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What is Acetaminophen-aspirin-caffeine?

Category: Over the Counter Drugs

Most popular types: Excedrin Migraine Excedrin Excedrin Extra Strength Show all

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The combination of acetaminophen (paracetomol), aspirin, and caffeine is used in many over-the-counter products for the treatment of migraine headaches.

See patients taking Acetaminophen-aspirin-caffeine

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Migraine headaches 175 69
Headaches 92 48
Migraine 34 14
Pain 23 2
Neck pain 9 5
Fibromyalgia 6 0

Show all 43 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 370 patients that have taken Acetaminophen-aspirin-caffeine

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 3
Moderate 14
Mild 19
None 77

Commonly reported side effects and conditions associated with Acetaminophen-aspirin-caffeine

Side effect Patients
Stomach pain 8
Upset stomach 8
Jittery feeling 5
Acid reflux 3
Headaches 3
Nausea 2

Show all 31 reported side effects

Dosages

Based on patients currently taking Acetaminophen-aspirin-caffeine

Dosage Patients
2 250-250-65mg as needed 13
2 250mg-250mg-65mg as needed 12
250mg-250mg-65mg as needed 10
2 x 250 mg-250 mg-65 mg daily 6
250-250-65mg as needed 5
2 x 250-250-65 mg daily 4
3 250mg-250mg-65mg as needed 2
2 mg daily 1
2 tablet(s) daily 1
250-250-65 mg daily 1

See all 22 dosages

Why patients stopped taking Acetaminophen-aspirin-caffeine

Multiple reasons could be selected

Reason Patients
Other 15
Doctor's advice 14
Did not seem to work 10
Side effects too severe 6
Course of treatment ended 2
Expense 1
See all 41 patients who've stopped taking Acetaminophen-aspirin-caffeine

Duration

Currently taking Acetaminophen-aspirin-caffeine

Duration Patients
1 - 6 months 2
6 months - 1 year 4
1 - 2 years 1
2 - 5 years 10
5 - 10 years 25
10 years or more 24

Stopped taking Acetaminophen-aspirin-caffeine

Duration Patients
Less than 1 month 4
1 - 6 months 4
6 months - 1 year 4
1 - 2 years 6
2 - 5 years 10
5 - 10 years 6
10 years or more 8
Adherence
Adherence Evaluations
Always 55
Usually 38
Sometimes 16
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 11
A little hard to take 15
Not at all hard to take 87
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 0
$25-49 4
< $25 66
Not specified 42

What people switch to and from

Patients stopped taking Acetaminophen-aspirin-caffeine and switched to:

Treatment Patients
Acetaminophen-isometheptene-dichloralphenazone (Midrin) 1
Botulinum Toxin Type A (Botox) 1
Butalbital-acetaminophen-caffeine (Fioricet) 1
Last updated:

9 patient evaluations for Acetaminophen-aspirin-caffeine

Sort by: Most recent

Dec 12, 2015 (Started Sep 01, 2004)

  • Effectiveness
    Major (for migraine headaches)
  • Effectiveness
    Major (for headaches)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly
  • 0 helpful marks

Apr 26, 2011 (Started Apr 15, 2009)

  • Effectiveness
    Moderate (for neck pain)
  • Effectiveness
    Major (for migraine headaches)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
  • 0 helpful marks

Feb 4, 2011 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for migraine headaches)
  • Side effects
    Mild (headaches, upset stomach, jittery feeling, stomach pain)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: When I have a migraine, it takes a couple of doses for the Excedrin to really work. The bonus is that it takes away a lot of the tension in my neck and shoulders, if only for a few hours.
Cost: < $25 monthly
Side effects: headaches, upset stomach, jittery feeling, stomach pain

Oct 18, 2010 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for migraine headaches)
  • Side effects
    Mild (headaches, upset stomach, jittery feeling, stomach pain)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I take Excedrin at the first sign of a headache, basically to take the edge off of any migraine that may be forming. It never takes the whole thing away, but it helps to reduce the pain enough that I don't tense up and make it worse. The only type of Excedrin that works for me is the regular (original) tablets, extra strength. All of the other varieties, such as the capsules, have much less of a positive impact on my headaches.
Cost: < $25 monthly
Side effects: headaches, upset stomach, jittery feeling, stomach pain

Nov 28, 2009 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for migraine headaches)
  • Side effects
    Mild (headaches, upset stomach, jittery feeling, stomach pain)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: Make sure that you take with something else in your stomach, like food or orange juice; especially if you have stomach ulcers. Do not ever take more than three, and give yourself at least 8 hours before bed without Excedrin. If the headache worsens, don't take the next dose.
Cost: < $25 monthly
Side effects: headaches, upset stomach, jittery feeling, stomach pain

Apr 18, 2009 (Started Mar 01, 1994)

  • Effectiveness
    Moderate (for migraine headaches)
  • Side effects
    Mild (upset stomach, jittery feeling, stomach pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Don't forget to eat, and limit the consumption of coffee and soda while taking it.
Cost: < $25 monthly
Side effects: headaches, upset stomach, jittery feeling, stomach pain
  • 0 helpful marks
Last updated:
Showing 3 of 9 patient evaluations for Acetaminophen-aspirin-caffeine