tloree
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: none
Swallowing: moderate
Upper limb: mild
Walking: moderate
I am: n
I have:
MS

See tloree's full Acetaminophen-aspirin-caffeine history

Dec 12, 2015 (Started Sep 01, 2004)

  • Effectiveness
    Major (for Migraine headaches)
  • Effectiveness
    Major (for Headaches)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly

  • 0 helpful marks
ashlynn220
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ashlynn220
Gender: F
Data Quality: 1 star
Pain: Most
Fatigue: Some
Sleep: Some
Stiffness: Most
function: Most
external_stress: Little
Stickman: most
Description:F29y
FM:7y Dx
I am: b
I have:
Fibromyalgia

See ashlynn220's full Acetaminophen-aspirin-caffeine history

Apr 26, 2011 (Started Apr 15, 2009)

  • Effectiveness
    Moderate (for Neck pain)
  • Effectiveness
    Major (for Migraine headaches)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks
Rikka
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Rikka
Gender: F
Data Quality: 1 star
Depression: 2
Mania: 2
Emotional: 4
Anxiety: 4
Compulsion: 4
External Stress: Overwhelming
32 F
Function: Low
Distress: High
I am: b
I have:
Social Anxiety Disorder

See Rikka's full Acetaminophen-aspirin-caffeine history

Feb 4, 2011 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • Side effects
    Mild (Headache aggravated, Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: When I have a migraine, it takes a couple of doses for the Excedrin to really work. The bonus is that it takes away a lot of the tension in my neck and shoulders, if only for a few hours.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

Oct 18, 2010 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • Side effects
    Mild (Headache aggravated, Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I take Excedrin at the first sign of a headache, basically to take the edge off of any migraine that may be forming. It never takes the whole thing away, but it helps to reduce the pain enough that I don't tense up and make it worse. The only type of Excedrin that works for me is the regular (original) tablets, extra strength. All of the other varieties, such as the capsules, have much less of a positive impact on my headaches.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

Nov 28, 2009 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • Side effects
    Mild (Headache aggravated, Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: Make sure that you take with something else in your stomach, like food or orange juice; especially if you have stomach ulcers. Do not ever take more than three, and give yourself at least 8 hours before bed without Excedrin. If the headache worsens, don't take the next dose.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

Apr 18, 2009 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for Migraine headaches)
  • Side effects
    Mild (Stomach upset, Jittery feeling, Stomach pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Don't forget to eat, and limit the consumption of coffee and soda while taking it.
Cost: < $25 monthly
Side effects: Stomach upset, Jittery feeling, Stomach pain, Headache aggravated

  • 0 helpful marks
Last updated:
Showing 3 of 9 patient evaluations for Acetaminophen-aspirin-caffeine